作为光自适应人工虹膜的数字可编程光致变色水凝胶隐形眼镜
Digitally Programmable Photochromic Hydrogel Contact Lenses as Light-Adaptive Artificial Irises
浏览论文内容
中文总结 AI 辅助
研究旨在研发光自适应软性光学器件，核心方法是将光致变色染料嵌入水凝胶，用DMD光刻编码梯度。贡献是制成模拟人虹膜功能的光自适应隐形眼镜，具快速可逆光响应、稳定光致变色及适合应用的特性。
中文摘要 AI 辅助
过度暴露于紫外线辐射会引发一系列眼部疾病，这促使人们研发能动态调节入射光的软性光学器件。人眼中，虹膜通过调节瞳孔大小来控制视网膜辐照度以适应环境光照。本文展示了一种基于光致变色隐形眼镜的人工虹膜，它通过具有固有紫外线阻挡功能的光学传输的可逆、空间可编程调制来模拟这种生物光适应机制。光致变色染料嵌入生物相容性水凝胶基质中，同时使用基于数字微镜器件（DMD）的灰度紫外光刻对交联网络进行图案化，以编码染料切换中受控的径向梯度。该方法产生类似虹膜的衰减曲线，模拟瞳孔依赖的光调节，同时实现可定制的虹膜几何形状和传输模式。所得镜片表现出快速且可逆的紫外线诱导变暗，具有位置依赖的动力学，能够连续调节透射光。光响应在重复激活循环中保持稳定，无明显疲劳。图案化镜片保持机械稳定性、可控膨胀性和适合隐形眼镜应用的润湿性。该平台结合了可编程光致变色和水凝胶光学，实现了模拟人虹膜关键功能的光自适应镜片。
英文摘要
Excessive exposure to ultraviolet (UV) radiation is associated with a range of ocular pathologies, motivating the development of soft optical devices that can dynamically regulate incident light. In the human eye, this adaptive optical functionality is performed by the iris, which modulates pupil size to control retinal irradiance in response to ambient illumination. Here we present a photochromic contact lens based artificial iris that mimics this biological light-adaptation mechanism through reversible, spatially programmable modulation of optical transmission with intrinsic UV blocking. Photochromic dyes are embedded within a biocompatible hydrogel matrix, while the cross-linked network is patterned using a digital micromirror device (DMD)based grayscale UV lithography to encode controlled radial gradients in dye switching. This approach generates iris-like attenuation profiles that emulate pupil-dependent light regulation while enabling customizable iris geometries and transmission patterns. The resulting lenses exhibit rapid and reversible UV-induced darkening with position-dependent kinetics, enabling continuous modulation of transmitted light. The photoresponse remains stable over repeated activation cycles without measurable fatigue. The patterned lenses maintain mechanical stability, controlled swelling, and wettability suitable for contact lens applications. This platform combines programmable photochromism and hydrogel optics to enable light-adaptive lenses that mimic key functions of the human iris.
