射频加热增强型光声断层成像
RF heating-enhanced photoacoustic tomography
AI总结：
本研究提出了一种结合低成本射频加热器的光声断层成像技术，用于同时成像组织的光学和射频吸收，提供额外的对比度以增强诊断能力。
摘要：
光声断层成像（PAT）和热声断层成像（TAT）均利用电磁吸收产生的声学信号来非侵入性地成像深层组织。PAT通过检测光学吸收进行工作，而TAT则针对射频（RF）吸收，提供关于组织成分和结构的互补信息。将这两种模态整合到一个系统中可以提供更丰富的对比度，但仍然困难，因为RF源的费用和复杂性较高。在这里，我们展示PAT可以与低成本的射频加热器结合，并用于成像组织仿生体中的光学和射频吸收。射频加热增强型光声断层成像（HEPAT）通过温度依赖的热机械特性变化来映射射频吸收，这使得可以使用缓慢、低成本的射频子系统，并提供额外的对比度层。因此，HEPAT相对于现有光声成像系统提供了独特的、互补的对比度，扩大了特异性和诊断能力，同时开辟了研究与温度相关的组织现象的新途径。
英文摘要：
Photoacoustic tomography (PAT) and thermoacoustic tomography (TAT) both leverage acoustic signals generated by electromagnetic absorption to noninvasively image deep tissues. PAT operates by detecting optical absorption, whereas TAT targets radiofrequency (RF) absorption, providing complementary information on tissue composition and structure. Combining these modalities into a single system promises richer contrast but remains difficult due to the expense and complexity of the RF source. Here, we show that PAT can be integrated with a low-cost RF heater and used to image both optical and RF absorption in tissue phantoms. RF Heating-Enhanced Photoacoustic Tomography (HEPAT) maps RF absorption via temperature-dependent changes in thermomechanical properties, which enables the use of slow, inexpensive RF subsystems and provides an additional layer of contrast. HEPAT therefore provides distinct, complementary contrast relative to existing photoacoustic imaging systems, expanding specificity and diagnostic power while opening new avenues for studying temperature-related tissue phenomena.
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