Deformable Image Registration for Self-supervised Cardiac Phase Detection in Multi-View Multi-Disease Cardiac Magnetic Resonance Images
Department of Internal Medicine III, Heidelberg University Hospital(海德堡大学第三内科部门医院);Medical Faculty of Heidelberg University(海德堡大学医学院);DZHK (German Centre for Cardiovascular Research)(德国心血管研究中心);Division of Pediatric Cardiology, Department of Pediatrics, UT Southwestern /Children’s Health(儿童心脏病科,德克萨斯西南医学中心/儿童健康);Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School(汉诺威医学院心胸外科、移植外科和血管外科部门)
Sven Koehler, Sarah Kaye Mueller, Jonathan Kiekenap, Gerald Greil, Tarique Hussain, Samir Sarikouch, Florian André, Norbert Frey, Sandy Engelhardt
本文提出一种自监督深度学习方法,通过多视角多疾病心脏磁共振图像检测五个关键帧,提高了心脏相位检测的准确率,适用于SAX和4CH cine CMR。
摘要:
心血管磁共振(CMR)是评估心脏功能的金标准,但个体心脏周期复杂化了自动时间比较或亚相分析。准确的心脏关键帧检测可以解决这个问题。然而,自动方法仅从左心室体积曲线中推导出末梢收缩(ES)和末梢舒张(ED)帧,无法深入理解心肌运动。我们提出了一种自监督深度学习方法,用于在短轴(SAX)和四腔长轴(4CH) cine CMR 中检测五个关键帧。首先,从图像中密集地获得可变形配准场,并用于计算1D运动描述符,这提供了关于全局心脏收缩和放松模式的有价值见解。从这些特征曲线中,使用简单的规则确定关键帧。该方法独立评估了两种视图,使用三个公开的多中心多疾病数据集。M&Ms-2(n=360)数据集用于训练和评估,M&Ms(n=345)和ACDC(n=100)数据集用于重复性控制。此外,使用德国竞争力网络(GCN)数据集测试了对罕见先天性心脏病患者的泛化能力。我们的自监督方法在ED和ES的检测精度上比基于体积的方法提高了30% - 51%(SAX)和11% - 47%(4CH),以循环帧差(cFD)衡量。我们能够检测ED和ES,以及心脏周期中的三个额外关键帧,SAX的平均cFD低于1.31帧,LAX为1.73帧。我们的方法使无论周期或相长,都能进行时间对齐的跨和跨患者心脏动态分析。GitHub仓库:https://github.com/Cardio-AI/cmr-multi-view-phase-detection.git
英文摘要:
Cardiovascular magnetic resonance (CMR) is the gold standard for assessing cardiac function, but individual cardiac cycles complicate automatic temporal comparison or sub-phase analysis. Accurate cardiac keyframe detection can eliminate this problem. However, automatic methods solely derive end-systole (ES) and end-diastole (ED) frames from left ventricular volume curves, which do not provide a deeper insight into myocardial motion. We propose a self-supervised deep learning method detecting five keyframes in short-axis (SAX) and four-chamber long-axis (4CH) cine CMR. Initially, dense deformable registration fields are derived from the images and used to compute a 1D motion descriptor, which provides valuable insights into global cardiac contraction and relaxation patterns. From these characteristic curves, keyframes are determined using a simple set of rules. The method was independently evaluated for both views using three public, multicentre, multidisease datasets. M&Ms-2 (n=360) dataset was used for training and evaluation, and M&Ms (n=345) and ACDC (n=100) datasets for repeatability control. Furthermore, generalisability to patients with rare congenital heart defects was tested using the German Competence Network (GCN) dataset. Our self-supervised approach achieved improved detection accuracy by 30% - 51% for SAX and 11% - 47% for 4CH in ED and ES, as measured by cyclic frame difference (cFD), compared with the volume-based approach. We can detect ED and ES, as well as three additional keyframes throughout the cardiac cycle with a mean cFD below 1.31 frames for SAX and 1.73 for LAX. Our approach enables temporally aligned inter- and intra-patient analysis of cardiac dynamics, irrespective of cycle or phase lengths. GitHub repository: https://github.com/Cardio-AI/cmr-multi-view-phase-detection.git
Stroke Extraction of Chinese Character Based on Deep Structure Deformable Image Registration
Institute of Automation, Chinese Academy of Sciences(中国科学院自动化研究所);School of Artificial Intelligence, University of Chinese Academy of Sciences(中国科学院大学人工智能学院)
Fraunhofer MEVIS(弗劳恩霍夫医学图像计算研究所);Radboud UMC(拉德堡德大学医学中心);University of Lübeck(吕贝克大学)
While deep learning has achieved significant advances in accuracy for medical image segmentation, its benefits for deformable image registration have so far remained limited to reduced computation times. Previous work has either focused on replacing the iterative optimization of distance and smoothness terms with CNN-layers or using supervised approaches driven by labels. Our method is the first to combine the complementary strengths of global semantic information (represented by segmentation labels) and local distance metrics that help align surrounding structures. We demonstrate significant …
Surrogate Supervision for Robust and Generalizable Deformable Image Registration
Department of Electrical and Computer Engineering, Vanderbilt University(维斯尼尔大学电气与计算机工程系);Department of Radiology and Radiological Science, Johns Hopkins Medical School(约翰霍普金斯医学学校放射学与放射科学系);Image Analysis and Communications Laboratory in the Department of Electrical and Computer Engineering, Johns Hopkins University(约翰霍普金斯大学电气与计算机工程系图像分析与通信实验室);Center for Cognitive Medicine, Department of Psychiatry and Behavioral Science, Vanderbilt University Medical Center(维斯尼尔大学医学中心认知医学中心);University of Pittsburgh, School of Medicine(匹兹堡大学医学院)
