生物力学在计算机辅助诊断中的应用：以眼眶和颌面外科手术为例
Biomechanics applied to computer-aided diagnosis: examples of orbital and maxillofacial surgeries
摘要：
本文介绍了我们小组提出的方法来模拟生物软组织变形，并将这些模型与计算机辅助手术（CAS）的应用程序。在设计了主要关注骨结构的CAS协议后，实验室TIMC（CNRS，法国）的计算机辅助医学成像组现在试图考虑CAS背景下软组织的行为。为此，已经提出了一种方法，最初以网格匹配方法的名称发表，以详细说明患者特定的模型。从给定解剖结构的精心手动构建的“通用”有限元（FE）模型开始，通过非线性弹性配准算法自动生成适合每个新患者的几何形状的模型（“患者特定”FE模型）。本文介绍了网格匹配方法的一般方法，并说明了这一过程中的两个临床应用，即眼眶和颌面部计算机辅助手术。
英文摘要：
This paper introduces the methodology proposed by our group to model the biological soft tissues deformations and to couple these models with Computer-Assisted Surgical (CAS) applications. After designing CAS protocols that mainly focused on bony structures, the Computer Aided Medical Imaging group of Laboratory TIMC (CNRS, France) now tries to take into account the behaviour of soft tissues in the CAS context. For this, a methodology, originally published under the name of the Mesh-Matching method, has been proposed to elaborate patient specific models. Starting from an elaborate manually-built "generic" Finite Element (FE) model of a given anatomical structure, models adapted to the geometries of each new patient ("patient specific" FE models) are automatically generated through a non-linear elastic registration algorithm. This paper presents the general methodology of the Mesh-Matching method and illustrates this process with two clinical applications, namely the orbital and the maxillofacial computer-assisted surgeries.
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