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arXiv 2510.05819cs.CVcs.AI

可变形图像配准用于多视角多疾病心脏磁共振图像的自监督心脏相位检测

Deformable Image Registration for Self-supervised Cardiac Phase Detection in Multi-View Multi-Disease Cardiac Magnetic Resonance Images

Department of Internal Medicine III, Heidelberg University Hospital(海德堡大学第三内科部门医院);Medical Faculty of Heidelberg University(海德堡大学医学院);DZHK (German Centre for Cardiovascular Research)(德国心血管研究中心);Division of Pediatric Cardiology, Department of Pediatrics, UT Southwestern /Children’s Health(儿童心脏病科,德克萨斯西南医学中心/儿童健康);Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School(汉诺威医学院心胸外科、移植外科和血管外科部门)

Sven Koehler, Sarah Kaye Mueller, Jonathan Kiekenap, Gerald Greil, Tarique Hussain, Samir Sarikouch, Florian André, Norbert Frey, Sandy Engelhardt

AI总结:

本文提出一种自监督深度学习方法,通过多视角多疾病心脏磁共振图像检测五个关键帧,提高了心脏相位检测的准确率,适用于SAX和4CH cine CMR。

摘要:

心血管磁共振(CMR)是评估心脏功能的金标准,但个体心脏周期复杂化了自动时间比较或亚相分析。准确的心脏关键帧检测可以解决这个问题。然而,自动方法仅从左心室体积曲线中推导出末梢收缩(ES)和末梢舒张(ED)帧,无法深入理解心肌运动。我们提出了一种自监督深度学习方法,用于在短轴(SAX)和四腔长轴(4CH) cine CMR 中检测五个关键帧。首先,从图像中密集地获得可变形配准场,并用于计算1D运动描述符,这提供了关于全局心脏收缩和放松模式的有价值见解。从这些特征曲线中,使用简单的规则确定关键帧。该方法独立评估了两种视图,使用三个公开的多中心多疾病数据集。M&Ms-2(n=360)数据集用于训练和评估,M&Ms(n=345)和ACDC(n=100)数据集用于重复性控制。此外,使用德国竞争力网络(GCN)数据集测试了对罕见先天性心脏病患者的泛化能力。我们的自监督方法在ED和ES的检测精度上比基于体积的方法提高了30% - 51%(SAX)和11% - 47%(4CH),以循环帧差(cFD)衡量。我们能够检测ED和ES,以及心脏周期中的三个额外关键帧,SAX的平均cFD低于1.31帧,LAX为1.73帧。我们的方法使无论周期或相长,都能进行时间对齐的跨和跨患者心脏动态分析。GitHub仓库:https://github.com/Cardio-AI/cmr-multi-view-phase-detection.git

英文摘要:

Cardiovascular magnetic resonance (CMR) is the gold standard for assessing cardiac function, but individual cardiac cycles complicate automatic temporal comparison or sub-phase analysis. Accurate cardiac keyframe detection can eliminate this problem. However, automatic methods solely derive end-systole (ES) and end-diastole (ED) frames from left ventricular volume curves, which do not provide a deeper insight into myocardial motion. We propose a self-supervised deep learning method detecting five keyframes in short-axis (SAX) and four-chamber long-axis (4CH) cine CMR. Initially, dense deformable registration fields are derived from the images and used to compute a 1D motion descriptor, which provides valuable insights into global cardiac contraction and relaxation patterns. From these characteristic curves, keyframes are determined using a simple set of rules. The method was independently evaluated for both views using three public, multicentre, multidisease datasets. M&Ms-2 (n=360) dataset was used for training and evaluation, and M&Ms (n=345) and ACDC (n=100) datasets for repeatability control. Furthermore, generalisability to patients with rare congenital heart defects was tested using the German Competence Network (GCN) dataset. Our self-supervised approach achieved improved detection accuracy by 30% - 51% for SAX and 11% - 47% for 4CH in ED and ES, as measured by cyclic frame difference (cFD), compared with the volume-based approach. We can detect ED and ES, as well as three additional keyframes throughout the cardiac cycle with a mean cFD below 1.31 frames for SAX and 1.73 for LAX. Our approach enables temporally aligned inter- and intra-patient analysis of cardiac dynamics, irrespective of cycle or phase lengths. GitHub repository: https://github.com/Cardio-AI/cmr-multi-view-phase-detection.git

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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