The Genetic Code as a Chronicle of Early Events in the Origin of Life

生命起源的稳定性蒸馏假说

Stability distillation hypothesis for the origin of life

本文提出稳定性蒸馏假说，通过统一机制（稳定性差异驱动的选择性富集）从随机化学逐步推导出遗传系统，论证生命起源是特定边界条件下的必然涌现而非偶然奇迹。

遗传密码演化中保真度与多样性的相互作用

Interplay of Fidelity and Diversity in the Evolution of the Genetic Code

研究标准遗传密码是否为平衡错误负载与氨基酸组成的近优解，通过模拟退火发现其位于局部最优解附近，揭示了保真度与多样性冲突压力下的协同演化机制。

Towards Understanding the Origin of Genetic Languages

Molecular biology is a nanotechnology that works--it has worked for billions of years and in an amazing variety of circumstances. At its core is a system for acquiring, processing and communicating information that is universal, from viruses and bacteria to human beings. Advances in genetics and experience in designing computers have taken us to a stage where we can understand the optimisation principles at the root of this system, from the availability of basic building blocks to the execution of tasks. The languages of DNA and proteins are argued to be the optimal solutions to the informatio…

Matrix genetics, part 3: the evolution of the genetic code from the viewpoint of the genetic octave Yin-Yang-algebra

The set of known dialects of the genetic code (GC) is analyzed from the viewpoint of the genetic octave Yin-Yang-algebra. This algebra was described in the previous author's publications. The algebra was discovered on the basis of structural features of the GC in the matrix form of its presentation ("matrix genetics"). The octave Yin-Yang-algebra is considered as the pre-code or as the model of the GC. From the viewpoint of this algebraic model, for example, the sets of 20 amino acids and of 64 triplets consist of sub-sets of "male", "female" and "androgynous" molecules, etc. This algebra perm…