生物螺旋间手性相互作用的扭曲
A twist in chiral interaction between biological helices
摘要:
利用对相互作用势的精确解,我们证明了具有螺旋表面电荷模式的长的刚性手性分子具有优先轴间角~((RH)^1/2)/L,其中L是分子的长度,R是它们的轴之间的最近距离,H是螺距。基于这个公式的估计提出了一个解决方案的困惑小轴间角在a-螺旋束和DNA的双相。
英文摘要:
Using an exact solution for the pair interaction potential, we show that long, rigid, chiral molecules with helical surface charge patterns have a preferential interaxial angle ~((RH)^1/2)/L, where L is the length of the molecules, R is the closest distance between their axes, and H is the helical pitch. Estimates based on this formula suggest a solution for the puzzle of small interaxial angles in a-helix bundles and in cholesteric phases of DNA.
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