Anatomical landmark detection is a fundamental task in medical image analysis supporting a wide range of diagnostic and interventional workflows. Although recent methods have achieved sub-millimetric localisation, accuracy alone is not sufficient for clinical deployment, requiring reliability and robustness in prediction. Despite its clinical relevance, the impact of representation learning in this context is still underexplored. In this work, we introduce CDPM-align, a multi-scale guidance-aligned conditional diffusion pre-training for anatomical landmark detection. Our experimental setup focuses on a few images and a few annotation regimes. Specifically, we employ three popular heterogeneous small-scale benchmark datasets for representation learning via conditional generative pre-training. Furthermore, we consider low-annotation scenarios for the downstream task of landmark detection, with 10 and 25 annotated images, reflecting realistic trade-offs between clinical effort and resource constraints for annotations. Our results confirm that generative pre-training enables the model to learn a robust representation. This improves both accuracy and uncertainty on the downstream tasks, advancing towards safe and efficient clinical deployment.
University of Science and Technology of China（中国科学技术大学）；Suzhou Institute for Advanced Research, University of Science and Technology of China（中国科学技术大学苏州高等研究院）
Detecting anatomical landmarks in medical images plays an essential role in understanding the anatomy and planning automated processing. In recent years, a variety of deep neural network methods have been developed to detect landmarks automatically. However, all of those methods are unary in the sense that a highly specialized network is trained for a single task say associated with a particular anatomical region. In this work, for the first time, we investigate the idea of "You Only Learn Once (YOLO)" and develop a universal anatomical landmark detection model to realize multiple landmark det…
The University of Hong Kong（香港大学）；ShanghaiTech University（上海科技大学）；Max Planck Institute for Informatics（马克斯·普朗克信息学研究所）；South China University of Technology（华南理工大学）
Well-annotated medical images are costly and sometimes even impossible to acquire, hindering landmark detection accuracy to some extent. Semi-supervised learning alleviates the reliance on large-scale annotated data by exploiting the unlabeled data to understand the population structure of anatomical landmarks. The global shape constraint is the inherent property of anatomical landmarks that provides valuable guidance for more consistent pseudo labelling of the unlabeled data, which is ignored in the previously semi-supervised methods. In this paper, we propose a model-agnostic shape-regulated…
University of Electronic Science and Technology of China（电子科技大学）
Localization of anatomical landmarks is essential for clinical diagnosis, treatment planning, and research. In this paper, we propose a novel deep network, named feature aggregation and refinement network (FARNet), for the automatic detection of anatomical landmarks. To alleviate the problem of limited training data in the medical domain, our network adopts a deep network pre-trained on natural images as the backbone network and several popular networks have been compared. Our FARNet also includes a multi-scale feature aggregation module for multi-scale feature fusion and a feature refinement …
Mask-HybridGNet: Graph-based segmentation with emergent anatomical correspondence from pixel-level supervision
Biomedical Image Technologies, ETSI Telecomunicación, Universidad Politécnica de Madrid, Madrid, Spain（生物医学影像技术，电信工程学院，马德里理工大学，马德里，西班牙）；IHU PRISM National Precision Medicine Center in Oncology, Cancer Data Science Unit, CentraleSupélec, Gustave Roussy, INSERM, Université Paris-Saclay, Gif-sur-Yvette, France（IHU PRISM国家精准医学中心（肿瘤学），癌症数据科学单元，中央圣艾尔布兰，格斯塔夫·罗西，国家医学研究所，巴黎-萨克雷大学，法国）
UAE: Universal Anatomical Embedding on Multi-modality Medical Images
National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology, School of Computer Science and Engineering, Northwestern Polytechnical University（西北工业大学计算机科学与工程学院，空天地海一体化大数据应用技术国家工程实验室）；Department of Electronic Engineering, The Chinese University of Hong Kong（香港中文大学电子工程系）；Beijing United Family Hospital（北京和睦家医院）；The First Affiliated Hospital, Zhejiang University（浙江大学医学院附属第一医院）；Peking Union Medical College Hospital（北京协和医院）
