优化磁性纳米颗粒组装体中偶极相互作用的磁性热疗效率的结构依赖性
Optimizing the magnetic hyperthermia efficiency from the structural dependence of dipolar interactions in magnetic nanoparticles assemblies
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中文总结 AI 辅助
本研究利用时间量化蒙特卡洛框架，揭示磁性纳米颗粒各向异性聚集体中局部结构（位置与易轴分布）对偶极相互作用贡献的关键作用，为优化磁性热疗效率提供自洽建模方法。
中文摘要 AI 辅助
磁性热疗基于磁性纳米颗粒（MNP）在交变外场下将磁能转化为热能，具有重大意义，尤其在癌症治疗等有前景的进展方面。MNP组装体在激发场下的频率依赖性响应一方面取决于MNP的个体特性，如尺寸、形状和磁晶各向异性，另一方面取决于MNP之间相互作用产生的集体特性。由于后者具有长程偶极分量，其首要后果是所谓的退磁效应，使响应依赖于外部样品形状。因此，研究各向异性外部形状（如薄膜、链或细长聚集体）的MNP组装体的性质具有重要意义。在本工作中，利用最近开发的用于动态模拟的时间量化蒙特卡洛（TQMC）框架，我们更精确地关注此类各向异性聚集体中局部结构对偶极相互作用对外场响应贡献的重要性。这里局部结构既指纳米颗粒的位置，也指其易轴的分布。我们表明，后者必须以自洽方式确定，从铁磁流体建模为偶极硬球流体的平衡结构出发。
英文摘要
Magnetic hyperthermia, based on the conversion of the magnetic energy of magnetic nanoparticles (MNP) under an alternating external field into heat, presents a great interest, especially because of important applications such as promising advances in cancer treatment. The underlying frequency-dependent response of the MNP assembly under the excitation field depends on the first hand on the individual properties of the MNP such as their size, shape and magnetocrystalline anisotropy and on the other hand on collective properties generated by interactions between MNP. Due to the long-range dipolar component of the latter, the first consequence is the so-called demagnetizing effects, making the response dependent on the external sample shape. This is the reason for studying the properties of MNP in assemblies of anisotropic external shapes such as films, chains, or elongated aggregates. In the present work, using a recently developed Time Quantified Monte Carlo (TQMC) framework for dynamic simulations, we focus more precisely on the importance of the local structure in such anisotropic aggregates to the dipolar interactions contribution of the response to the external field. Here the local structure is understood as both the location of the nanoparticles and the distribution of their easy axes. We show that the latter must be determined in a self-consistent way starting with the equilibrium structure of a ferrofluid modeled as the dipolar hard sphere fluid.
发表机构
- PROMES-CNRS (UPR-8521), Université de Perpignan Via Domitia（普罗梅斯-CNRS（UPR-8521），佩皮尼昂维亚多米蒂亚大学）
- ICMPE, UMR 7182 CNRS and UPE（ICMPE，CNRS UMR 7182 和 UPE）
机构由 AI 辅助整理，请以论文原文为准。
