染色体倒位对黑腹果蝇基因组数据中遗传变异和渐变群模式的影响
The influence of chromosomal inversions on genetic variation and clinal patterns in genomic data of Drosophila melanogaster
AI总结：
本研究提出结合个体与混合重测序数据及种群基因组学工具的分析流程，评估 In(2L)t 与 In(3R)Payne 倒位对全球黑腹果蝇遗传变异、种群结构和渐变群模式的影响。
摘要：
染色体倒位是导致相应基因组区域内基因顺序发生反转的结构突变。由于其对重组模式的影响，它们能够对遗传变异和进化过程产生重大影响。因此，倒位可以作为超基因，使协同适应的基因复合体保持在一起，而这些复合体构成了多种生物中许多复杂表型的遗传基础。在本书章节中，我将介绍一条分析流程，用于研究两种常见的世界性倒位 In(2L)t 和 In(3R)Payne 对全球醋蝇黑腹果蝇种群中全基因组遗传变异和分化的影响。我们将使用单个体重测序数据和混合重测序数据，并结合种群基因组学分析工具，以探究这两种倒位对自然种群中遗传变异、种群结构和渐变群变异的影响。
英文摘要：
Chromosomal inversions are structural mutations resulting in the reversal of the gene order along the corresponding genomic region. Due to their influence on recombination patterns, they can have a major influence on genetic variation and the evolutionary process. Accordingly, inversions can act as supergenes that keep together co-adapted gene complexes that form the genetic basis of many complex phenotypes in diverse organisms. In this book chapter, I will present an analysis pipeline to investigate the influence of two common cosmopolitan inversion, In(2L)t and In(3R)Payne, on genome-wide genetic variation and differentiation in world-wide populations of the vinegar fly Drosophila melanogaster. We will use single-individual and pooled resequencing data in combination with population genomics analysis tools to explore the impact of these two inversions on genetic variation, population structure, and clinal variation in natural populations.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
