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arXiv 2602.10367cs.AI
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LiveMedBench: 一个无污染的医疗基准测试,用于具有自动评分评估的LLM

LiveMedBench: A Contamination-Free Medical Benchmark for LLMs with Automated Rubric Evaluation

Lehigh University(莱维大学);Harvard University(哈佛大学);Imperial College London(伦敦帝国学院);Massachusetts General Hospital(麻省总医院);Harvard Medical School(哈佛医学院)

Zhiling Yan, Dingjie Song, Zhe Fang, Yisheng Ji, Xiang Li, Quanzheng Li, Lichao Sun

AI总结:

LiveMedBench通过持续更新和自动评分框架,提供无污染的医疗基准测试,验证LLM在临床推理中的性能,揭示数据污染和上下文适应性问题。

摘要:

大型语言模型(LLM)在高风险临床环境中的部署需要严格且可靠的评估。然而,现有的医疗基准测试仍然静态,存在两个关键限制:(1)数据污染,测试集意外泄露到训练语料库,导致性能估计被高估;(2)时间错位,无法捕捉医学知识的快速演变。此外,当前用于开放式临床推理的评估指标往往依赖于浅层词汇重叠(例如ROUGE)或主观LLM作为评判者评分,这两种方法都不足以验证临床正确性。为了弥补这些差距,我们引入了LiveMedBench,一个持续更新、无污染且基于评分的基准测试,每周从在线医学社区中收集现实世界的临床案例,确保严格的时间分离与模型训练数据。我们提出了一种多代理临床筛选框架,用于过滤原始数据噪声并验证临床完整性,依据循证医学原则。在评估方面,我们开发了自动评分评估框架,将医生的回应分解为细粒度、案例特定的准则,其与专家医生的对齐程度明显优于LLM作为评判者。截至目前,LiveMedBench包含2,756个现实世界案例,涵盖38个医学专业和多种语言,并配以16,702个独特的评估准则。对38个LLM的广泛评估显示,即使表现最好的模型也仅达到39.2%,且84%的模型在截止后案例上表现出性能下降,证实了普遍的数据污染风险。错误分析进一步发现,上下文应用而非事实知识是主要瓶颈,35-48%的失败源于无法将医学知识适配到患者特定约束。

英文摘要:

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination, where test sets inadvertently leak into training corpora, leading to inflated performance estimates; and (2) temporal misalignment, failing to capture the rapid evolution of medical knowledge. Furthermore, current evaluation metrics for open-ended clinical reasoning often rely on either shallow lexical overlap (e.g., ROUGE) or subjective LLM-as-a-Judge scoring, both inadequate for verifying clinical correctness. To bridge these gaps, we introduce LiveMedBench, a continuously updated, contamination-free, and rubric-based benchmark that weekly harvests real-world clinical cases from online medical communities, ensuring strict temporal separation from model training data. We propose a Multi-Agent Clinical Curation Framework that filters raw data noise and validates clinical integrity against evidence-based medical principles. For evaluation, we develop an Automated Rubric-based Evaluation Framework that decomposes physician responses into granular, case-specific criteria, achieving substantially stronger alignment with expert physicians than LLM-as-a-Judge. To date, LiveMedBench comprises 2,756 real-world cases spanning 38 medical specialties and multiple languages, paired with 16,702 unique evaluation criteria. Extensive evaluation of 38 LLMs reveals that even the best-performing model achieves only 39.2%, and 84% of models exhibit performance degradation on post-cutoff cases, confirming pervasive data contamination risks. Error analysis further identifies contextual application-not factual knowledge-as the dominant bottleneck, with 35-48% of failures stemming from the inability to tailor medical knowledge to patient-specific constraints.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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