arXiv 2609.02337physics.ins-det

面向靶碎裂的高分辨率探测：用于质子治疗应用的TEA敏化NIT

Toward High-Resolution Detection of Target Fragmentation: TEA-Sensitized NIT for Proton Therapy Applications

V. Boccia, T. Asada, A. Alexandrov, G. Ambrosi, S. Argirò, M. Barbanera, N. Bartosik, G. Battistoni, A. Bigot, M. G. Bisogni, G. Butella, F. Cavanna, P. Cerello… 展开作者

V. Boccia, T. Asada, A. Alexandrov, G. Ambrosi, S. Argirò, M. Barbanera, N. Bartosik, G. Battistoni, A. Bigot, M. G. Bisogni, G. Butella, F. Cavanna, P. Cerello, E. Ciarrocchi, N. D'Ambrosio, G. De Lellis, A. Di Crescenzo, B. Di Ruzza, M. Dondi, M. Donetti, Y. Dong, M. Durante, R. Faccini, V. Ferrero, C. Finck, E. Fiorina, M. Francesconi, M. Franchini, G. Franciosini, L. Galli, A. Iuliano, K. Kanxheri, B. Kharpuse, M. Kimura, S. Kodaira, A. C. Kraan, A. Lauria, E. Lopez Torres, T. Maggipinto, M. Magi, A. Manna, M. Marafini, S. Masci, M. Massa, C. Massimi, I. Mattei, S. Mazzolani, A. Mengarelli, A. Mereghetti, R. Mirabelli, A. Moggi, M. C. Montesi, M. C. Morone, M. Morrocchi, S. Muraro, T. Naka, N. Pastrone, V. Patera, F. Pennazio, C. Pisanti, P. Placidi, M. Pullia, F. Quattrini, S. Rabaglia, L. Ramello, C. A. Reidel, R. Ridolfi, L. Rocchetti, L. Sabatini, L. Salvi, C. Sanelli, A. Sarti, O. Sato, S. Savazzi, A. Schiavi, C. Schuy, E. Scifoni, L. Servoli, G. Silvestre, M. Sitta, K. Someya, B. Spadavecchia, R. Spighi, E. Spiriti, L. Testa, V. Tioukov, S. Tomassini, F. Tommasino, M. Toppi, G. Traini, A. Trigilio, G. Ubaldi, S. Valentinetti, M. Vanstalle, M. Villa, U. Weber, R. Zarrella, A. Zoccoli, G. Galati

首次发表 2026-09-04

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中文总结 AI 辅助

本研究针对质子治疗相关靶碎裂探测中NIT的径迹重建效率问题，采用TEA等敏化方法结合GR-1显影剂提升其灵敏度，经多类射线辐照验证了探测器响应性能。

中文摘要 AI 辅助

纳米成像径迹探测器（Nano Imaging Trackers，NIT）是一种细粒度核乳胶，具备亚微米级空间分辨率的带电粒子径迹探测能力。DAMON（靶碎裂直接测量）实验近期利用NIT在直接运动学条件下探测与质子治疗相关的靶碎裂事件。这些测量结果显示，小晶体尺寸虽能提供高空间分辨率，但会限制初级质子径迹和高能次级质子的重建效率。本研究报告了通过替代化学敏化方法实现的NIT灵敏度提升，即金加硫（Au-S）和三乙醇胺（TEA）敏化，结合GR-1显影剂的使用。探测器响应通过伽马射线、碳离子和质子辐照进行评估，包括临床相关的质子能量。

英文摘要

Nano Imaging Trackers (NIT) are fine-grained nuclear emulsions capable of tracking charged particles with sub-micrometric spatial resolution. The DAMON (Direct Measurement of Target Fragmentation) experiment recently employed NIT to detect target-fragmentation events relevant to proton therapy in direct kinematics. These measurements showed that the small crystal size, while providing high spatial resolution, limits the reconstruction efficiency for primary proton tracks and high-energy secondary protons. This work reports an enhancement of NIT sensitivity achieved through alternative chemical sensitization methods, namely gold-plus-sulfur (Au-S) and triethanolamine (TEA), together with the use of the GR-1 developer. The detector response was evaluated with gamma-ray, carbon-ion and proton exposures, including clinically relevant proton energies.