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arXiv 2412.05345eess.IVcs.CVcs.LG

基于“分割服务于分类”策略与自监督学习的手部X线图像骨质疏松预测

Osteoporosis Prediction from Hand X-ray Images Using Segmentation-for-Classification and Self-Supervised Learning

Hanyang University(汉阳大学)

Ung Hwang, Chang-Hun Lee, Kijung Yoon

AI总结:

针对骨质疏松DXA筛查渠道有限的问题,提出融合概率U-Net不确定性分割(建模为最优传输问题)与自监督学习的方法,基于手部X线图像实现骨质疏松分类,在192人数据集上验证有效,为外周骨早期筛查提供新路径。

摘要:

骨质疏松症是一种常见的慢性代谢性骨病,由于双能X线吸收法(DXA)等骨密度(BMD)检测手段获取渠道有限,该病常未能得到及时诊断和治疗。为应对这一挑战,当前研究正转向通过分析外周骨区域的替代指标来检测骨质疏松,目标是在不增加额外成本与时间的前提下提高筛查率。本文提出一种利用手与腕部X线图像预测骨质疏松的方法,这类图像获取便捷且成本低廉,但其与基于DXA的检测数据之间的关联尚未得到充分探究。我们采用了一种融合概率U-Net解码器的精细图像分割模型,专门用于捕捉尺骨、桡骨和掌骨分割过程中的预测不确定性。该模型被构建为最优传输(OT)问题,能够更有效地处理图像分割中固有的不确定性。此外,我们引入自监督学习(SSL)方法,无需显式标注即可提取有意义的表征,随后以监督方式完成骨质疏松分类。我们在包含192名受试者的数据集上评估了该方法,将受试者经确认的骨质疏松患病情况与标准DXA检测结果进行交叉验证。该方法取得了优异的分类得分,这种融合不确定性感知分割与自监督学习的方案,是利用视觉技术从外周骨骼部位早期检测骨质疏松的开创性探索。

英文摘要:

Osteoporosis is a widespread and chronic metabolic bone disease that often remains undiagnosed and untreated due to limited access to bone mineral density (BMD) tests like Dual-energy X-ray absorptiometry (DXA). In response to this challenge, current advancements are pivoting towards detecting osteoporosis by examining alternative indicators from peripheral bone areas, with the goal of increasing screening rates without added expenses or time. In this paper, we present a method to predict osteoporosis using hand and wrist X-ray images, which are both widely accessible and affordable, though their link to DXA-based data is not thoroughly explored. We employ a sophisticated image segmentation model that utilizes a mixture of probabilistic U-Net decoders, specifically designed to capture predictive uncertainty in the segmentation of the ulna, radius, and metacarpal bones. This model is formulated as an optimal transport (OT) problem, enabling it to handle the inherent uncertainties in image segmentation more effectively. Further, we adopt a self-supervised learning (SSL) approach to extract meaningful representations without the need for explicit labels, and move on to classify osteoporosis in a supervised manner. Our method is evaluated on a dataset with 192 individuals, cross-referencing their verified osteoporosis conditions against the standard DXA test. With a notable classification score, this integration of uncertainty-aware segmentation and self-supervised learning represents a pioneering effort in leveraging vision-based techniques for the early detection of osteoporosis from peripheral skeletal sites.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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