CoronaryHemodynamics：一种基于OpenFOAM的冠状动脉血流动力学自动化仿真框架
CoronaryHemodynamics: An Automated Simulation Framework for Coronary Artery Hemodynamics Using OpenFOAM
AI总结：
本研究开发了基于OpenFOAM的冠状动脉血流动力学仿真工具包CoronaryHemodynamics，集成自动化仿真流程与生理性边界条件，支持并行计算和多求解器，为相关科研与临床应用提供高效稳健的分析框架。
摘要：
CoronaryHemodynamics是一款基于OpenFOAM平台开发的综合仿真工具包，专门用于冠状动脉血流动力学分析。该工具包集成了一整套仿真准备工具，包括案例自动设置、边界条件配置、计算域网格划分以及CFD求解器，完全支持MPI并行化，可利用OpenFOAM的原生并行计算能力。工具包在主动脉出口和所有冠状动脉血管出口处实施Windkessel边界条件，出口参数可根据心率、收缩压、心肌体积等生理指标自动推导；在主动脉入口处，则根据输入的流量波形施加抛物线流速剖面。CoronaryHemodynamics同时支持稳态求解器和瞬态求解器，可对多种流动条件进行仿真。仿真过程中会记录所有边界处的流量和压力数据，壁面剪切应力、压力场、速度场等输出结果会自动存储，用于详细的后处理与分析。通过自动化仿真流程的关键环节并整合生理性边界条件，CoronaryHemodynamics为科研和临床应用中的冠状动脉血流动力学研究提供了高效且稳健的框架。该工具包可在https://github.com/alundilong/CoronaryHemodynamics获取。
英文摘要：
CoronaryHemodynamics is a comprehensive simulation package developed on the OpenFOAM platform, designed specifically for coronary artery hemodynamics analysis. The package integrates a complete suite of tools for simulation preparation, including automatic case setup, boundary condition configuration, computational domain meshing, and a CFD solver. It fully supports MPI parallelization, leveraging the native parallel computing capabilities of OpenFOAM. The package implements Windkessel boundary conditions at the aorta outlet and all coronary vessel outlets, with outlet parameters automatically derived from physiological metrics such as heart rate, systolic blood pressure, and myocardial volume. At the aorta inlet, a parabolic flow profile is applied based on the input flow rate waveform. CoronaryHemodynamics supports both steady-state and transient solvers, enabling the simulation of various flow conditions. Flow rate and pressure data are recorded at all boundaries during the simulation, and outputs such as wall shear stress, pressure fields, and velocity fields are automatically stored for detailed post-processing and analysis. By automating critical aspects of the simulation pipeline and integrating physiological boundary conditions, CoronaryHemodynamics offers an efficient and robust framework to study coronary hemodynamics in both research and clinical applications. The package can be found at https://github.com/alundilong/CoronaryHemodynamics.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
