神经系统疾病患者的牵引错觉
Pulling Illusion in Individuals with Neurological Disorders
- National Institute of Advanced Industrial Science and Technology (AIST)（产业技术综合研究所）
- Ibaraki Prefectural University of Health Sciences（茨城健康科学大学）
- Hiroshima University（广岛大学）
机构由 AI 辅助整理，请以论文原文为准。
AI总结：
本研究通过神经系统疾病患者实验，发现牵引错觉依赖于超出基本振动检测的知觉加工，而非仅外周敏感性，为理解其机制提供新证据。
AI中文摘要：
由非对称振动刺激诱发的牵引错觉因其在康复和感觉评估中的潜在应用而受到关注。然而，牵引错觉的潜在机制仍不清楚。本研究探讨了一个核心问题：仅凭外周振动触觉敏感性是否足以产生错觉，还是需要超出基本振动检测之外的加工过程。神经系统疾病可能涉及神经系统不同层面的损伤，为检验这一问题提供了机会。因此，我们评估了25名患有影响从外周到中枢不同层面神经系统的多种神经系统疾病参与者的牵引错觉方向辨别能力和指尖振动检测阈值。聚类分析识别出对比鲜明的特征：尽管振动检测阈值升高，但方向辨别能力较高；以及尽管阈值相对较低至中等，但方向辨别能力处于随机水平。在广义线性混合模型中，运动相关体征（包括偏瘫和震颤）与方向辨别能力呈稳健负相关，而振动检测阈值与能力无稳健关联。此外，在偏瘫参与者中，受影响侧的方向辨别能力接近随机水平，而未受影响侧接近100%，尽管两侧的刺激幅度均远高于测得的振动检测阈值。总体而言，这些发现表明牵引错觉依赖于超出基本振动检测的知觉加工过程，通过该过程，非对称振动被体验为方向性牵引。
英文摘要：
The pulling illusion induced by asymmetric vibration stimuli has attracted attention for its potential applications in rehabilitation and sensory assessment. However, the underlying mechanism of the pulling illusion remains unclear. This study addressed the central question of whether peripheral vibrotactile sensitivity alone is sufficient for the illusion to emerge or whether processing beyond basic vibration detection is also required. Neurological disorders can involve impairments at different levels of the nervous system, providing an opportunity to examine this question. Accordingly, we evaluated directional discrimination performance for the pulling illusion and fingertip vibration detection thresholds in 25 participants with diverse neurological disorders affecting different levels of the nervous system, from peripheral to central. Clustering analysis identified contrasting profiles, with high directional discrimination performance despite elevated vibration detection thresholds and chance-level performance despite relatively low-to-intermediate thresholds. In the generalized linear mixed model, motor-related signs, including hemiplegia and tremor, showed a robust negative association with directional discrimination performance, whereas vibration detection threshold was not robustly associated with performance. Furthermore, in participants with hemiplegia, directional discrimination performance was around chance level on the affected side and close to 100% on the unaffected side, despite stimulus amplitudes well above the measured vibration detection thresholds on both sides. Collectively, these findings suggest that the pulling illusion depends on perceptual processing beyond basic vibration detection, through which asymmetric vibration is experienced as directional pulling.
