发表机构
Yale School of Public Health; Yale University（耶鲁大学公共卫生学院; 耶鲁大学）
机构由 AI 辅助整理，请以论文原文为准。AI 中文总结
利用“我们所有人”研究项目数据，通过多种分析方法探究环境和社会心理因素与主观认知困难的关系，发现考虑地点内变化后环境扰动关联有限，社会心理因素关联更显著，人工智能辅助分析结果与之相符。
AI 中文摘要
短期环境暴露与认知和行为结果有关，但许多报告的关联可能反映了更广泛的地理和背景差异。利用“我们所有人”研究项目（2018 - 2024年）的纵向数据，将每日天气和空气污染暴露与重复的注意力相关及主观认知结果联系起来。通过多种分析方法评估关联，并进行机器学习分析以探索潜在异质性和潜在社会心理结构。复制分析使用2024年行为风险因素监测系统（BRFSS）。结果显示，一些环境暴露措施在汇总分析中与认知结果有小关联，但考虑地点内时间变化后大多减弱。心理健康负担、孤独感和社会功能与主观认知困难持续相关且效应量更大。探索性人工智能辅助分析结果与主要纵向分析大致一致。这些发现表明，考虑地点内变化后，短期环境扰动与认知结果的关联有限，而社会心理因素似乎与主观认知负担更一致相关。
英文摘要
Short-term environmental exposures have been linked to cognitive and behavioral outcomes, although many reported associations may reflect broader geographic and contextual differences. Using longitudinal data from the All of Us Research Program (2018--2024), we linked daily weather and air-pollution exposures to repeated attention-related and subjective cognitive outcomes. Associations were evaluated using pooled, fixed-effects, lagged, and event-study analyses. Additional machine-learning analyses were conducted to explore potential heterogeneity and latent psychosocial structure. Replication analyses were performed using the 2024 Behavioral Risk Factor Surveillance System (BRFSS). Several environmental exposure measures showed small associations with cognitive outcomes in pooled analyses, but most attenuated substantially after accounting for within-location temporal variation. Mediation, sensitivity, and machine-learning analyses yielded similar conclusions. In contrast, mental-health burden, loneliness, and social functioning were consistently associated with subjective cognitive difficulty and exhibited substantially larger effect sizes than environmental exposures. Similar patterns were observed in BRFSS. Exploratory AI-assisted analyses yielded findings broadly consistent with the primary longitudinal analyses. These findings suggest that short-term environmental perturbations may have limited associations with cognitive outcomes after accounting for within-location variation, whereas psychosocial factors appear to be more consistently associated with subjective cognitive burden.
Comments30 pages, 10 figures