The detection of anatomical landmarks is a vital step for medical image analysis and applications for diagnosis, interpretation and guidance. Manual annotation of landmarks is a tedious process that requires domain-specific expertise and introduces inter-observer variability. This paper proposes a new detection approach for multiple landmarks based on multi-agent reinforcement learning. Our hypothesis is that the position of all anatomical landmarks is interdependent and non-random within the human anatomy, thus finding one landmark can help to deduce the location of others. Using a Deep Q-Net…
H3DE-Net: Efficient and Accurate 3D Landmark Detection in Medical Imaging
School of Computer Science USTC（计算机科学学院 中国科学技术大学）；School of Computer Science（计算机科学学院）；Shanghai Jiao Tong University（上海交通大学）；ShanghaiTech University（上海科技大学）；Sciences College（科学学院）；School of Information Science, NENU（信息科学学院 南京师范大学）；Technical University of Munich (TUM)（慕尼黑技术大学）；Stanford University（斯坦福大学）
FM-OSD: Foundation Model-Enabled One-Shot Detection of Anatomical Landmarks
The Chinese University of Hong Kong（香港中文大学）；Massachusetts General Hospital（麻省总医院）；Harvard Medical School（哈佛医学院）；Huawei Noah’s Ark Lab（华为诺亚方舟实验室）；Massachusetts General Brigham（麻省总医院布里格姆医疗系统）；Institute of Medical Intelligence and XR, The Chinese University of Hong Kong（香港中文大学医学智能与XR研究所）
University of Science and Technology of China（中国科学技术大学）
Accurate anatomical landmark detection plays an increasingly vital role in medical image analysis. Although existing methods achieve satisfying performance, they are mostly based on CNN and specialized for a single domain say associated with a particular anatomical region. In this work, we propose a universal model for multi-domain landmark detection by taking advantage of transformer for modeling long dependencies and develop a domain-adaptive transformer model, named as DATR, which is trained on multiple mixed datasets from different anatomies and capable of detecting landmarks of any image …
HYATT-Net is Grand: A Hybrid Attention Network for Performant Anatomical Landmark Detection
Suzhou Institute for Advanced Research, University of Science and Technology of China (USTC)（中国科学技术大学苏州高等研究院）；School of Computer Science and Technology, University of Science and Technology of China (USTC)（中国科学技术大学计算机科学与技术学院）；School of Information Science and Technology, Eastern Institute of Technology (EIT)（宁波东方理工大学信息科学与技术学院）；Stanford University（斯坦福大学）
Automatic and accurate detection of anatomical landmarks is an essential operation in medical image analysis with a multitude of applications. Recent deep learning methods have improved results by directly encoding the appearance of the captured anatomy with the likelihood maps (i.e., heatmaps). However, most current solutions overlook another essence of heatmap regression, the objective metric for regressing target heatmaps and rely on hand-crafted heuristics to set the target precision, thus being usually cumbersome and task-specific. In this paper, we propose a novel learning-to-learn frame…
Image Sciences Institute（影像科学研究所）；University Medical Center Utrecht（乌得勒支大学医学中心）；Department of Radiology（放射科）
Fast and accurate anatomical landmark detection can benefit many medical image analysis methods. Here, we propose a method to automatically detect anatomical landmarks in medical images. Automatic landmark detection is performed with a patch-based fully convolutional neural network (FCNN) that combines regression and classification. For any given image patch, regression is used to predict the 3D displacement vector from the image patch to the landmark. Simultaneously, classification is used to identify patches that contain the landmark. Under the assumption that patches close to a landmark can…
