成纤维细胞高度波动的原子力显微镜研究
Atomic Force Microscopy of height fluctuations of fibroblast cells
摘要：
利用原子力显微镜（AFM）研究了生理条件下3 T3成纤维细胞在纳米尺度上的高度波动。可以观察到这些波动和侧向细胞运动之间的相关性。在前缘测量的波动似乎主要与肌动蛋白聚合-解聚过程有关。我们发现在具有低运动性的细胞上具有1- 2nm幅度的快速（5 Hz）的反射行为，显示强调的应力纤维结构。肌球蛋白驱动的应力纤维的收缩被认为是引起这种脉动。
英文摘要：
We investigated the nanometer scale height fluctuations of 3T3 fibroblast cells with the atomic force microscope (AFM) under physiological conditions. Correlation between these fluctuations and lateral cellular motility can be observed. Fluctuations measured on leading edges appear to be predominantly related to actin polymerization-depolymerization processes. We found fast (5 Hz) pulsatory behavior with 1--2 nm amplitude on a cell with low motility showing emphasized structure of stress fibres. Myosin driven contractions of stress fibres are thought to induce this pulsation.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
