癌症放射治疗中的光子计数CT：技术进展与临床获益
Photon-Counting CT in Cancer Radiotherapy: Technological Advances and Clinical Benefits
AI总结：
本综述探讨了光子计数CT（PCCT）在癌症放射治疗中的技术进展与临床获益，指出其通过提升分辨率、降低剂量和优化工作流程，有望变革精准放疗。
摘要：
光子计数计算机断层扫描（PCCT）标志着对传统能量积分探测器（EID）CT系统的重大进展。本综述强调了PCCT卓越的空间和对比度分辨率、降低的辐射剂量以及多能量成像能力，这些优势解决了放射治疗中的关键挑战，如准确勾画肿瘤、精确计算剂量和监测治疗反应。PCCT提升的解剖清晰度增强了肿瘤靶向，同时最小化了对周围健康组织的损伤。此外，金属伪影减少（MAR）和定量成像能力优化了工作流程，实现了自适应放射治疗和放射组学驱动的个性化治疗。近距离放射治疗和放射性药物治疗（RPT）中的新兴临床应用显示出有前景的结果，尽管高成本和软件集成有限等挑战依然存在。随着人工智能（AI）和专用放射治疗包的进步，PCCT有望改变癌症放射治疗的精确性、安全性和有效性，使其成为未来临床实践的关键技术。
英文摘要：
Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and multi-energy imaging capabilities, which address key challenges in radiotherapy, such as accurate tumor delineation, precise dose calculation, and treatment response monitoring. PCCT's improved anatomical clarity enhances tumor targeting while minimizing damage to surrounding healthy tissues. Additionally, metal artifact reduction (MAR) and quantitative imaging capabilities optimize workflows, enabling adaptive radiotherapy and radiomics-driven personalized treatment. Emerging clinical applications in brachytherapy and radiopharmaceutical therapy (RPT) show promising outcomes, although challenges like high costs and limited software integration remain. With advancements in artificial intelligence (AI) and dedicated radiotherapy packages, PCCT is poised to transform precision, safety, and efficacy in cancer radiotherapy, marking it as a pivotal technology for future clinical practice.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
