发表机构
United International University（联合国际大学）
机构由 AI 辅助整理，请以论文原文为准。AI 中文总结
针对孟加拉国农村医院无电子健康记录、医生接诊量大等痛点，提出基于智能手机的轻量型检索式处方安全检查系统，旨在检测药物不良反应，开展可行性研究评估其适配性与可靠性。
AI 中文摘要
药物不良反应（ADRs）是患者伤害的一个主要且在很大程度上可预防的来源。在高收入环境中，电子健康记录存储患者的过敏史，并在开具禁忌药物时向处方医生发出警告；而在孟加拉国农村公立医院，出院患者没有此类记录，一名医生每分钟可能接诊约一名患者，且患者的严重反应史无法在就诊间留存。本文针对该场景提出并概述了一种基于智能手机的轻量型安全检查系统的评估方案：在患者登记时记录软标识符（一个电话号码）；医生开具处方后，拍摄处方图像，利用国家药物参考将品牌名解析为活性成分，再将这些成分与患者已记录的严重反应史进行匹配。该系统基于检索而非预测，且默认静默，仅在高风险匹配时发出警示，这一设计基于警示疲劳文献。我们将本研究定位为可行性研究：描述了所提出的框架及评估计划，该计划在高流量下测量工作流适配性、可用性、身份解析可靠性，以及对已知反应病例的回顾性检测。我们明确不声称其具有临床结局效应，因为严重事件的低基线发生率超出了单中心可行性研究的范畴。
英文摘要
Adverse drug reactions (ADRs) are a major, largely preventable source of patient harm. In high-income settings, electronic health records store a patient's allergy history and warn prescribers when a contraindicated drug is ordered; in rural Bangladeshi public hospitals no such record exists for outgoing patients, a single physician may see on the order of one patient per minute, and a patient's history of severe reactions does not survive between visits. This paper proposes and outlines the evaluation of a lightweight, smartphone-based safety-check system for this setting. At registration a soft identifier (a phone number) is recorded; after the physician writes a prescription, its image is captured, the brand names are resolved to active ingredients using national drug references, and the ingredients are matched against the patient's recorded severe reaction history. The system is retrieval-based rather than predictive, and is silent by default, raising a flag only for high-risk matches a design grounded in the alert-fatigue literature. We frame the work as a feasibility study: we describe the proposed framework and an evaluation plan measuring workflow fit under high volume, usability, identity-resolution reliability, and retrospective detection of known reaction cases. We explicitly do not claim a clinical-outcome effect, which the low base rate of severe events places beyond a single-site feasibility study.
CommentsThis paper is just a pre print, still in working stage, 4 pages