Deploying the idea of long-term cumulative return, reinforcement learning has shown remarkable performance in various fields. We propose a formulation of the landmark localization in 3D medical images as a reinforcement learning problem. Whereas value-based methods have been widely used to solve similar problems, we adopt an actor-critic based direct policy search method framed in a temporal difference learning approach. Successful behavior learning is challenging in large state and/or action spaces, requiring many trials. We introduce a partial policy-based reinforcement learning to enable so…
Centrum Wiskunde & Informatica（数学与计算机科学国家研究所）；Amsterdam UMC, University of Amsterdam（阿姆斯特丹大学阿姆斯特丹大学医学中心）；Delft University of Technology（代尔夫特理工大学）
Anatomical landmark correspondences in medical images can provide additional guidance information for the alignment of two images, which, in turn, is crucial for many medical applications. However, manual landmark annotation is labor-intensive. Therefore, we propose an end-to-end deep learning approach to automatically detect landmark correspondences in pairs of two-dimensional (2D) images. Our approach consists of a Siamese neural network, which is trained to identify salient locations in images as landmarks and predict matching probabilities for landmark pairs from two different images. We t…
Institute of High Performance Computing, A*STAR（新加坡科技研究局高性能计算研究所）；Singapore Eye Research Institute（新加坡眼科研究所）；Singapore National Eye Centre（新加坡全国眼科中心）；Yong Loo Lin School of Medicine, NUS（新加坡国立大学杨潞龄医学院）
Localizing anatomical landmarks are important tasks in medical image analysis. However, the landmarks to be localized often lack prominent visual features. Their locations are elusive and easily confused with the background, and thus precise localization highly depends on the context formed by their surrounding areas. In addition, the required precision is usually higher than segmentation and object detection tasks. Therefore, localization has its unique challenges different from segmentation or detection. In this paper, we propose a zoom-in attentive network (ZIAN) for anatomical landmark loc…
Accurate detection of anatomical landmarks is an essential step in several medical imaging tasks. We propose a novel communicative multi-agent reinforcement learning (C-MARL) system to automatically detect landmarks in 3D brain images. C-MARL enables the agents to learn explicit communication channels, as well as implicit communication signals by sharing certain weights of the architecture among all the agents. The proposed approach is evaluated on two brain imaging datasets from adult magnetic resonance imaging (MRI) and fetal ultrasound scans. Our experiments show that involving multiple coo…
University Medical Center Utrecht（乌得勒支大学医学中心）；Amsterdam UMC, University of Amsterdam（阿姆斯特丹大学阿姆斯特丹医学中心）；University of Twente（特文特大学）；Wageningen University（瓦赫宁根大学）
In this study, we propose a fast and accurate method to automatically localize anatomical landmarks in medical images. We employ a global-to-local localization approach using fully convolutional neural networks (FCNNs). First, a global FCNN localizes multiple landmarks through the analysis of image patches, performing regression and classification simultaneously. In regression, displacement vectors pointing from the center of image patches towards landmark locations are determined. In classification, presence of landmarks of interest in the patch is established. Global landmark locations are o…
The success of deep learning methods relies on the availability of a large number of datasets with annotations; however, curating such datasets is burdensome, especially for medical images. To relieve such a burden for a landmark detection task, we explore the feasibility of using only a single annotated image and propose a novel framework named Cascade Comparing to Detect (CC2D) for one-shot landmark detection. CC2D consists of two stages: 1) Self-supervised learning (CC2D-SSL) and 2) Training with pseudo-labels (CC2D-TPL). CC2D-SSL captures the consistent anatomical information in a coarse-t…
UOD: Universal One-shot Detection of Anatomical Landmarks
School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China（生物医学工程学院，生命科学与医学系，科学技术大学）；Suzhou Institute for Advanced Research, University of Science and Technology of China（苏州先进研究院，科学技术大学）；Key Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS), Institute of Computing Technology, CAS（中国科学院智能信息处理重点实验室，计算技术研究所，中国科学院）；Department of Radiology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences（放射科，广东省人民医院，广东省医学科学院）；Guangdong Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences（广东省人工智能在医学影像分析与应用重点实验室，广东省人民医院，广东省医学科学院）
