AI 中文总结
研究跨膜离子输运中弱磁场对电流影响，构建介观平衡框架，表明磁场通过改变亚稳态输运态概率调控输运，统一解释磁增强与抑制，给出磁符号反转准则及可实验测试特征，提供定量解释框架。
AI 中文摘要
长期以来，弱磁场对跨膜离子电流的影响存在增强或抑制两种相悖情况，其物理根源未明。本文构建介观平衡框架，表明弱磁场主要改变亚稳态输运态的平衡占据概率，进而改变非平衡离子电流。磁场通过导电态的统计重分布调控输运，而非直接作用于微观离子轨迹。该机制在统一理论框架下解释了磁增强和磁抑制，并预测了由单一平衡协方差控制的磁符号反转通用准则。理论还识别出可实验测试的特征，为解释生物离子输运中的弱场磁效应提供定量框架。
英文摘要
Weak magnetic fields have long been reported to either enhance or suppress transmembrane ionic currents, yet the physical origin of these apparently contradictory responses remains unresolved. Here, we develop a mesoscopic equilibrium framework showing that weak magnetic fields primarily modify the equilibrium occupation probabilities of metastable transport states, thereby altering the resulting nonequilibrium ionic current. Rather than acting directly on microscopic ionic trajectories, magnetic fields regulate transport through the statistical redistribution of conducting states. This mechanism naturally explains both magnetic enhancement and suppression within a unified theoretical framework and predicts a universal criterion for magnetic sign reversal governed by a single equilibrium covariance. The theory further identifies experimentally testable signatures, including characteristic magnetic-field dependence and state-dependent transport modulation, providing a quantitative framework for interpreting weak-field magnetic effects in biological ionic transport.