Image Sciences Institute, University Medical Center Utrecht and Utrecht University(乌得勒支大学医学中心与乌得勒支大学影像科学研究所);Division of Image Processing of the Leiden University Medical Center(莱顿大学医学中心图像处理部)
Image registration, the process of aligning two or more images, is the core technique of many (semi-)automatic medical image analysis tasks. Recent studies have shown that deep learning methods, notably convolutional neural networks (ConvNets), can be used for image registration. Thus far training of ConvNets for registration was supervised using predefined example registrations. However, obtaining example registrations is not trivial. To circumvent the need for predefined examples, and thereby to increase convenience of training ConvNets for image registration, we propose the Deep Learning Im…
Non-iterative Coarse-to-fine Transformer Networks for Joint Affine and Deformable Image Registration
School of Computer Science, The University of Sydney(悉尼大学计算机科学学院);Institute of Translational Medicine, Shanghai Jiao Tong University(上海交通大学转化医学研究院);Royal Prince Alfred Hospital(皇家阿尔弗雷德王子医院);Med-X Research Institute, Shanghai Jiao Tong University(上海交通大学Med-X研究院)
Image Sciences Institute, University Medical Center Utrecht(乌得勒支大学医学中心图像科学研究所);Division of Image Processing, Leiden University Medical Center(莱顿大学医学中心图像处理部)
In this work we propose a deep learning network for deformable image registration (DIRNet). The DIRNet consists of a convolutional neural network (ConvNet) regressor, a spatial transformer, and a resampler. The ConvNet analyzes a pair of fixed and moving images and outputs parameters for the spatial transformer, which generates the displacement vector field that enables the resampler to warp the moving image to the fixed image. The DIRNet is trained end-to-end by unsupervised optimization of a similarity metric between input image pairs. A trained DIRNet can be applied to perform registration …
University College London(伦敦大学学院);Massachusetts General Hospital(马萨诸塞总医院);Harvard Medical School(哈佛医学院);Massachusetts Institute of Technology(麻省理工学院)
Landmark correspondences are a widely used type of gold standard in image registration. However, the manual placement of corresponding points is subject to high inter-user variability in the chosen annotated locations and in the interpretation of visual ambiguities. In this paper, we introduce a principled strategy for the construction of a gold standard in deformable registration. Our framework: (i) iteratively suggests the most informative location to annotate next, taking into account its redundancy with previous annotations; (ii) extends traditional pointwise annotations by accounting for …
Deformable image registration, i.e., the task of aligning multiple images into one coordinate system by non-linear transformation, serves as an essential preprocessing step for neuroimaging data. Recent research on deformable image registration is mainly focused on improving the registration accuracy using multi-stage alignment methods, where the source image is repeatedly deformed in stages by a same neural network until it is well-aligned with the target image. Conventional methods for multi-stage registration can often blur the source image as the pixel/voxel values are repeatedly interpola…
University of North Carolina(北卡罗来纳大学);Shanghai Jiao Tong University(上海交通大学)
Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In this paper, we propose an infant-dedicated deep registration network that uses the auto-context strategy to gradually refine the deformation fields to obtain highly accurate correspondences. Instead of training multiple registration networks, our method estimates the deformation fields by invoking a single network multiple times for iterative deformation refine…
University of Bern(伯尔尼大学);CentraleSupélec(中央理工-高等电力学院);Université Paris-Saclay(巴黎-萨克雷大学);Groupe Hospitalier Cochin-Hôtel Dieu(科钦-主宫医院集团);Université Paris Descartes(巴黎笛卡尔大学);TheraPanacea
Image registration and in particular deformable registration methods are pillars of medical imaging. Inspired by the recent advances in deep learning, we propose in this paper, a novel convolutional neural network architecture that couples linear and deformable registration within a unified architecture endowed with near real-time performance. Our framework is modular with respect to the global transformation component, as well as with respect to the similarity function while it guarantees smooth displacement fields. We evaluate the performance of our network on the challenging problem of MRI …
