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arXiv math/0506082math.COcs.DMmath.MGq-bio.GN
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蛋白质离散differential geometry:一种编码蛋白质三维结构的新方法

Discrete differential geometry of proteins: a new method for encoding three-dimensional structures of proteins

Naoto Morikawa

摘要:

在自然界中,蛋白质的三维结构由相应的基因编码。在本文中,我们描述了一种新的方法编码的三维结构的蛋白质到一个二进制序列。该方法的特点是蛋白质折叠和“整合”之间的对应关系。蛋白质近似于折叠的四面体序列。蛋白质的二进制代码是作为折叠四面体序列形状的“二阶导数”获得的。利用这种方法,我们可以从基因中提取蛋白质的静态结构信息。我们可以描述蛋白质的三维结构的分布,而无需任何主观的层次分类。

英文摘要:

In nature the three-dimensional structure of a protein is encoded in the corresponding gene. In this paper we describe a new method for encoding the three-dimensional structure of a protein into a binary sequence. The feature of the method is the correspondence between protein-folding and ``integration''. A protein is approximated by a folded tetrahedron sequence. And the binary code of a protein is obtained as the ``second derivative'' of the shape of the folded tetrahedron sequence. With this method at hand, we can extract static structural information of a protein from its gene. And we can describe the distribution of three-dimensional structures of proteins without any subjective hierarchical classification.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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