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解耦、净化与统一:面向联邦医学分割的语义-结构原型学习

Decouple, Purify and Unite: Semantic-Structural Prototype Learning for Federated Medical Segmentation

Xingyue Zhao, Wenke Huang, Linghao Zhuang, Yanzhou Su, Zhifeng Wang, Haoyu Zhao, Mengfan Li, Junjun He, Tao Tan, Dakai Jin, Le Lu, Mang Ye, Qiang Yang, Ming Feng

arXiv 2610.04700首次发表:更新:

发表机构

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Beijing University of Posts and Telecommunications; Nanyang Technological University; Ant Group; Shanghai Innovation Institute; Institute of Automation, Chinese Academy of Sciences; DAMO Academy, Alibaba Group; Fourth Military Medical University; Macao Polytechnic University; Wuhan University; The Hong Kong Polytechnic University(北京协和医院,中国医学科学院北京协和医学院; 北京邮电大学; 南洋理工大学; 蚂蚁集团; 上海创新研究院; 中国科学院自动化研究所; 阿里巴巴达摩院; 中国人民解放军空军军医大学; 澳门理工大学; 武汉大学; 香港理工大学)

机构由 AI 辅助整理,请以论文原文为准。

AI 中文总结

针对联邦医学分割中的特征异质性,提出FedBCS+,通过频域风格重校准解耦内容与风格,并分别对齐语义与结构原型,自适应聚合减少偏差,在五个基准上取得最优平均Dice。

AI 中文摘要

联邦学习使医疗机构能够在无需共享数据的情况下训练全局模型,然而来自不同扫描仪或协议的特征异质性仍然具有挑战性。现有的基于表示的方法面临两个局限:1)不完整的上下文表示学习:单层或耦合的表示忽视了多层级的结构线索,并将区域语义与边界细节纠缠在一起。2)逐层风格与聚合偏差:中间层跨域的特定风格差异会降低原型质量,而忽略客户端分布偏移的聚合可能进一步放大偏差。我们提出FedBCS+,一种联邦解耦上下文对齐与风格净化聚合方法。我们在原型构建中采用频域风格重校准(FSR)来解耦内容-风格表示并提取风格净化的原型。基于这些净化特征,解耦上下文原型对齐(DCPA)明确地将多层级特征解耦为语义原型和结构原型,并分别对齐区域语义和细粒度解剖结构。风格净化语义原型聚合(S2PA)衡量每个客户端的净化原型与全局共识的差异,并自适应地重新加权聚合,偏向代表性不足的客户端以减少共识偏差。在涵盖组织病理学、MRI、超声和结肠镜检查的五个异构医学分割基准上,FedBCS+在比较方法中取得了最高的平均Dice。收敛性分析进一步刻画了聚合和对齐如何影响优化界。

英文摘要

Federated learning enables medical institutions to train a global model without sharing data, yet feature heterogeneity from diverse scanners or protocols remains challenging. Existing representation-based methods face two limitations: 1) Incomplete Contextual Representation Learning: single-layer or coupled representations overlook multi-level structural cues and entangle regional semantics with boundary details. 2) Layerwise Style and Aggregation Biases: domain-specific style discrepancies across intermediate layers degrade prototypes, while aggregation that overlooks client distribution shifts can further amplify bias. We propose FedBCS+, federated decoupled contextual alignment with style-purified aggregation. We employ Frequency-domain Style Recalibration (FSR) in prototype construction to decouple content-style representations and extract style-purified prototypes. Built upon these purified features, Decoupled Contextual Prototype Alignment (DCPA) explicitly decouples multi-level features into semantic and structural prototypes and aligns regional semantics and fine-grained anatomical structures separately. Style-purified Semantic Prototype Aggregation (S2PA) measures each client's purified prototype divergence from the global consensus and adaptively reweights aggregation toward under-represented clients to reduce consensus bias. On five heterogeneous medical segmentation benchmarks spanning histopathology, MRI, ultrasound, and colonoscopy, FedBCS+ achieves the highest mean Dice among the compared methods. A convergence analysis further characterizes how aggregation and alignment affect the optimization bound.

Comments17 pages, 9 figures, 7 tables

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