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arXiv 2604.04770cs.NEq-bio.NC

平衡脊柱网络中多时间尺度振荡状态的 regime 映射

Regime Mapping of Oscillatory States in Balanced Spiking Networks with Multiple Time Scales

Tsung-Han Kuo, Tzu-Chia Tung

AI总结:

研究通过系统分析突触衰减、传导延迟和突触可塑性率如何共同塑造递归泄漏积分-微分网络中的振荡状态,揭示了参数对振荡区域和频谱显著性的影响。

摘要:

平衡脊柱网络可以根据相互作用的突触和时间尺度转换为静默、异步不规则和振荡状态,而其联合参数结构仍未完全表征。本文系统地映射了突触后衰减(τs)、传导延迟(d)和可塑性率(λp)如何共同塑造递归泄漏积分-微分网络中的振荡状态。通过结合Brian2模拟和粗略霍普夫参考边界,我们构建了能够直接可视化SIL-AI-OSC转换及相应频谱显著性景观的 regime 地图。映射结果显示,增加λp会扩展振荡区域向更短的τs和中等至长延迟方向发展,而显著性地图识别出具有最强节奏相干性的参数区域。代表性控制实验进一步将此全球景观与局部节奏形成机制联系起来,显示STDP冻结会削弱节奏相干性,而延迟抖动则在平均放电率变化极小的情况下增强它。因此,这些发现为在类似平衡网络设置中进行操作点选择、同步调节研究以及未来基于生物的脊柱网络建模提供了有用的参考。

英文摘要:

Balanced spiking networks can transition between silent, asynchronous-irregular, and oscillatory states depending on interacting synaptic and temporal time scales, while their joint parameter structure remains incompletely characterized. In this work, we systematically map how postsynaptic decay (τs), conduction delay (d), and plasticity rate (λp) jointly shape oscillatory regimes in recurrent leaky integrate-and-fire networks. By combining Brian2 simulations across the (τs, d, λp) space with a coarse Hopf-reference boundary, we construct regime maps that directly visualize SIL-AI-OSC transitions and corresponding spectral prominence landscapes. The mapped results show that increasing λp expands oscillatory regions toward shorter τs and moderate-to-long delays, while prominence maps identify parameter regions with the strongest rhythmic coherence. Representative control experiments further connect this global landscape to local rhythm-forming mechanisms, showing that STDP freezing weakens rhythmic coherence whereas delay jitter enhances it with minimal change in mean firing rate. As a result, these findings provide a useful reference for operating-point selection, synchrony modulation studies, and future biologically grounded spiking-network modeling within similar balanced-network settings.

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