发表机构
Universidade do Algarve; King’s College London（阿尔加维大学; 伦敦国王学院）
机构由 AI 辅助整理，请以论文原文为准。AI 中文总结
本研究证明常用T1标测序列MOLLI对T2敏感，通过信号建模可直接从MOLLI图像估计T2，实现单次采集同时获得T1和T2图谱，减少扫描时间并提升临床效率。
AI 中文摘要
心脏T1和T2定量磁共振成像（MRI）是一种能够表征多种心肌病理特征的技术。然而，每个参数都需要各自专门的采集序列，这可能耗时较长。在本工作中，我们证明MOLLI——一种常用于T1标测的采集序列——对T2同样敏感，也可用于心肌T2标测。尽管MOLLI并非为T2标测而设计，但其信号演化本质上依赖于T1和T2弛豫。在此，我们证明这种依赖性足够强，使得可以通过适当的信号建模，直接从MOLLI T1加权图像中估计T2。这一发现为从单次MOLLI采集同时获得T1和T2图谱提供了可能性，从而减少总扫描时间，并可能改善患者舒适度和临床吞吐量。
英文摘要
Cardiac T1 and T2 quantitative magnetic resonance imaging (MRI) is a technique that provides characterization of a multitude of myocardial pathologies. However, each parameter requires its own specialized acquisition sequence, which may be time-consuming. In this work, we demonstrate that MOLLI, an acquisition sequence commonly used to perform T1 mapping, is also sensitive to T2, and can also be used for myocardial T2 mapping. Although MOLLI is not designed for T2 mapping, its signal evolution inherently depends on both T1 and T2 relaxation. Here, we demonstrate that this dependence is sufficiently strong to allow T2 estimation directly from MOLLI T1-weighted images, using appropriate signal modelling. This finding opens the possibility of obtaining simultaneously T1 and T2 maps from a single MOLLI acquisition, reducing total scan time and potentially improving patient comfort and clinical throughput.