University of Cambridge(剑桥大学);Cancer Research UK Cambridge Centre(英国癌症研究中心剑桥中心);Medical University Vienna(维也纳医科大学);Cambridge University Hospitals National Health Service (NHS) Foundation Trust(剑桥大学医院国民保健服务基金会信托);Eindhoven University of Technology(埃因霍温理工大学);Leiden University(莱顿大学);University College London(伦敦大学学院);Cancer Research UK Cambridge Institute(英国癌症研究中心剑桥研究所)
This study investigates the use of the unsupervised deep learning framework VoxelMorph for deformable registration of longitudinal abdominopelvic CT images acquired in patients with bone metastases from breast cancer. The CT images were refined prior to registration by automatically removing the CT table and all other extra-corporeal components. To improve the learning capabilities of VoxelMorph when only a limited amount of training data is available, a novel incremental training strategy is proposed based on simulated deformations of consecutive CT images. In a 4-fold cross-validation scheme…
Domain-Shift Immunity in Deep Deformable Registration via Local Feature Representations
Kahlert School of Computing(卡尔伯特计算学校);Scientific Computing and Imaging Institute(科学计算与成像研究所);University of Utah(犹他大学);Department of Biomedical Engineering(生物医学工程系)
Fraunhofer Institute for Medical Image Computing (MEVIS)(弗劳恩霍夫医学图像计算研究所(MEVIS));Universität zu Lübeck(吕贝克大学)
We present a highly parallel method for accurate and efficient variational deformable 3D image registration on a consumer-grade graphics processing unit (GPU). We build on recent matrix-free variational approaches and specialize the concepts to the massively-parallel manycore architecture provided by the GPU. Compared to a parallel and optimized CPU implementation, this allows us to achieve an average speedup of 32.53 on 986 real-world CT thorax-abdomen follow-up scans. At a resolution of approximately $256^3$ voxels, the average runtime is 1.99 seconds for the full registration. On the public…
Tsinghua University(清华大学);Brigham and Women’s Hospital(布莱根妇女医院);Harvard Medical School(哈佛医学院)
Deformable image registration (DIR) is essential for many image-guided therapies. Recently, deep learning approaches have gained substantial popularity and success in DIR. Most deep learning approaches use the so-called mono-stream "high-to-low, low-to-high" network structure, and can achieve satisfactory overall registration results. However, accurate alignments for some severely deformed local regions, which are crucial for pinpointing surgical targets, are often overlooked. Consequently, these approaches are not sensitive to some hard-to-align regions, e.g., intra-patient registration of de…
University of Kansas(堪萨斯大学);Rochester Institute of Technology(罗切斯特理工学院)
Patient-specific left ventricle (LV) myocardial models have the potential to be used in a variety of clinical scenarios for improved diagnosis and treatment plans. Cine cardiac magnetic resonance (MR) imaging provides high resolution images to reconstruct patient-specific geometric models of the LV myocardium. With the advent of deep learning, accurate segmentation of cardiac chambers from cine cardiac MR images and unsupervised learning for image registration for cardiac motion estimation on a large number of image datasets is attainable. Here, we propose a deep leaning-based framework for th…
AutoFuse: Automatic Fusion Networks for Deformable Medical Image Registration
School of Computer Science, The University of Sydney(悉尼大学计算机科学学院);Institute of Translational Medicine, Shanghai Jiao Tong University(上海交通大学转化医学研究院);Royal Prince Alfred Hospital(皇家阿尔弗雷德王子医院)
Robarts Research Institute(罗巴茨研究所);Western University(韦仕敦大学)
Optimization techniques have been widely used in deformable registration, allowing for the incorporation of similarity metrics with regularization mechanisms. These regularization mechanisms are designed to mitigate the effects of trivial solutions to ill-posed registration problems and to otherwise ensure the resulting deformation fields are well-behaved. This paper introduces a novel deformable registration algorithm, RANCOR, which uses iterative convexification to address deformable registration problems under total-variation regularization. Initial comparative results against four state-of…
University of Edinburgh(爱丁堡大学);Imperial College London(帝国理工学院);University of Essex(埃塞克斯大学)
Magnetic Resonance Imaging (MRI) typically recruits multiple sequences (defined here as "modalities"). As each modality is designed to offer different anatomical and functional clinical information, there are evident disparities in the imaging content across modalities. Inter- and intra-modality affine and non-rigid image registration is an essential medical image analysis process in clinical imaging, as for example before imaging biomarkers need to be derived and clinically evaluated across different MRI modalities, time phases and slices. Although commonly needed in real clinical scenarios, …
