在参数不完整时对未控制混杂进行外部校正的风险差偏倚界定
Bounding the Risk Difference Bias Given Incomplete Parameters for Externally Adjusting Uncontrolled Confounding
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中文总结 AI 辅助
本文针对未控制混杂的外部校正,在三个偏倚参数缺失一个时,提出风险差偏倚的尖锐双参数界限,并给出数值示例。
中文摘要 AI 辅助
未控制混杂导致的偏倚可通过多种外部校正公式进行分析。与其他偏倚表达式类似,涉及未控制多分类混杂因素的风险差偏倚公式仅需三个外部可获取的参数:暴露组与非暴露组中混杂因素的患病率,以及混杂因素与结局之间的风险差。本文在三个所需偏倚参数中仅有一个不可用时,提出了风险差偏倚表达式的双参数界限。每个界限在未知参数的完整范围内都是尖锐的。文中提供了一些带图形的数值示例。
英文摘要
Bias due to uncontrolled confounding can be analyzed using several external adjustment formulas. Like other bias expressions, the risk difference bias formula involving an uncontrolled polytomous confounder requires only three externally obtainable parameters: confounder prevalences among the exposed and unexposed and the confounder-outcome risk difference. This paper presents two-parameter bounds on the risk difference bias expression when only one of the three required bias parameters is unavailable. Each bound is sharp over the full range of the unknown parameter. Some numerical examples with graphs are provided.
发表机构
- University of California, Los Angeles (UCLA)(加州大学洛杉矶分校)
- Aarhus University(奥胡斯大学)
机构由 AI 辅助整理,请以论文原文为准。