Framework and Bio-Mechanical Model for a Per-Operative Image-Guided Neuronavigator Including 'Brain-Shift' Compensation

Bio-Mechanical Model of the Brain for a Per-Operative Image-Guided Neuronavigator Compensating for "Brain-Shift" Deformations

In this paper we present a methodology to address the problem of brain tissue deformation referred to as 'brain-shift'. This deformation occurs throughout a neurosurgery intervention and strongly alters the accuracy of the neuronavigation systems used to date in clinical routine which rely solely on pre-operative patient imaging to locate the surgical target, such as a tumour or a functional area. After a general description of the framework of our intra-operative image-guided system, we describe a procedure to generate patient specific finite element meshes of the brain and propose a biomecha…

Framework for a low-cost intra-operative image-guided neuronavigator including brain shift compensation

In this paper we present a methodology to address the problem of brain tissue deformation referred to as 'brain-shift'. This deformation occurs throughout a neurosurgery intervention and strongly alters the accuracy of the neuronavigation systems used to date in clinical routine which rely solely on pre-operative patient imaging to locate the surgical target, such as a tumour or a functional area. After a general description of the framework of our intra-operative image-guided system, we describe a procedure to generate patient specific finite element meshes of the brain and propose a biomecha…

腹股沟疝生物力学综述

A review of ventral hernia biomechanics

本文综述探讨了腹疝的生物力学机制，强调生物力学在手术决策中的重要性，提出通过优化手术技术和材料选择以降低复发率。

Computer aided planning for orthognatic surgery

A computer aided maxillofacial sequence is presented, applied to orthognatic surgery. It consists of 5 main stages: data acquisition and integration, surgical planning, surgical simulation, and per operative assistance. The planning and simulation steps are then addressed in a way that is clinically relevant. First concepts toward a 3D cephalometry are presented for a morphological analysis, surgical planning, and bone and soft tissue simulation. The aesthetic surgical outcomes of bone repositioning are studied with a biomechanical Finite Element soft tissue model.

Real-time Prediction of Soft Tissue Deformations Using Data-driven Nonlinear Presurgical Simulations

Imaging modalities provide clinicians with real-time visualization of anatomical regions of interest (ROI) for the purpose of minimally invasive surgery. During the procedure, low-resolution image data are acquired and registered with high-resolution preoperative 3D reconstruction to guide the execution of surgical preplan. Unfortunately, due to the potential large strain and nonlinearities in the deformation of soft biological tissues, significant mismatch may be observed between ROI shapes during pre- and intra-operative imaging stages, making the surgical preplan prone to failure. In an eff…

Large Field, High Resolution Full Field Optical Coherence Tomography: A Pre-clinical study of human breast tissue and cancer assessment

We present a benchmark pilot study in which high-resolution Full-Field Optical Coherence Tomography (FF-OCT) is used to image human breast tissue and is evaluated to assess its ability to aid the pathologist's management of intra-operative diagnoses. Our aim included evaluating the safety of FF-OCT on human tissue and determining the concordance between the images obtained with routinely prepared histopathological material. The compact device used for this study provides a 2 μm-lateral and a 1 μm-axial resolution, and is able to scan a 1.5cm^2 specimen in about 7 minutes. 75 breast specimens o…