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暗脑能量:迈向自发慢振荡的整合模型

Dark Brain Energy: Toward an Integrative Model of Spontaneous Slow Oscillations

ZhuQing Gong, XiNian Zuo

AI总结:

本文综述了过去15年基于多频段频率分析的自发慢振荡研究,并提出一个整合多频段SSOs功能的层级组织模型,以弥合理论空白并指导未来研究。

摘要:

神经振荡在空间和时间维度上以不同频率促进人脑的功能运作。这些振荡具有一种受脑解剖结构支配的通用频率架构,确保频率特异性在不同测量技术之间保持不变。早期的磁共振成像(MRI)方法将功能磁共振成像(fMRI)研究限制在单一频率范围内,从而忽略了血氧水平依赖振荡中固有的频率特性。随着MRI技术的进步,通过多频段频率分析(MBFA)解码复杂的脑活动已成为可能。在过去十年中,MBFA在fMRI研究中的应用迅速增长,揭示了自发慢振荡(SSOs)的频率依赖性特征,这些振荡被认为是大脑中暗能量的基础。关于不同频段中SSOs的性质和功能,目前仍缺乏确切的见解和假说。我们综述了过去15年中的SSO MBFA研究,以描绘SSOs的属性并阐明其相关功能。我们进一步提出了一个模型,通过整合多频段SSOs的功能来阐明其层级组织,旨在弥合理论空白并指导未来的MBFA研究工作。

英文摘要:

Neural oscillations facilitate the functioning of the human brain in spatial and temporal dimensions at various frequencies. These oscillations feature a universal frequency architecture that is governed by brain anatomy, ensuring frequency specificity remains invariant across different measurement techniques. Initial magnetic resonance imaging (MRI) methodology constrained functional MRI (fMRI) investigations to a singular frequency range, thereby neglecting the frequency characteristics inherent in blood oxygen level-dependent oscillations. With advancements in MRI technology, it has become feasible to decode intricate brain activities via multi-band frequency analysis (MBFA). During the past decade, the utilization of MBFA in fMRI studies has surged, unveiling frequency-dependent characteristics of spontaneous slow oscillations (SSOs) believed to base dark energy in the brain. There remains a dearth of conclusive insights and hypotheses pertaining to the properties and functionalities of SSOs in distinct bands. We surveyed the SSO MBFA studies during the past 15 years to delineate the attributes of SSOs and enlighten their correlated functions. We further proposed a model to elucidate the hierarchical organization of multi-band SSOs by integrating their function, aimed at bridging theoretical gaps and guiding future MBFA research endeavors.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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