3D计算建模：主动脉附近肿瘤微波消融中的血管热沉效应
3D Computational Modeling of the Vascular Heat-Sink Effect in Microwave Ablation of Tumors Close to the Aorta
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- Yonsei University (Mirae Campus)（延世大学(原州校区)）
- School of Mathematics and Computing, Yonsei University（延世大学数学与计算学院）
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中文总结 AI 辅助
本研究构建ANSYS数值框架，通过等效热源模拟和参数研究，量化了主动脉附近肿瘤微波消融中血流导致的热沉效应，强调仿真辅助治疗计划的重要性。
中文摘要 AI 辅助
微波消融（MWA）是一种经皮消融技术，通过在肿瘤组织内产生局部高温区域来诱导热坏死。然而，当肿瘤位于靠近主动脉等大血管的位置时，血流会持续带走消融区域的热量。这一现象导致血管热沉效应，从而增加消融不完全的风险。本研究构建了一个基于ANSYS的数值框架，以研究靠近主动脉的肿瘤在微波消融过程中的热沉效应。计算模型包括肿瘤、周围组织、血管壁、血流区域和微波天线。微波诱导的加热通过从高频结构仿真器（HFSS）导出的体积损耗密度映射得到的等效热源来表示，而非在热-流体求解器中进行直接电磁-热耦合。进行了两项参数研究以量化热沉效应。首先，在D = 0 mm、4 mm和8.5 mm处改变肿瘤-主动脉距离，以评估血管邻近程度对温度升高和消融区域形成的影响。其次，在每个肿瘤-主动脉距离下，比较了三种血流条件：无血流、停滞血流V = 0 m/s和正常主动脉血流V = 0.65 m/s。这一比较使得血流的热沉效应得以独立评估。结果凸显了对于肿瘤靠近大血管的患者，基于仿真的治疗计划具有临床必要性。
英文摘要
Microwave ablation (MWA) is a percutaneous ablation that induces thermal necrosis by generating localized high-temperature regions within tumor tissue. However, when a tumor is located close to a large vessel such as the aorta, blood flow continuously removes heat from the ablation zone. This phenomenon causes the vascular heat-sink effect and thereby increases the risk of incomplete ablation. This study constructs an ANSYS-based numerical framework to investigate the heat-sink effect during MWA of tumors located close to the aorta. The computational model consists of the tumor, surrounding tissue, vessel wall, blood flow domain, and microwave antenna. Microwave-induced heating was represented by an equivalent heat source mapped from the High-Frequency Structure Simulator (HFSS)-derived volume loss density, rather than by direct electromagnetic-thermal coupling within the thermal-fluid solver. Two parametric studies were performed to quantify the heat-sink effect. First, the tumor-aorta distance was varied at D = 0 mm, 4 mm, and 8.5 mm to assess how vessel proximity affects temperature elevation and ablation zone formation. Second, at each tumor-aorta distance, three blood-flow conditions were compared: no blood, stagnant blood V = 0 m/s, and normal aortic blood flow V=0.65 m/s. This comparison enabled the heat-sink effect of blood flow to be independently evaluated. The results highlight the clinical need for simulation-based treatment planning in patients with tumors located close to major vessels.