本文提出 UOD 框架，通过领域自适应卷积与 transformer 与领域共享模块，在每域仅一个标注样本的条件下实现跨头、手、胸多领域 X 射线标志点检测，并达到最先进性能。
Radiological imaging of prostate is becoming more popular among researchers and clinicians in searching for diseases, primarily cancer. Scans might be acquired at different times, with patient movement between scans, or with different equipment, resulting in multiple datasets that need to be registered. For this issue, we introduce a registration method using anatomical feature-guided mutual information. Prostate scans of the same patient taken in three different orientations are first aligned for the accurate detection of anatomical features in 3D. Then, our pipeline allows for multiple modal…
The various speech sounds of a language are obtained by varying the shape and position of the articulators surrounding the vocal tract. Analyzing their variations is crucial for understanding speech production, diagnosing speech disorders and planning therapy. Identifying key anatomical landmarks of these structures on medical images is a pre-requisite for any quantitative analysis and the rising amount of data generated in the field calls for an automatic solution. The challenge lies in the high inter- and intra-speaker variability, the mutual interaction between the articulators and the mode…
SAM: Self-supervised Learning of Pixel-wise Anatomical Embeddings in Radiological Images
Alibaba Group DAMO Academy（阿里巴巴集团达摩院）；PAII Inc.（PAII公司）；Ping An Insurance (Group) Company of China, Ltd.（中国平安保险（集团）股份有限公司）；Beijing United Family Hospital（北京和睦家医院）
CABLD: Contrast-Agnostic Brain Landmark Detection with Consistency-Based Regularization
Department of Computer Science and Software Engineering, Concordia University（计算机科学与软件工程系，康科迪亚大学）；Department of Electrical and Computer Engineering, Concordia University（电气与计算机工程系，康科迪亚大学）
Shanghai Jiao Tong University（上海交通大学）；University of Sydney（悉尼大学）；Ruijin Hospital, Shanghai Jiao Tong University School of Medicine（上海交通大学医学院瑞金医院）
Motion estimation is a fundamental step in dynamic medical image processing for the assessment of target organ anatomy and function. However, existing image-based motion estimation methods, which optimize the motion field by evaluating the local image similarity, are prone to produce implausible estimation, especially in the presence of large motion. In this study, we provide a novel motion estimation framework of Dense-Sparse-Dense (DSD), which comprises two stages. In the first stage, we process the raw dense image to extract sparse landmarks to represent the target organ anatomical topology…
Skolkovo Institute of Science and Technology（斯科尔科沃科学技术研究院）；Artificial Intelligence Research Institute (AIRI)（人工智能研究所（AIRI））；Institute for Information Transmission Problems（信息传输问题研究所）；Moscow Institute of Physics and Technology（莫斯科物理技术学院）
Adaptive Query Prompting for Multi-Domain Landmark Detection
School of Computer Science and Technology, Guangdong University of Technology（广东技术大学计算机科学与技术学院）；School of Automation, Guangdong University of Technology（广东技术大学自动化学院）；Faculty of Applied Sciences, Macao Polytechnic University（澳门 polytechnic university 应用科学学院）；School of Information Science and Technology, Guangdong University of Foreign Studies（广东外语外贸大学信息科学与技术学院）；School of Computer Science and Engineering, Huizhou University（惠州市大学计算机科学与工程学院）
Southern University of Science and Technology（南方科技大学）；The Chinese University of Hong Kong（香港中文大学）；Air Force Medical Center, PLA（中国人民解放军空军特色医学中心）
Colonoscopy is a standard imaging tool for visualizing the entire gastrointestinal (GI) tract of patients to capture lesion areas. However, it takes the clinicians excessive time to review a large number of images extracted from colonoscopy videos. Thus, automatic detection of biological anatomical landmarks within the colon is highly demanded, which can help reduce the burden of clinicians by providing guidance information for the locations of lesion areas. In this article, we propose a novel deep learning-based approach to detect biological anatomical landmarks in colonoscopy videos. First, …
