arXivDaily arXiv每日学术速递 周一至周五更新
arXiv physics/0410147physics.bio-phphysics.med-phq-bio.QM
收藏

不同能量轻离子灭活细胞机理的模拟

Modelling the mechanism of cell inactivation by light ions at different energy values

Pavel Kundrat, Hana Hromcikova, Milos Lokajicek

摘要:

质子和轻离子在放射治疗中的有效应用,相应的放射生物学机制的详细知识和现实的模型是必要的。该机制的基本特征已表示在概率两阶段模型。区分了单个粒子穿越后立即发生的过程和细胞对所有粒子形成的总损伤的反应。该模型还涉及DNA损伤形成和修复过程的概率描述。

英文摘要:

For efficient application of protons and light ions in radiotherapy, detailed knowledge and realistic models of the corresponding radiobiological mechanism are necessary. Basic characteristics of this mechanism have been represented within a probabilistic two-stage model. The processes that occur immediately after the traversals of individual particles and the response of cell to the total damage formed by all the particles have been distinguished. The model involves a probabilistic description of DNA damage formation and repair processes, too.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