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arXiv 2604.27720cs.AI
对前沿视觉-语言模型进行审计以实现可信的医学视觉问答:定位失败、格式崩溃和领域适应
Why Does Grounding Hurt Medical VQA? Benchmarking, Diagnosis, and Fine-Tuning of Vision-Language Models
New York University, New York, USA(纽约大学);Tsinghua University, Beijing, China(清华大学);Columbia University, New York, USA(哥伦比亚大学);University of Michigan, Ann Arbor, USA(密歇根大学)
Xupeng Chen, Binbin Shi, Chenqian Le, Qifu Yin, Lang Lin, Haowei Ni, Ran Gong, Panfeng Li
在临床环境中部署视觉-语言模型(VLMs)需要在现实故障条件下具有可审计行为,但前沿VLMs在专门医疗输入上的故障景观尚不明确。我们审计了五种近期前沿且具有定位意识的VLMs(Gemini~2.5~Pro、GPT-5、o3、GLM-4.5V、Qwen~2.5~VL)在医学VQA上的表现,从两个与信任相关轴线进行评估。感知:所有模型对解剖学和病理学目标的定位均不佳——最佳模型仅达到0.23均值IoU和19.1% Acc@0.5,并表现出临床危险的方位混淆。流程整合:一种自我定位流程,其中同一模型先定位后回答,会降低VQA准确性,驱动因素是不准确的定位和在两步提示下的格式合规性失败(在VQA-RAD上解析失败上升至70%至99% for Gemini和GPT-5)。用地面真实注释替换预测框可恢复并提高VQA准确性,与故障位于感知模块而非分解本身一致。这些观察性发现将定位质量确定为我们在SLAKE边界框设置中的主要信任瓶颈。作为补充微调后续,对Qwen~2.5~VL进行监督微调,使用结合的Med-VQA训练数据,达到最高报告的SLAKE开放式回忆(85.5%) among comparable methods,表明VQA层面的差距可通过领域适应解决;是否这也关闭了感知/信任瓶颈还需未来工作。
英文摘要:
Vision-language models (VLMs) are increasingly applied to medical visual question answering (Med-VQA), yet whether they can \emph{localize} the evidence behind their answers---a prerequisite for clinical auditability---is poorly characterized. We separately evaluate VQA reasoning and visual grounding for four recent frontier VLMs (GPT-5.1, GPT-5.5, Gemini-2.5-Pro, Gemini-3-Flash), two domain-specific medical VLMs (Lingshu, MedGemma), and a dedicated open-vocabulary detector (Grounding DINO) on VQA-RAD and SLAKE. Two findings challenge the intuition that ``add grounding to improve VQA.'' First, \textbf{no model localizes medical targets well}: every off-the-shelf system---frontier, medical-specialized, or dedicated detector---scores mean IoU 0.05--0.24 on our SLAKE grounding split, at or barely above a trivial center-box baseline (0.10), with Acc@0.5 below 20\%. Second, and counter to the common ``localize-then-answer'' paradigm, \textbf{cropping to a bounding box degrades VQA even when the box is a perfect oracle}: on the matched subset where oracle ground-truth boxes are applied, GT-grounding \emph{lowers} closed-ended accuracy for every model (by 0.9--18.0 points versus using the full image)---consistent with the crop discarding global context the model relies on. Because the oracle box removes localization error by construction, the problem is not that perception is a recoverable bottleneck, but that grounding-by-cropping is itself the wrong interface. Finally, we show constructively that the two channels need not conflict: supervised fine-tuning of Qwen-2.5-VL-7B on answers \emph{alone} silently destroys box-evidence emission (0/418 parseable boxes), whereas mixing in a small amount of grounding supervision restores localization to 0.36 IoU---above every zero-shot model---while preserving answer accuracy.
R-GroundBench: A Diagnostic Benchmark for R-Group Groundingin Markush Molecular Editing
Westlake University(西湖大学);The University of Hong Kong(香港大学);Shanghai Innovation Institute(上海创新研究院);Zhejiang University(浙江大学);Sichuan University(四川大学);Shanghai Artificial Intelligence Laboratory(上海人工智能实验室);The Hong Kong University of Science and Technology (Guangzhou)(香港科技大学(广州));University of Illinois Urbana-Champaign(伊利诺伊大学厄巴纳-香槟分校)
DocVAL: Validated Chain-of-Thought Distillation for Grounded Document VQA
Department of Computer Science(计算机科学系);Engineering, Ohio State University, Ohio, US(工程系,俄亥俄州立大学,俄亥俄,美国);Department of Computer Science, University of Central Florida, Florida, US(计算机科学系,中央佛罗里达大学,佛罗里达,美国)
Towards Clinically Interpretable Ophthalmic VQA via Spatially-Grounded Lesion Evidence
Department of Computer Science and Engineering, Southern University of Science and Technology(南方科技大学计算机科学与工程系);The Hong Kong Polytechnic University(香港理工大学);National University of Singapore(新加坡国立大学);University of Washington(华盛顿大学);Institute of High Performance Computing, Agency for Science, Technology and Research(科技研究局高性能计算研究所)
Polish Medical Visual Question Answering: Vision-Language Models Underutilize Visual Evidence
ARAAI Poland(波兰ARAAI);NASK National Research Institute(NASK国家研究院);Poznań University of Medical Sciences(波兹南医科大学);T. Marciniak Lower Silesian Specialist Hospital(T.马尔奇尼亚克下西里西亚专科医院);Adam Mickiewicz University(亚当·密茨凯维奇大学)