超顺磁性Fe3O4@TiO2和Fe3O4@SiO2@TiO2核壳纳米结构的结构、光学与磁学性质
Structural, Optical and Magnetic Properties of Superparamagnetic Fe3O4@TiO2 and Fe3O4@SiO2@TiO2 CoreShell Nanostructures
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中文总结 AI 辅助
本研究合成并表征Fe3O4@TiO2和Fe3O4@SiO2@TiO2核壳纳米结构，通过多种表征手段分析其性质，证实该类结构可作为多模态癌症治疗的多功能平台，具备MRI、磁热疗及光疗等应用潜力。
中文摘要 AI 辅助
采用氧化铁核（Fe3O4）与二氧化钛壳（TiO2）构建核壳纳米结构，为多模态癌症治疗提供了极具前景的多功能平台：TiO2壳具备光响应光学性质，适用于光学成像与光疗；Fe3O4磁性核可实现磁共振成像（MRI）与磁热疗（MHT）。本研究报道了Fe3O4@TiO2及Fe3O4@SiO2@TiO2核壳纳米结构的合成与表征，通过X射线衍射（XRD）、傅里叶变换红外光谱（FTIR）、透射电子显微镜（TEM）、高分辨率扫描电子显微镜（HRSEM）、漫反射紫外-可见光谱（DRS）与超导量子干涉仪（SQUID）磁强计评估了其结构与物理性质，凸显了这类磁性核-光激活壳纳米结构在磁热疗辅助下用于多模态治疗的潜力。
英文摘要
Tailoring core-shell nanostructures using iron oxide core (Fe3O4) and titanium dioxide shell (TiO2) offer a promising multifunctional platform for multimodal cancer therapies. TiO2 shell exhibits photo-responsive optical properties suitable for optical imaging and phototherapies, while Fe3O4 magnetic core enables magnetic resonance imaging (MRI) and magnetic hyperthermia therapy (MHT). This present work reports synthesis and characterization from core-shell Fe3O4@TiO2 and Fe3O4@SiO2@TiO2 nanostructures. Structural and physical properties were evaluated using X-ray Diffraction (XRD), Fourier-Transform Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), High-Resolution Scanning Electron Microscopy (HRSEM), Diffuse UV-Vis Reflectance Spectroscopy (DRS) and SQUID magnetometry. This work highlights the potential use of magnetic (core) and optically activated (shell) nanostructures for multimodal therapies assisted by magnetic hyperthermia.
