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arXiv physics/0505191physics.bio-phq-bio.CBq-bio.SC
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肌动蛋白基推进中的细丝附着动力学;

Filament attachment dynamics in actin-based propulsion

J. I. Katz, A. E. Carlsson

摘要:

理论和实验已经证实,F-肌动蛋白丝强烈地附着在细胞内寄生虫(如李斯特菌)上,它们用“彗星尾巴”推进。我们认为这些意见的推进的影响。通过计算各种附着体模型的运动,并与实验结果进行比较,我们证明了附着体必须是滑动的而不是铰接的。通过对ActA涂层球体的建模实验,我们得出了关于F-肌动蛋白和它们的表面之间的相互作用的结论,这些结论也可能适用于生命系统。

英文摘要:

Theory and experiment have established that F-actin filaments are strongly attached to the intracellular parasites (such as Listeria) they propel with ``comet tails''. We consider the implications of these observations for propulsion. By calculating the motion produced in various models of attachment and comparing to experiment we demonstrate that the attachment must be sliding rather than hinged. By modeling experiments on ActA-coated spheres we draw conclusions regarding the interaction between F-actin and their surfaces that may also be applicable to living systems.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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