用于动脉血压波形测量的柔性压阻纱线压力传感器
Flexible Piezoresistive Yarn Pressure Sensor for Arterial Blood Pressure Waveform Measurement
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中文总结 AI 辅助
本研究提出一种柔性压阻纱线（FPY）压力传感器，经硬件模拟器和动脉部位实验验证，其测量动脉血压（ABP）波形的相关度高，可作为ABP波形监测的创新方案，具备开发为心血管疾病诊断设备的潜力。
中文摘要 AI 辅助
动脉血压（ABP）波形包含与血流动力学状态及其与心血管疾病诊断相关的重要信息，因此连续监测ABP波形变得十分重要。目前需要一种能无创检测ABP波形形态细节且精度高的测量系统。本研究中，我们提出一种用于连续无创ABP波形测量的柔性压阻纱线（FPY）压力传感器。通过两种场景对该传感器进行实验验证：硬件模拟器上的测量和动脉部位的测量。模拟器测量旨在评估传感器检测一致波形的性能，而动脉部位测量则评估传感器测量对应心血管周期的ABP波形的性能。模拟器测量结果显示，在实际力幅值上限下，相对于参考信号，传感器的重复性、再现性和准确性的相关度量分别为0.9999±0.0002、0.9994±0.0002和0.9731±0.0027。动脉部位测量中，以3D力传感器作为参考传感器，测量得到的相关值为0.9880±0.0035。基于我们的结果，FPY压力传感器可作为监测ABP波形的创新方案，并有进一步开发为评估心血管疾病诊断设备的潜力。
英文摘要
The arterial blood pressure (ABP) waveform contains essential information concerning the hemodynamic status and its relation to the diagnosis of cardiovascular conditions. Therefore, the continuous monitoring of the ABP waveform has become important. A measurement system that offers a non-invasive approach and high accuracy in detecting morphological details of the ABP waveform is needed. In this study, we introduce a flexible piezoresistive yarn (FPY) pressure sensor for continuous non-invasive ABP waveform measurement. The sensor was experimentally validated using two scenarios: measurements on a hardware simulator and at an arterial site. The simulator measurement aimed to assess the sensor's performance in detecting consistent waveforms, while the arterial site measurements evaluated the sensor's performance in measuring ABP waveforms corresponding to the cardiovascular cycle. The simulator measurement results showed high repeatability, reproducibility, and accuracy relative to the reference signal at the upper limit of realistic force magnitude, as measured by the correlation metric: 0.9999 $\pm$ 0.0002, 0.9994 $\pm$ 0.0002, and 0.9731 $\pm$ 0.0027, respectively. The correlation value derived from measurements at the arterial site compared with measurements using a 3D force sensor as a reference sensor was 0.9880 $\pm$ 0.0035. Based on our results, the FPY pressure sensor can be used as an innovative solution for monitoring ABP waveforms and has further potential to be developed as a diagnostic device for evaluating cardiovascular conditions.
