Diffusion models demonstrate state-of-the-art performance on image generation, and are gaining traction for sparse medical image reconstruction tasks. However, compared to classical reconstruction algorithms relying on simple analytical priors, diffusion models have the dangerous property of producing realistic looking results \emph{even when incorrect}, particularly with few observations. We investigate the utility of diffusion models as priors for image reconstruction by varying the number of observations and comparing their performance to classical priors (sparse and Tikhonov regularization) using pixel-based, structural, and downstream metrics. We make comparisons on low-dose chest wall computed tomography (CT) for fat mass quantification. First, we find that classical priors are superior to diffusion priors when the number of projections is ``sufficient''. Second, we find that diffusion priors can capture a large amount of detail with very few observations, significantly outperforming classical priors. However, they fall short of capturing all details, even with many observations. Finally, we find that the performance of diffusion priors plateau after extremely few ($\approx$10-15) projections. Ultimately, our work highlights potential issues with diffusion-based sparse reconstruction and underscores the importance of further investigation, particularly in high-stakes clinical settings.
GE Global Research（GE全球研究中心）；Tel Aviv University（特拉维夫大学）；GE Healthcare（GE医疗）
Recent sparse MRI reconstruction models have used Deep Neural Networks (DNNs) to reconstruct relatively high-quality images from highly undersampled k-space data, enabling much faster MRI scanning. However, these techniques sometimes struggle to reconstruct sharp images that preserve fine detail while maintaining a natural appearance. In this work, we enhance the image quality by using a Conditional Wasserstein Generative Adversarial Network combined with a novel Adaptive Gradient Balancing technique that stabilizes the training and minimizes the degree of artifacts, while maintaining a high-q…
The University of Hong Kong（香港大学）；Tencent Games（腾讯游戏）；Texas A&M University（得克萨斯农工大学）
We introduce SparseNeuS, a novel neural rendering based method for the task of surface reconstruction from multi-view images. This task becomes more difficult when only sparse images are provided as input, a scenario where existing neural reconstruction approaches usually produce incomplete or distorted results. Moreover, their inability of generalizing to unseen new scenes impedes their application in practice. Contrarily, SparseNeuS can generalize to new scenes and work well with sparse images (as few as 2 or 3). SparseNeuS adopts signed distance function (SDF) as the surface representation,…
LUCID: Learned Undersampling-Adaptive Consistency-Guided Inference with Deterministic Flow Matching for Sparse-View CT Reconstruction
School of Mathematical Sciences, Capital Normal University（首都师范大学数学科学学院）；National Center for Applied Mathematics Beijing, Capital Normal University（首都师范大学北京国家应用数学中心）；Academy for Multidisciplinary Studies, Capital Normal University（首都师范大学交叉科学研究院）
Physics-Guided Null-Space Diffusion with Sparse Masking for Corrective Sparse-View CT Reconstruction
School of Information Engineering, Nanchang University, Nanchang, China（信息工程学院，南昌大学，南昌，中国）；School of Mathematics and Computer Sciences, Nanchang University, Nanchang, China（数学与计算机科学学院，南昌大学，南昌，中国）
We propose SparseFusion, a sparse view 3D reconstruction approach that unifies recent advances in neural rendering and probabilistic image generation. Existing approaches typically build on neural rendering with re-projected features but fail to generate unseen regions or handle uncertainty under large viewpoint changes. Alternate methods treat this as a (probabilistic) 2D synthesis task, and while they can generate plausible 2D images, they do not infer a consistent underlying 3D. However, we find that this trade-off between 3D consistency and probabilistic image generation does not need to e…
In this paper, the Primal-Dual UNet for sparse view CT reconstruction is modified to be applicable to cone beam projections and perform reconstructions of entire volumes instead of slices. Experiments show that the PSNR of the proposed method is increased by 10dB compared to the direct FDK reconstruction and almost 3dB compared to the modified original Primal-Dual Network when using only 23 projections. The presented network is not optimized wrt. memory consumption or hyperparameters but merely serves as a proof of concept and is limited to low resolution projections and volumes.
