用于微体积样品传感的表面液体负载下拓扑表面声波共振的实验实现
Experimental Realization of Topological Surface Acoustic Wave Resonances under Surface Liquid Loading for Micro-volume sample Sensings
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中文总结 AI 辅助
该研究设计制备了一种拓扑表面声波谐振传感器，利用拓扑界面态与谐振腔的干涉耦合，可在表面液体负载下实现微体积样品的高灵敏度浓度传感，为高性能SAW生物医学芯片提供了技术路线。
中文摘要 AI 辅助
表面声波（SAW）传感器因工作频率高、与平面微加工兼容且对表面扰动具有极高灵敏度，被广泛应用于芯片实验室和生物医学诊断领域。然而，传统SAW传感器在液体环境中工作时会出现显著的能量耗散，这会大幅降低其品质因数（Q因子）并限制传感可靠性。本文中，我们利用拓扑界面态与谐振腔之间的干涉耦合，设计并制备了一种适用于表面液体负载的拓扑SAW谐振传感器。采用半解析平面波展开-有限元法验证了能带结构。该器件仅需0.04微升的样品，即可实现NaCl和葡萄糖溶液的浓度传感，对NaCl的灵敏度高达190千赫/百分比，对葡萄糖的灵敏度为101.8千赫/百分比，浓度分辨率为0.01%。本研究为用于微体积样品分析的高性能SAW生物医学芯片提供了一条潜在的技术途径。
英文摘要
Surface acoustic wave (SAW) sensors, owing to their high operating frequencies, compatibility with planar micro-fabrication, and exceptional sensitivity to surface perturbations, are widely used in lab -on-a-chip and biomedical diagnostic applications. However, conventional SAW sensors operating in liquid environments suffer from substantial energy dissipation, which markedly reduces their quality factors (Q factors) and limits sensing reliability. Here, we design and fabricate a topological SAW resonant sensor for surface liquid loading by exploiting interference coupling between topological interface states and resonant cavities. The band structures are validated using a semi-analytical plane wave expansion-finite element method. The device requires only 0.04 uL of sample and enables concentration sensing of NaCl and glucose solutions, with sensitivities of up to 190 kHz/% for NaCl and 101.8 kHz% for glucose, respectively, and a concentration resolution of 0.01%. This work offers a potential technological route towards high-performance SAW biomedical chips for micro-volume sample analysis.
