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arXiv 2602.08576cond-mat.dis-nn
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在多发性硬化症进展中的渗透现象及阈值行为

Percolation and Threshold-like Behavior in Multiple Sclerosis Progression

Nikola Mirkov, Dušan S. Radivojević, Slobodan Maletić

AI总结:

本研究探讨多发性硬化症进展中的渗透现象及阈值行为,通过理论模型、网络分析和临床标志物,分析RRMS动态平衡是否可能突然破裂进入SPMS。

摘要:

在本研究中,我们探讨了多发性硬化症进展中的渗透假说。方法依赖于交叉参考分析,围绕一个问题:多发性硬化症(MS)中是否存在渗透/相变假说的证据,特别是RRMS动态平衡是否可以像跨越渗透阈值一样突然破裂进入SPMS?我们识别了涉及渗透/临界阈值的理论模型,评估渗透稳健性或阈值行为的网络/连接组研究,显示阈值或早期预警信号的临床标志物,以及反驳渐进/连续转变的反证。

英文摘要:

In this study we investigate the Percolation Hypothesis for Multiple Sclerosis Progression. The methodology relies on cross-reference analysis centered around a question: What is the evidence for a Percolation/phase-transition hypothesis in Multiple Sclerosis (MS), especially the idea that the RRMS dynamic balance can abruptly break akin to crossing a percolation threshold into SPMS? We identify theoretical models invoking percolation/critical thresholds, network/connectome studies assessing percolation robustness or threshold-like behavior, clinical markers showing thresholds or early-warning signals, and counter-evidence arguing for gradual/continuum transitions.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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