AI 中文总结
该研究开发了用于高速原子力显微镜(HS-AFM)数据分析的UMEX Viewer软件套件,具备图像处理等多种功能,可用于阐明生物功能的相关研究。
AI 中文摘要
原子力显微镜(AFM)的近期技术进展催生了高速AFM(HS-AFM),该技术可实现视频速率成像,直接可视化溶液中发挥功能的生物分子的纳米级动态过程。由于HS-AFM会快速生成大量数据集,专用软件对于高效处理、组织和分析至关重要。成像速度的近期提升进一步提高了数据吞吐量,凸显了对速度更快、可用性更强的分析软件的需求。为满足这一需求,我们开发了Ultrafast Microscopy Exploration(UMEX)Viewer,这是一款用于HS-AFM数据分析的软件套件。UMEX Viewer为HS-AFM数据处理提供了集成环境,包括图像处理、漂移校正、图像与影片导出、数据管理及定量分析。这些功能使该软件已应用于近期的众多研究中。本文将阐述UMEX Viewer的核心功能,并展示其在HS-AFM数据分析中的实际应用,旨在阐明生物功能。
英文摘要
Recent technical advances in atomic force microscopy (AFM) have led to the development of high-speed AFM (HS-AFM), which enables video-rate imaging and direct visualization of the nanoscale dynamics of biomolecules functioning in solution. Because HS-AFM rapidly generates large datasets, dedicated software is essential for efficient processing, organization, and analysis. Recent improvements in imaging speed have further increased data throughput, underscoring the need for faster analysis software with improved usability. To address this need, we developed Ultrafast Microscopy Exploration (UMEX) Viewer, a software suite for HS-AFM data analysis. UMEX Viewer provides an integrated environment for HS-AFM data handling, including image processing, drift correction, image and movie export, data management, and quantitative analysis. These capabilities have enabled the software to be applied to a wide range of recent studies. In this article, we describe the core functions of UMEX Viewer and demonstrate its practical applications for HS-AFM data analysis aimed at elucidating biological functions.