论痴呆症患者大脑连接性的增强与减弱
On the Increased and Decreased Connectivity of the Demented Human Brain
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中文总结 AI 辅助
利用OASIS - 3数据集研究衰老和痴呆大脑，发现海马体和颞叶在痴呆症中连接性降低，而楔前叶、楔叶和脑岛中的精细结构在痴呆症中连接性更高。
中文摘要 AI 辅助
随着脑成像技术的巨大进步，有大量数据可用于研究衰老和痴呆的大脑。在本研究中，我们应用OASIS - 3数据集来识别人类灰质的小区域，这些区域在痴呆和衰老过程中具有较高或较低的结构连接性。正如预期的那样，我们发现海马体和颞叶的精细结构在痴呆症中显示出连接性降低。更令人惊讶的是，楔前叶、楔叶和脑岛中的精细结构在痴呆症中比健康状态下显示出更高的连接性。
英文摘要
With major advances in cerebral imaging techniques, a large amount of data is available for studying the aging and demented brain. In this contribution, we apply the OASIS-3 dataset to identify small areas of human gray matter with higher or lower structural connectivity in dementia. As was anticipated, we have found that finer structures of the hippocampus and the temporal lobe have decreased connectivity in dementia. More surprisingly, the precuneus, the cuneus, and some finer structures of the insula, the paracentral lobule, and the precentral and paracentral gyri showed higher connectivity in dementia than in healthy subjects.
发表机构
- ELTE Eötvös Loránd University（罗兰大学）
- Uratim Ltd.（Uratim有限公司）
机构由 AI 辅助整理，请以论文原文为准。