MedSapiens: Taking a Pose to Rethink Medical Imaging Landmark Detection
The Hong Kong University of Science and Technology（香港科技大学）；The University of Hong Kong（香港大学）；Erasmus MC（埃因霍温麦斯学院）；Medical University of Innsbruck（因斯布鲁克医科大学）；University of Barcelona（巴塞罗那大学）
Canon Medical Research Europe（佳能医疗欧洲研究中心）；Queen Elizabeth University Hospital（伊丽莎白女王大学医院）；University of Glasgow（格拉斯哥大学）
We present an efficient neural network method for locating anatomical landmarks in 3D medical CT scans, using atlas location autocontext in order to learn long-range spatial context. Location predictions are made by regression to Gaussian heatmaps, one heatmap per landmark. This system allows patchwise application of a shallow network, thus enabling multiple volumetric heatmaps to be predicted concurrently without prohibitive GPU memory requirements. Further, the system allows inter-landmark spatial relationships to be exploited using a simple overdetermined affine mapping that is robust to de…
University of Oulu（奥卢大学）；Oulu University Hospital（奥卢大学医院）；Aalto University（阿尔托大学）
This paper addresses the challenge of localization of anatomical landmarks in knee X-ray images at different stages of osteoarthritis (OA). Landmark localization can be viewed as regression problem, where the landmark position is directly predicted by using the region of interest or even full-size images leading to large memory footprint, especially in case of high resolution medical images. In this work, we propose an efficient deep neural networks framework with an hourglass architecture utilizing a soft-argmax layer to directly predict normalized coordinates of the landmark points. We provi…
Deep Learning-based Alignment Measurement in Knee Radiographs
Division of Informatics, Imaging and Data Sciences, The University of Manchester（信息学与数据科学系，曼彻斯特大学）；Northern Care Alliance NHS Foundation Trust（北护理联盟国家健康服务信托基金）；Department of Trauma and Orthopaedics, Stockport NHS Foundation Trust（创伤与骨科部门，史托波特国家健康服务信托基金）；School of Health and Society, University of Salford（健康与社会学院，萨尔福德大学）；School of Biological Sciences, The University of Manchester（生物科学学院，曼彻斯特大学）；Research Unit of Health Sciences and Technology, University of Oulu（健康科学与技术研究单位，奥卢大学）
The Chinese University of Hong Kong（香港中文大学）；Massachusetts Institute of Technology（麻省理工学院）
In medical imaging, surface registration is extensively used for performing systematic comparisons between anatomical structures, with a prime example being the highly convoluted brain cortical surfaces. To obtain a meaningful registration, a common approach is to identify prominent features on the surfaces and establish a low-distortion mapping between them with the feature correspondence encoded as landmark constraints. Prior registration works have primarily focused on using manually labeled landmarks and solving highly nonlinear optimization problems, which are time-consuming and hence hin…
University of Basel（巴塞尔大学）；University Hospital Basel（巴塞尔大学医院）；MIAC AG
We present an automated method for localizing an anatomical landmark in three-dimensional medical images. The method combines two recurrent neural networks in a coarse-to-fine approach: The first network determines a candidate neighborhood by analyzing the complete given image volume. The second network localizes the actual landmark precisely and accurately in the candidate neighborhood. Both networks take advantage of multi-dimensional gated recurrent units in their main layers, which allow for high model complexity with a comparatively small set of parameters. We localize the medullopontine …
3D anatomical landmarks play an important role in health research. Their automated prediction/localization thus becomes a vital task. In this paper, we introduce a deformation method for 3D anatomical landmarks prediction. It utilizes a source model with anatomical landmarks which are annotated by clinicians, and deforms this model non-rigidly to match the target model. Two constraints are introduced in the optimization, which are responsible for alignment and smoothness, respectively. Experiments are performed on our dataset and the results demonstrate the robustness of our method, and show t…