Johns Hopkins Medical Institutes(约翰斯·霍普金斯医学研究所);Johns Hopkins University(约翰斯·霍普金斯大学);NVIDIA Corporation(英伟达公司)
Transformers have recently shown promise for medical image applications, leading to an increasing interest in developing such models for medical image registration. Recent advancements in designing registration Transformers have focused on using cross-attention (CA) to enable a more precise understanding of spatial correspondences between moving and fixed images. Here, we propose a novel CA mechanism that computes windowed attention using deformable windows. In contrast to existing CA mechanisms that require intensive computational complexity by either computing CA globally or locally with a f…
The Hong Kong University of Science and Technology(香港科技大学)
Registration of pre-operative and post-recurrence brain images is often needed to evaluate the effectiveness of brain gliomas treatment. While recent deep learning-based deformable registration methods have achieved remarkable success with healthy brain images, most of them would be unable to accurately align images with pathologies due to the absent correspondences in the reference image. In this paper, we propose a deep learning-based deformable registration method that jointly estimates regions with absent correspondence and bidirectional deformation fields. A forward-backward consistency c…
The Hong Kong University of Science and Technology(香港科技大学)
Recent deep learning-based methods have shown promising results and runtime advantages in deformable image registration. However, analyzing the effects of hyperparameters and searching for optimal regularization parameters prove to be too prohibitive in deep learning-based methods. This is because it involves training a substantial number of separate models with distinct hyperparameter values. In this paper, we propose a conditional image registration method and a new self-supervised learning paradigm for deep deformable image registration. By learning the conditional features that are correla…
University of Lübeck(吕贝克大学);Fraunhofer MEVIS(弗劳恩霍夫医学影像计算研究所)
Low-rank and sparse decompositions and robust PCA (RPCA) are highly successful techniques in image processing and have recently found use in groupwise image registration. In this paper, we investigate the drawbacks of the most common RPCA-dissimi\-larity metric in image registration and derive an improved version. In particular, this new metric models low-rank requirements through explicit constraints instead of penalties and thus avoids the pitfalls of the established metric. Equipped with total variation regularization, we present a theoretically justified multilevel scheme based on first-or…
Deformable image registration is a fundamental task in medical image analysis, aiming to establish a dense and non-linear correspondence between a pair of images. Previous deep-learning studies usually employ supervised neural networks to directly learn the spatial transformation from one image to another, requiring task-specific ground-truth registration for model training. Due to the difficulty in collecting precise ground-truth registration, implementation of these supervised methods is practically challenging. Although several unsupervised networks have been recently developed, these metho…
We present INSPIRE, a top-performing general-purpose method for deformable image registration. INSPIRE brings distance measures which combine intensity and spatial information into an elastic B-splines-based transformation model and incorporates an inverse inconsistency penalization supporting symmetric registration performance. We introduce several theoretical and algorithmic solutions which provide high computational efficiency and thereby applicability of the proposed framework in a wide range of real scenarios. We show that INSPIRE delivers highly accurate, as well as stable and robust reg…
Korea Advanced Institute of Science and Technology (KAIST)(韩国科学技术院)
Deformable image registration is one of the fundamental tasks in medical imaging. Classical registration algorithms usually require a high computational cost for iterative optimizations. Although deep-learning-based methods have been developed for fast image registration, it is still challenging to obtain realistic continuous deformations from a moving image to a fixed image with less topological folding problem. To address this, here we present a novel diffusion-model-based image registration method, called DiffuseMorph. DiffuseMorph not only generates synthetic deformed images through revers…
