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arXiv math/0608417math.STmath.COstat.TH
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联合贝叶斯网络

Conjunctive Bayesian networks

Niko Beerenwinkel, Nicholas Eriksson, Bernd Sturmfels

摘要:

联合贝叶斯网络(CBN)是一种描述事件累积的图形模型,这些事件的发生顺序受到限制。一个CBN由一个(有限)事件集上的偏序给出。CBN通过允许事件的发生取决于一个以上的前驱事件来概括Desper等人的致癌树模型。本文研究了立方氮化硼的统计和代数性质。我们确定的最大似然参数,并提出了一个组合的解决方案的模型选择问题。我们的方法在两个数据集上表现良好,其中事件是与耐药性相关的HIV突变。最后研究了立方氮化硼的代数性质,证明了立方氮化硼经过坐标变换后是复曲面簇,其理想具有二次Gröbner基。

英文摘要:

Conjunctive Bayesian networks (CBNs) are graphical models that describe the accumulation of events which are constrained in the order of their occurrence. A CBN is given by a partial order on a (finite) set of events. CBNs generalize the oncogenetic tree models of Desper et al. by allowing the occurrence of an event to depend on more than one predecessor event. The present paper studies the statistical and algebraic properties of CBNs. We determine the maximum likelihood parameters and present a combinatorial solution to the model selection problem. Our method performs well on two datasets where the events are HIV mutations associated with drug resistance. Concluding with a study of the algebraic properties of CBNs, we show that CBNs are toric varieties after a coordinate transformation and that their ideals possess a quadratic Gröbner basis.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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