从隐喻到机制：LLMs如何解码中医符号语言以实现现代临床相关性
From Metaphor to Mechanism: How LLMs Decode Traditional Chinese Medicine Symbolic Language for Modern Clinical Relevance
AI总结：
本文提出一种结合多智能体与思维链（CoT）的框架，利用TCM Expert、WM Expert与Coordinator Agent协同推理，将中医隐喻术语映射为西医病理生理学概念，以支持临床决策与跨医学体系研究。
摘要：
中医（TCM）中充满了隐喻表达，通过文化丰富且通常抽象的术语传达复杂的疾病机制和整体健康概念。将这些隐喻桥接到以解剖学为导向的西医（WM）概念，对自动语言处理和现实世界的临床实践都构成了重大挑战。为了解决这一差距，我们提出了一种新颖的多智能体和思维链（CoT）框架，旨在准确解释TCM隐喻并将其映射到WM病理生理学。具体而言，我们的方法将领域专业化智能体（TCM Expert、WM Expert）与Coordinator Agent相结合，利用逐步的思维链提示来确保透明的推理和冲突解决。我们详细介绍了构建富含隐喻的TCM数据集的方法论，讨论了有效整合多智能体协作和CoT推理的策略，并阐明了指导跨不同医学范式隐喻解释的理论基础。我们提出了一个全面的系统设计，并强调了我们方法的潜在益处和局限性，同时为未来的实验验证留出了占位符。我们的工作旨在支持临床决策、跨系统教育举措和综合医疗保健研究，最终为调和TCM的符号语言与西医的机制焦点提供一个稳健的支架。
英文摘要：
Metaphorical expressions are abundant in Traditional Chinese Medicine (TCM), conveying complex disease mechanisms and holistic health concepts through culturally rich and often abstract terminology. Bridging these metaphors to anatomically driven Western medical (WM) concepts poses significant challenges for both automated language processing and real-world clinical practice. To address this gap, we propose a novel multi-agent and chain-of-thought (CoT) framework designed to interpret TCM metaphors accurately and map them to WM pathophysiology. Specifically, our approach combines domain-specialized agents (TCM Expert, WM Expert) with a Coordinator Agent, leveraging stepwise chain-of-thought prompts to ensure transparent reasoning and conflict resolution. We detail a methodology for building a metaphor-rich TCM dataset, discuss strategies for effectively integrating multi-agent collaboration and CoT reasoning, and articulate the theoretical underpinnings that guide metaphor interpretation across distinct medical paradigms. We present a comprehensive system design and highlight both the potential benefits and limitations of our approach, while leaving placeholders for future experimental validation. Our work aims to support clinical decision-making, cross-system educational initiatives, and integrated healthcare research, ultimately offering a robust scaffold for reconciling TCM's symbolic language with the mechanistic focus of Western medicine.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
