生理信息驱动的数字听诊用于长期护理居民肺炎检测
Physiologically Informed Digital Auscultation for Pneumonia Detection in Long-term Care Residents
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- University of Washington(华盛顿大学)
- University of Washington Bothell(华盛顿大学博塞尔分校)
- Virufy (The Covid Detection Foundation)(Virufy(新冠检测基金会))
- University of Tsukuba(筑波大学)
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中文总结 AI 辅助
本研究利用多通道数字听诊和深度学习,以X光监督训练CNN模型,在长期护理居民中实现高效肺炎检测,优于临床监督并减少通道数。
中文摘要 AI 辅助
肺炎在老年长期护理居民中难以诊断;多病共存和非典型表现掩盖了体征,这促使需要操作高效的客观检测方法。我们分析了来自185名日本居民(73名肺炎患者,112名有症状但非肺炎患者)的多通道数字听诊器录音,使用放射科医生确认的胸部X光片和临床医生诊断作为监督信号,训练卷积神经网络、多模态融合及基于通道的变体,并采用时域Grad-CAM可解释性。模型通过重复的患者级交叉验证进行评估,结果显示,使用X光监督的模型优于临床监督(F1 0.729,准确率0.783,对比F1 0.637,准确率0.711)。此外,三通道选择协议保持了性能(F1 0.736;准确率0.803),其中两个中胸部位排名最高,且Grad-CAM注意力与附加呼吸音重叠。这些发现表明,自动化多通道肺音分析可辅助长期护理中的肺炎诊断,其中X光监督比临床监督更可靠,且较少的通道在降低采集时间的同时保持了性能。
英文摘要
Pneumonia is difficult to diagnose in older long-term care residents; multimorbidity and atypical presentations obscure signs, motivating operationally efficient objective testing. We analyzed multi-channel digital stethoscope recordings from 185 Japanese residents (73 pneumonia, 112 symptomatic without), using radiologist-confirmed chest X-rays and clinician diagnoses as supervisory signals that train convolutional neural networks, multimodal fusion, and channel-based variants with time-domain Grad-CAM interpretability. Models were evaluated with repeated patient-level cross-validation showing models with X-ray supervision outperformed clinician supervision (F1 0.729, accuracy 0.783 vs. F1 0.637, accuracy 0.711). Additionally, a three-channel selection protocol maintained performance (F1 0.736; accuracy 0.803), with two mid-thoracic sites ranking highest and Grad-CAM attention overlapping adventitious sounds. These findings indicate automated multi-channel lung-sound analysis can aid long-term care pneumonia diagnosis, with X-ray supervision being more reliable than clinical, and fewer channels preserving performance while lowering acquisition times.