用于快速高灵敏度高光谱成像的无扫描量子傅里叶变换中红外光谱技术
Scanless quantum Fourier-transform mid-infrared spectroscopy for rapid high-sensitivity hyperspectral mapping
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中文总结 AI 辅助
研究利用无扫描量子FTIR技术，通过纠缠光子计量原理及频域测量，结合重建算法，突破传统FTIR局限。相比传统方法信噪比优势明显，实现快速高光谱成像，空间与光谱分辨率高，能快速获取多种样品高质量单像素光谱。
中文摘要 AI 辅助
傅里叶变换红外（FTIR）光谱是用于定性和定量化学分析的成熟技术。然而，传统FTIR系统依赖基于中红外扫描的相干函数时域测量，其信噪比和测量速度受设计限制。本文展示了一种无扫描量子FTIR（sQFTIR）技术，利用纠缠光子的计量原理规避传统FTIR系统的固有局限。该方法利用传感范式的干涉性质，通过静态、低增益非线性干涉仪进行频域测量。使用稳健重建算法从近红外测量中检索时域信号并重建中红外光谱（3000$~$cm$^{-1}$至2380$~$cm$^{-1}$）。sQFTIR协议无需光学延迟扫描，利用相关域之间的固有映射。理论部分评估了该方法相对于传统基于扫描的时域测量的固有信噪比优势，相差26.8 dB（因子为21.8）。基于该方案的增强灵敏度，展示了基于sQFTIR的快速高光谱成像，空间分辨率为12.3$~\mu$m，光谱分辨率低至8$~$cm$^{-1}$。对人体结肠组织、微塑料以及由聚丙烯和乙烯乙烯醇组成的多层聚合物样品进行高光谱成像，能在10$~$ms的采集时间内获得高质量单像素光谱。
英文摘要
Fourier-transform infrared (FTIR) spectroscopy is a well-established technique for qualitative and quantitative chemical analysis. Classical FTIR systems rely, however, on direct mid-infrared (mid-IR) scan-based time-domain measurements of coherence functions; thus, the signal-to-noise ratio and measurement speed are constrained by design. In this paper, we demonstrate a scanless quantum FTIR (sQFTIR) technique that exploits principles of metrology with entangled photons to circumvent the limitations inherent to classical FTIR systems. The approach exploits the interferometric nature of the sensing paradigm and relies on frequency-domain measurements performed with a static, low-gain nonlinear interferometer. A robust reconstruction algorithm is used to retrieve time-domain signals and reconstruct respective mid-infrared (mid-IR) spectra (3000$~$cm$^{-1}$ to 2380$~$cm$^{-1}$) from near-IR measurements (approx. 780$~$nm to 820$~$nm). The suggested sQFTIR protocol eliminates the need for optical delay scanning and leverages inherent mapping between the related domains. In the theoretical section, we evaluate the intrinsic signal-to-noise advantage of the proposed method over conventional scan-based time-domain measurements; a difference of 26.8 dB (factor of 21.8) is demonstrated. Building on the enhanced sensitivity of the scheme, we demonstrate rapid sQFTIR-based hyperspectral imaging with a spatial resolution of 12.3$~μ$m and a spectral resolution down to 8$~$cm$^{-1}$. Hyperspectral mapping of human colon tissue, microplastics, and multilayer polymer samples composed of polypropylene and ethylene vinyl alcohol yield high-quality single-pixel spectra with acquisition times down to 10$~$ms.