Deformable templates are essential to large-scale medical image registration, segmentation, and population analysis. Current conventional and deep network-based methods for template construction use only regularized registration objectives and often yield templates with blurry and/or anatomically implausible appearance, confounding downstream biomedical interpretation. We reformulate deformable registration and conditional template estimation as an adversarial game wherein we encourage realism in the moved templates with a generative adversarial registration framework conditioned on flexible i…
Korea Advanced Institute of Science and Technology(韩国科学技术院);University of Ulsan College of Medicine(蔚山大学医学院);Asan Medical Center(峨山医学中心)
Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to its excellent performance in spite of ultra-fast computational time compared to the classical approaches. In this paper, we present a novel unsupervised medical image registration method that trains deep neural network for deformable registration of 3D volumes using a cycle-consistency. Thanks to the cycle consistency, the proposed deep neural networks can t…
Huazhong University of Science and Technology(华中科技大学);College of Life Science and Technology, Huazhong University of Science and Technology(华中科技大学生命科学与技术学院)
Deformable medical image registration plays an important role in clinical diagnosis and treatment. Recently, the deep learning (DL) based image registration methods have been widely investigated and showed excellent performance in computational speed. However, these methods cannot provide enough registration accuracy because of insufficient ability in representing both the global and local features of the moving and fixed images. To address this issue, this paper has proposed the transformer based image registration method. This method uses the distinctive transformer to extract the global and…
New York University(纽约大学);Hyperfine Research(Hyperfine研究公司);Yale University(耶鲁大学)
Establishing voxelwise semantic correspondence across distinct imaging modalities is a foundational yet formidable computer vision task. Current multi-modality registration techniques maximize hand-crafted inter-domain similarity functions, are limited in modeling nonlinear intensity-relationships and deformations, and may require significant re-engineering or underperform on new tasks, datasets, and domain pairs. This work presents ContraReg, an unsupervised contrastive representation learning approach to multi-modality deformable registration. By projecting learned multi-scale local patch fe…
Johns Hopkins University(约翰斯·霍普金斯大学);National Institute on Aging(国家老龄化研究所);National Institute of Health(美国国立卫生研究院)
The majority of deep learning (DL) based deformable image registration methods use convolutional neural networks (CNNs) to estimate displacement fields from pairs of moving and fixed images. This, however, requires the convolutional kernels in the CNN to not only extract intensity features from the inputs but also understand image coordinate systems. We argue that the latter task is challenging for traditional CNNs, limiting their performance in registration tasks. To tackle this problem, we first introduce Coordinate Translator, a differentiable module that identifies matched features between…
Johns Hopkins University(约翰斯·霍普金斯大学);PAII Inc.(PAII公司);Ping An Technology(平安科技);The First Affiliated Hospital Zhejiang University(浙江大学医学院附属第一医院)
In this work, we introduce a fast and accurate method for unsupervised 3D medical image registration. This work is built on top of a recent algorithm SAM, which is capable of computing dense anatomical/semantic correspondences between two images at the pixel level. Our method is named SAME, which breaks down image registration into three steps: affine transformation, coarse deformation, and deep deformable registration. Using SAM embeddings, we enhance these steps by finding more coherent correspondences, and providing features and a loss function with better semantic guidance. We collect a mu…
Research institute for signals, systems and computational intelligence, sinc(i), FICH-UNL/CONICET(信号、系统与计算智能研究所 sinc(i),FICH-UNL/CONICET);University of Oxford(牛津大学);TheraPanacea;CentraleSupelec(中央理工-高等电力学院);Universite Paris-Saclay(巴黎-萨克雷大学)
Deformable registration has been one of the pillars of biomedical image computing. Conventional approaches refer to the definition of a similarity criterion that, once endowed with a deformation model and a smoothness constraint, determines the optimal transformation to align two given images. The definition of this metric function is among the most critical aspects of the registration process. We argue that incorporating semantic information (in the form of anatomical segmentation maps) into the registration process will further improve the accuracy of the results. In this paper, we propose a…