X-ray image guidance enables percutaneous alternatives to complex procedures. Unfortunately, the indirect view onto the anatomy in addition to projective simplification substantially increase the task-load for the surgeon. Additional 3D information such as knowledge of anatomical landmarks can benefit surgical decision making in complicated scenarios. Automatic detection of these landmarks in transmission imaging is challenging since image-domain features characteristic to a certain landmark change substantially depending on the viewing direction. Consequently and to the best of our knowledge,…
Institute for Signals, Systems and Computational Intelligence, sinc(i) CONICET-UNL（信号、系统与计算智能研究所，sinc(i) 阿根廷国家科学技术研究委员会-国立利托拉尔大学）；Hospital Italiano de Buenos Aires（布宜诺斯艾利斯意大利医院）；Universidad Tecnológica Nacional（国立技术大学）
Anatomical segmentation is a fundamental task in medical image computing, generally tackled with fully convolutional neural networks which produce dense segmentation masks. These models are often trained with loss functions such as cross-entropy or Dice, which assume pixels to be independent of each other, thus ignoring topological errors and anatomical inconsistencies. We address this limitation by moving from pixel-level to graph representations, which allow to naturally incorporate anatomical constraints by construction. To this end, we introduce HybridGNet, an encoder-decoder neural archit…
Research Institute for Signals, Systems and Computational Intelligence, sinc(i)（信号、系统与计算智能研究所）；CONICET（国家科学技术研究委员会）；Universidad Nacional del Litoral（国立滨海大学）
In this work we address the problem of landmark-based segmentation for anatomical structures. We propose HybridGNet, an encoder-decoder neural architecture which combines standard convolutions for image feature encoding, with graph convolutional neural networks to decode plausible representations of anatomical structures. We benchmark the proposed architecture considering other standard landmark and pixel-based models for anatomical segmentation in chest x-ray images, and found that HybridGNet is more robust to image occlusions. We also show that it can be used to construct landmark-based segm…
Imperial College London（伦敦帝国理工学院）；King’s College London（伦敦国王学院）
We propose a new Patch-based Iterative Network (PIN) for fast and accurate landmark localisation in 3D medical volumes. PIN utilises a Convolutional Neural Network (CNN) to learn the spatial relationship between an image patch and anatomical landmark positions. During inference, patches are repeatedly passed to the CNN until the estimated landmark position converges to the true landmark location. PIN is computationally efficient since the inference stage only selectively samples a small number of patches in an iterative fashion rather than a dense sampling at every location in the volume. Our …
CheXmask-U: Quantifying uncertainty in landmark-based anatomical segmentation for X-ray images
Laboratory of Applied Artificial Intelligence, Institute of Computer Sciences, CONICET - Universidad de Buenos Aires（应用人工智能实验室，计算机科学研究所，CONICET - 华盛顿大学布宜诺斯艾利斯分校）；Weizmann Institute of Science（科学研究所）；APOLO Biotech（APOLO生物技术）；Research Institute for Signals, Systems and Computational Intelligence, sinc(i), CONICET - Universidad Nacional del Litoral（信号、系统和计算智能研究 institute，sinc(i)，CONICET - 沿海国立大学）
Kyoto University（京都大学）；Tohoku University（东北大学）；Tokyo Institute of Technology（东京工业大学）；Nagoya University（名古屋大学）
In video-assisted thoracoscopic surgeries, successful procedures of nodule resection are highly dependent on the precise estimation of lung deformation between the inflated lung in the computed tomography (CT) images during preoperative planning and the deflated lung in the treatment views during surgery. Lungs in the pneumothorax state during surgery have a large volume change from normal lungs, making it difficult to build a mechanical model. The purpose of this study is to develop a deformation estimation method of the 3D surface of a deflated lung from a few partial observations. To estima…
IBM Research - Australia（IBM澳大利亚研究院）；EPF Laussane（洛桑联邦理工学院）
