AI 中文总结
该研究针对不同 Hologic DXA 扫描仪模型，通过重复采集数据，评估 3D-DXA 参数的短期精度及最小显著变化，得出不同参数的 LSC 值范围，其精度误差在各数据集间有适度变化，结果有助于解释相关骨密度纵向变化。
AI 中文摘要
3D-DXA 可从标准 DXA 扫描中提供特定部位的髋部测量。本研究使用五个临床 Hologic DXA 扫描仪数据集的重复采集来评估 3D-DXA 参数的短期精度。在五个临床中心，用不同型号扫描仪对每位受试者进行两次重复扫描并重新定位。用软件获取常规和 3D 参数，以 RMS-SD 和 RMS-CV 表示精度误差，计算 95%置信水平的 LSC。结果显示不同参数的 LSC 值范围，3D-Shaper 参数精度误差在五个临床数据集间有适度变化，与已发表数据大致可比。这些 LSC 值有助于解释 Hologic 扫描仪上相关骨密度的纵向变化。
英文摘要
3D-DXA provides volumetric and compartment-specific hip measurements from standard DXA scans. However, for reliable longitudinal interpretation, establishing scanner-specific short-term precision data is essential. This study assessed the short-term precision of 3D-DXA-derived parameters using repeated acquisitions from five clinical Hologic DXA scanner datasets. Duplicate hip DXA acquisitions were collected at five clinical centers using two Horizon Wi scanners, two Horizon A scanners, and one Discovery W scanner. Each subject was scanned twice with complete repositioning between acquisitions. Conventional total hip and femoral neck aBMD were obtained using APEX software, and 3D-Shaper software was used to derive integral vBMD, trabecular vBMD, and cortical sBMD. Precision error was expressed as RMS-SD and RMS-CV, and LSC was calculated at the 95% confidence level. For total hip aBMD, absolute LSC values ranged from 0.018 to 0.037 g/cm$^2$. Femoral neck aBMD showed higher error, with LSC values ranging from 0.031 to 0.049 g/cm$^2$. For 3D-DXA parameters, absolute LSC values ranged from 9.955 to 17.859 mg/cm$^2$ for integral vBMD, 8.662 to 18.487 mg/cm$^2$ for trabecular vBMD, and 4.444 to 8.875 mg/cm$^2$ for cortical sBMD. Precision errors for 3D-Shaper parameters varied moderately across the five clinical datasets. Short-term precision of 3D-Shaper-derived measurements was broadly comparable with previously published precision data. The LSC values reported here can support interpretation of longitudinal changes in integral vBMD, trabecular vBMD, and cortical sBMD on Hologic scanners.
