生物系统中的相干性
Coherence in Biological Systems
- Oranim College of Education（奥拉尼姆教育学院）
机构由 AI 辅助整理，请以论文原文为准。
AI总结：
本文提出相干性作为自主细胞向多细胞个体转变的物理描述，通过质心和相互作用构造集体态，并在盘基网柄菌中验证，提供能量约束下的直接检验。
AI中文摘要：
一组自主细胞何时会成为一个多细胞个体？我们提出，相干性为这一转变提供了物理描述。相干性被视为一种全局属性，当可区分的组分允许具有物理意义的集体态空间描述时，该属性便会出现。利用质心和基于相互作用的构造，我们表明，在引入动力学之前，经典物体就可以定义这样的集体态，而简正模式则作为特定的动力学实现出现。我们将这一框架应用于多细胞组织，其中细胞保留其身份，但其独立的个体性被参与有组织的整体所取代。在盘基网柄菌中，cAMP介导的耦合产生群体水平的集体模式，而饥饿则提供了实验上可控的能量约束，影响向多细胞性的转变。该框架通过相互作用衍生的集体本征态以及维持自主组织与集体组织的能量成本，提供了直接的检验方法。因此，相干性可能为多细胞个体性提供一种通用的物理描述，而无需微观量子相干性或内禀波动特性。
英文摘要：
When does a collection of autonomous cells become a multicellular individual? We propose that coherence provides a physical description of this transition. Coherence is treated as a global property arising when distinguishable constituents admit a physically meaningful collective state-space description. Using the center of mass and an interaction-based construction, we show that such collective states can be defined for classical bodies before dynamics is introduced, with normal modes emerging as a particular dynamical realization. We apply this framework to multicellular organization, where cells retain their identities while their independent individuality is replaced by participation in the organized whole. In \emph{Dictyostelium discoideum}, cAMP-mediated coupling produces population-level collective modes, while starvation provides an experimentally controlled energetic constraint on the transition to multicellularity. The framework yields direct tests through interaction-derived collective eigenstates and the energetic cost of maintaining autonomous versus collective organization. Coherence may thus provide a general physical description of multicellular individuality without requiring microscopic quantum coherence or intrinsic wave character.
