Condensed Matter的层次理论:水在蛋白质动力学、功能和癌症应急中的作用
Hierarchic Theory of Condensed Matter: Role of water in protein dynamics, function and cancer emergency
摘要:
1.结构域间水分子团簇在蛋白质大尺度动力学中的作用; 2.基于广义Stokes-Einstein和Eyring-Polany方程的蛋白质大尺度动力学描述; 3.蛋白质配体复合物形成的动力学模型; 4.准粒子的寿命及其激发频率; 5.酶催化的介观机理; 6. ATP水解能在肌肉收缩和蛋白质聚合中的利用机制; 7.水活性作为细胞内和细胞间过程的调节因子; 8.水与癌症
英文摘要:
1. Role of inter-domain water clusters in large-scale dynamics of proteins; 2. Description of large-scale dynamics of proteins based on generalized Stokes-Einstein and Eyring-Polany equation; 3. Dynamic model of protein-ligand complexes formation; 4. The life-time of quasiparticles and frequencies of their excitation; 5. Mesoscopic mechanism of enzyme catalysis; 6. The mechanism of ATP hydrolysis energy utilization in muscle contraction and protein polymerization; 7. Water activity as a regulative factor in the intra- and inter-cell processes; 8. Water and cancer.
机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。