Recently, a number of approaches to low-dose computed tomography (CT) have been developed and deployed in commercialized CT scanners. Tube current reduction is perhaps the most actively explored technology with advanced image reconstruction algorithms. Sparse data sampling is another viable option to the low-dose CT, and sparse-view CT has been particularly of interest among the researchers in CT community. Since analytic image reconstruction algorithms would lead to severe image artifacts, various iterative algorithms have been developed for reconstructing images from sparsely view-sampled pr…
Traditional dictionary learning based CT reconstruction methods are patch-based and the features learned with these methods often contain shifted versions of the same features. To deal with these problems, the convolutional sparse coding (CSC) has been proposed and introduced into various applications. In this paper, inspired by the successful applications of CSC in the field of signal processing, we propose a novel sparse-view CT reconstruction method based on CSC with gradient regularization on feature maps. By directly working on whole image, which need not to divide the image into overlapp…
Graduate School of Informatics, Kyoto University（京都大学信息学院研究生院）
This paper introduces an elasticity reconstruction method based on local displacement observations of elastic bodies. Sparse reconstruction theory is applied to formulate the underdetermined inverse problems of elasticity reconstruction including unobserved areas. An online local clustering scheme called a superelement is proposed to reduce the number of dimensions of the optimization parameters. Alternating the optimization of element boundaries and elasticity parameters enables the elasticity distribution to be estimated with a higher spatial resolution. The simulation experiments show that …
X-ray Computed Tomography (CT) imaging has been widely used in clinical diagnosis, non-destructive examination, and public safety inspection. Sparse-view (sparse view) CT has great potential in radiation dose reduction and scan acceleration. However, sparse view CT data is insufficient and traditional reconstruction results in severe streaking artifacts. In this work, based on deep learning, we compared image reconstruction performance for sparse view CT reconstruction with projection domain network, image domain network, and comprehensive network combining projection and image domains. Our st…
Sparse-view computed tomography (CT) can be used to reduce radiation dose greatly but is suffers from severe image artifacts. Recently, the deep learning based method for sparse-view CT reconstruction has attracted a major attention. However, neural networks often have a limited ability to remove the artifacts when they only work in the image domain. Deep learning-based sinogram processing can achieve a better anti-artifact performance, but it inevitably requires feature maps of the whole image in a video memory, which makes handling large-scale or three-dimensional (3D) images rather challeng…
The sparse-views x-ray computed tomography (CT) is essential for medical diagnosis and industrial nondestructive testing. However, in particular, the reconstructed image usually suffers from complex artifacts and noise, when the sampling is insufficient. In order to deal such issue, a full-automatic reconstruction (FAR) net is proposed for sparse-views CT reconstruction via deep learning technique. Different with the usual network in deep learning reconstruction, the proposed neural network is an End-to-End network by which the image is predicted directly from projection data. The main challen…
Dynamic Contrast-enhanced magnetic resonance imaging (DCE-MRI) is a tissue perfusion imaging technique. Some versatile free-breathing DCE-MRI techniques combining compressed sensing (CS) and parallel imaging with golden-angle radial sampling have been developed to improve motion robustness with high spatial and temporal resolution. These methods have demonstrated good diagnostic performance in clinical setting, but the reconstruction quality will degrade at high acceleration rates and overall reconstruction time remains long. In this paper, we proposed a new parallel CS reconstruction model fo…
Xiamen University of Technology（厦门理工学院）；Xiamen University（厦门大学）；China Mobile Group（中国移动集团）；University of Gothenburg（哥德堡大学）
The non-uniform sampling is a powerful approach to enable fast acquisition but requires sophisticated reconstruction algorithms. Faithful reconstruction from partial sampled exponentials is highly expected in general signal processing and many applications. Deep learning has shown astonishing potential in this field but many existing problems, such as lack of robustness and explainability, greatly limit its applications. In this work, by combining merits of the sparse model-based optimization method and data-driven deep learning, we propose a deep learning architecture for spectra reconstructi…
With the availability of more powerful computing processors, iterative reconstruction algorithms have recently been successfully implemented as an approach to achieving significant dose reduction in X-ray CT. In this report, we describe our proposal of an adaptive iterative reconstruction algorithm for X-ray CT, that is shown to provide results comparable to those obtained by proprietary algorithms, both in terms of reconstruction accuracy and execution time. Implementation code in the C language is provided, along with example of user interface.