Anatomical landmark segmentation and pathology localization are important steps in automated analysis of medical images. They are particularly challenging when the anatomy or pathology is small, as in retinal images and cardiac MRI, or when the image is of low quality due to device acquisition parameters as in magnetic resonance (MR) scanners. We propose an image super-resolution method using progressive generative adversarial networks (P-GAN) that can take as input a low-resolution image and generate a high resolution image of desired scaling factor. The super resolved images can be used for …
landmarker: a Toolkit for Anatomical Landmark Localization in 2D/3D Images
IDLab；Department of Electronics and Information Systems（电子与信息系统系）；Ghent University（根特大学）；imec；Biometrics Research Group（生物识别研究组）；Department of Morphology, Imaging, Orthopedics, Rehabilitation and Nutrition（解剖学、成像、骨科、康复和营养系）
Coordinated Transformer with Position \& Sample-aware Central Loss for Anatomical Landmark Detection
Case Western Reserve University（凯斯西储大学）；The Second Affiliated Hospital of Anhui Medical University（安徽医科大学第二附属医院）；Institute of Orthopaedics, Research Center for Translational Medicine, The Second Affiliated Hospital of Anhui Medical University（安徽医科大学第二附属医院骨科研究所、转化医学研究中心）；China University of Petroleum（中国石油大学）；Guangzhou Twelfth people’s Hospital（广州市第十二人民医院）；Guangzhou Occupational Disease Prevention and Treatment Hospital（广州市职业病防治院）；Guangzhou Otolaryngology-head and Neck Surgery Hospital（广州市耳鼻咽喉头颈外科医院）；West China Hospital（华西医院）；Renmin Hospital of Wuhan University（武汉大学人民医院）
Anatomical landmarks are a crucial prerequisite for many medical imaging tasks. Usually, the set of landmarks for a given task is predefined by experts. The landmark locations for a given image are then annotated manually or via machine learning methods trained on manual annotations. In this paper, in contrast, we present a method to automatically discover and localize anatomical landmarks in medical images. Specifically, we consider landmarks that attract the visual attention of humans, which we term visually salient landmarks. We illustrate the method for fetal neurosonographic images. First…
Scientific Computing and Imaging Institute, University of Utah（犹他大学科学计算与成像研究所）；School of Computing, University of Utah（犹他大学计算学院）
Statistical shape analysis is a very useful tool in a wide range of medical and biological applications. However, it typically relies on the ability to produce a relatively small number of features that can capture the relevant variability in a population. State-of-the-art methods for obtaining such anatomical features rely on either extensive preprocessing or segmentation and/or significant tuning and post-processing. These shortcomings limit the widespread use of shape statistics. We propose that effective shape representations should provide sufficient information to align/register images. …
Landmark-free Assessment of Lower-limb Alignment with Implicit Neural Shape Functions from Knee Radiographs
Division of Informatics, Imaging and Data Sciences, The University of Manchester（曼彻斯特大学信息学、影像与数据科学部）；Research Unit of Health Sciences and Technology, University of Oulu（奥卢大学健康科学与技术研究部）；Medical Research Center Oulu, University of Oulu and Oulu University Hospital（奥卢大学与奥卢大学医院医学研究中心）；Department of Trauma and Orthopaedics, Stockport NHS Foundation Trust, Stepping Hill Hospital（斯泰平希尔医院斯托克波特NHS基金会创伤与骨科）；School of Health and Society, University of Salford（索尔福德大学健康与社会学院）；School of Biological Sciences, The University of Manchester（曼彻斯特大学生物科学学院）；Weill Cornell Medicine, Cornell University（康奈尔大学威尔康奈尔医学院）
Structure-Guided Self-Supervised Matching for One-Shot Medical Landmark Detection
Department of Computer Science（计算机科学系）；Renmin University of China（中国人民大学）；University of Science and Technology of China（中国科学技术大学）；School of Biomedical Engineering（生物医学工程学院）；School of Artificial Intelligence（人工智能学院）；Shanghai Jiaotong University（上海交通大学）；Department of Orthopedics（骨科系）；Affiliated Hospital of Guizhou Medical University（贵州医科大学附属医院）；Yale University（耶鲁大学）
Female-RHINO: A Real-Time Scanner-Integrated Framework for Automated Quantitative Uterine MRI Analysis and Structured Reporting
Radiologisches Institut, Universitätsklinikum Erlangen（埃朗根大学医院放射学研究所）；School of Biomedical Engineering and Imaging, KCL（KCL生物医学工程与成像学院）；Institute for Information Processing, Leibniz University Hannover（汉诺威莱布尼茨大学信息处理研究所）；CAIMed, L3S research institute（CAIMed，L3S研究机构）
