AI 中文总结
该研究开发双流体分析模型，结合磁场与微极流体等，揭示微旋转动力学对溶质输运的影响，建立适用于生物流体等领域的广义理论框架。
AI 中文摘要
本研究对带有多孔层的磁流体动力学多相管流中的广义溶质弥散开展理论研究，开发了适用于生物流体与环境流体动力学的双流体分析模型。该模型包含代表红细胞旋转行为的微极（非牛顿）流体核心，以及嵌入了Brinkman和Darcy多孔结构的牛顿血浆外围，分别对应具有不同渗透率特征的糖萼层与内皮层。引入横向磁场以探究磁场诱导的载体流变化如何影响溶质定位，该研究对磁场纳米颗粒介导的药物递送具有潜在相关性。采用Sankarasubramanian与Gill的广义弥散框架，推导分析解以探究耦合轴向速度场及相关微旋转动力学如何影响溶质输运。通过布朗动力学模拟对分析预测进行独立验证，结果显示其与第零和第一输运动矩的时间演化具有极佳一致性。研究结果揭示了微旋转动力学对溶质浓度、对流系数及有效弥散的此前未被探索的影响，为生物流体输运中平动与旋转流体运动的耦合作用提供了新见解。本研究填补了文献中的重要空白，建立了连接磁场、微极流体与多孔动脉结构的广义理论框架，可应用于生物流体输运、靶向药物递送及临床工程领域。
英文摘要
This study presents a theoretical investigation of generalized solute dispersion in magnetohydrodynamic multiphase tube flow with porous layers. A two-fluid analytical model is developed for applications in biofluid and environmental fluid dynamics. The model comprises a micropolar (non-Newtonian) fluid core representing the rotational behaviour of red blood cells and a Newtonian plasma periphery embedded with Brinkman and Darcy porous structures, corresponding to the glycocalyx and endothelial layers with distinct permeability characteristics. A transverse magnetic field is incorporated to investigate how magnetic-field-induced modifications of the carrier flow influence solute localisation, with potential relevance to magnetic nanoparticle-mediated drug delivery. Using the generalised dispersion framework of Sankarasubramanian & Gill, analytical solutions are derived to investigate how the coupled axial velocity field and associated microrotational dynamics influence solute transport. The analytical predictions are independently validated through Brownian dynamics simulations, demonstrating excellent agreement for the temporal evolution of the zeroth and first transport moments. The results reveal the previously unexplored influence of microrotational dynamics on solute concentration, convection coefficients and effective dispersion, providing new insights into the coupled roles of translational and rotational fluid motion in biofluid transport. This work bridges an important gap in the literature and establishes a generalized theoretical framework linking magnetic fields, micropolar fluids and porous arterial structures for biofluid transport, targeted drug delivery and clinical engineering applications.
