凝胶在溶胀梯度中的运动:细胞运动的一种机制
Motion of an Adhesive Gel in a Swelling Gradient: a Mechanism for Cell Locomotion
摘要:
出于运动的线虫精子细胞,我们提出了一个模型的固体基板上的粘合剂凝胶的运动。凝胶在前缘聚合,在后部解聚。这种运动是由于自生的溶胀梯度与基底上的粘附力之间的竞争而产生的。由此产生的应力引起粘合点的破裂并允许运动。该模型预测了一种不寻常的力-速度关系,这种关系在很大程度上取决于力的施加点。
英文摘要:
Motivated by the motion of nematode sperm cells, we present a model for the motion of an adhesive gel on a solid substrate. The gel polymerizes at the leading edge and depolymerizes at the rear. The motion results from a competition between a self-generated swelling gradient and the adhesion on the substrate. The resulting stress provokes the rupture of the adhesion points and allows for the motion. The model predicts an unusual force-velocity relation which depends in significant ways on the point of application of the force.
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