Deformable image registration is able to achieve fast and accurate alignment between a pair of images and thus plays an important role in many medical image studies. The current deep learning (DL)-based image registration approaches directly learn the spatial transformation from one image to another by leveraging a convolutional neural network, requiring ground truth or similarity metric. Nevertheless, these methods only use a global similarity energy function to evaluate the similarity of a pair of images, which ignores the similarity of regions of interest (ROIs) within images. Moreover, DL-…
Dalian University of Technology(大连理工大学);Guilin University of Electronic Technology(桂林电子科技大学);Children’s Hospital of Philadelphia(费城儿童医院);University of Pennsylvania(宾夕法尼亚大学)
Conventional deformable registration methods aim at solving an optimization model carefully designed on image pairs and their computational costs are exceptionally high. In contrast, recent deep learning based approaches can provide fast deformation estimation. These heuristic network architectures are fully data-driven and thus lack explicit geometric constraints, e.g., topology-preserving, which are indispensable to generate plausible deformations. We design a new deep learning based framework to optimize a diffeomorphic model via multi-scale propagation in order to integrate advantages and …
Technion – Israel Institute of Technology(以色列理工学院)
Unsupervised deep-learning (DL) models were recently proposed for deformable image registration tasks. In such models, a neural-network is trained to predict the best deformation field by minimizing some dissimilarity function between the moving and the target images. After training on a dataset without reference deformation fields available, such a model can be used to rapidly predict the deformation field between newly seen moving and target images. Currently, the training process effectively provides a point-estimate of the network weights rather than characterizing their entire posterior d…
Deformable image registration (DIR), aiming to find spatial correspondence between images, is one of the most critical problems in the domain of medical image analysis. In this paper, we present a novel, generic, and accurate diffeomorphic image registration framework that utilizes neural ordinary differential equations (NODEs). We model each voxel as a moving particle and consider the set of all voxels in a 3D image as a high-dimensional dynamical system whose trajectory determines the targeted deformation field. Our method leverages deep neural networks for their expressive power in modeling…
Unsupervised Deformable Image Registration with Local-Global Attention and Image Decomposition
Institute of Medical Technology, Peking University Health Science Center(北京大学医学部医学技术研究所);National Institute of Health Data Science, Peking University(北京大学国家健康数据科学研究院);Department of Radiology, Peking University Third Hospital(北京大学第三医院放射科);Department of Pediatrics, Peking University First Hospital(北京大学第一医院儿科);Pediatric Epilepsy Center, Peking University First Hospital(北京大学第一医院儿童癫痫中心);School of Biological Science and Medical Engineering, Southeast University(东南大学生物科学与医学工程学院);Institute for Artificial Intelligence, Peking University(北京大学人工智能研究院)
Vector Field Attention for Deformable Image Registration
Johns Hopkins University(约翰斯·霍普金斯大学);Johns Hopkins School of Medicine(约翰斯·霍普金斯医学院);National Institute on Aging(美国国家老龄化研究所);National Institute of Health(美国国立卫生研究院)
Deformable surface tracking from monocular images is well-known to be under-constrained. Occlusions often make the task even more challenging, and can result in failure if the surface is not sufficiently textured. In this work, we explicitly address the problem of 3D reconstruction of poorly textured, occluded surfaces, proposing a framework based on a template-matching approach that scales dense robust features by a relevancy score. Our approach is extensively compared to current methods employing both local feature matching and dense template alignment. We test on standard datasets as well a…
Point cloud-based registration and image fusion between cardiac SPECT MPI and CTA
Xi’an University of Posts and Telecommunications(西安邮电大学);Nanjing Medical University(南京医科大学);The First Affiliated Hospital of Nanjing Medical University(南京医科大学第一附属医院);The First Affiliated Hospital of Xi’an Jiaotong University(西安交通大学第一附属医院);Kennesaw State University(肯尼索州立大学);Michigan Technological University(密歇根理工大学)
Evaluation of Deformable Image Registration under Alignment-Regularity Trade-off
Technical University of Munich (TUM)(慕尼黑技术大学);TUM University Hospital, Munich, Germany(慕尼黑技术大学医院);Munich Center for Machine Learning (MCML)(慕尼黑机器学习中心);Department of Computing, Imperial College London(伦敦帝国理工学院计算机系)