University of Bristol（布里斯托大学）；Jean Golding Institute（让·戈尔丁研究所）；Massachusetts Institute of Technology（麻省理工学院）；University of Alabama at Birmingham（阿拉巴马大学伯明翰分校）
James Pope, Md Hassanuzzaman, William Chapman, Huw Day, Mingmar Sherpa, Omar Emara, Nirmala Adhikari, Ayush Joshi
Background: Many open-source skin cancer image datasets are the result of clinical trials conducted in countries with lighter skin tones. Due to this tone imbalance, machine learning models derived from these datasets can perform well at detecting skin cancer for lighter skin tones. Any tone bias in these models could introduce fairness concerns and reduce public trust in the artificial intelligence health field.
Methods: We examine a subset of images from the International Skin Imaging Collaboration (ISIC) archive that provide tone information. The subset has a significant tone imbalance. These imbalances could explain a model's tone bias. To address this, we train models using the imbalanced dataset and a balanced dataset to compare against. The datasets are used to train a deep convolutional neural network model to classify the images as malignant or benign. We then evaluate the models' disparate impact, based on selection rate, relative to dark or light skin tone.
Results: Using the imbalanced dataset, we found that the model is significantly better at detecting malignant images in lighter tone resulting in a disparate impact of 0.577. Using the balanced dataset, we found that the model is also significantly better at detecting malignant images in lighter versus darker tones with a disparate impact of 0.684. Using the imbalanced or balanced dataset to train the model still results in a disparate impact well below the standard threshold of 0.80 which suggests the model is biased with respect to skin tone.
Conclusion: The results show that typical skin cancer machine learning models can be tone biased. These results provide evidence that diagnosis or tone imbalance is not the cause of the bias. Other techniques will be necessary to identify and address the bias in these models, an area of future investigation.
Convolutional Neural Networks have demonstrated human-level performance in the classification of melanoma and other skin lesions, but evident performance disparities between differing skin tones should be addressed before widespread deployment. In this work, we propose an efficient yet effective algorithm for automatically labelling the skin tone of lesion images, and use this to annotate the benchmark ISIC dataset. We subsequently use these automated labels as the target for two leading bias unlearning techniques towards mitigating skin tone bias. Our experimental results provide evidence tha…
This study aims to investigate implementing EM and FCM algorithms for skin color extraction. The capabilities of three well-known color spaces, namely, RGB, HSV, and YCbCr for skin-tone extraction are assessed by using statistical modeling of skin tones using EM and FCM algorithms. The results show that utilizing a Gaussian mixture model for parametric modeling of skin tones using EM algorithm works well in HSV color space when all three components of the color vector are used. In spite of discarding the luminance components in YCbCr and HSV color spaces, EM algorithm provides the best results…
Heart rate (HR) is an essential clinical measure for the assessment of cardiorespiratory instability. Since communities of color are disproportionately affected by both COVID-19 and cardiovascular disease, there is a pressing need to deploy contactless HR sensing solutions for high-quality telemedicine evaluations. Existing computer vision methods that estimate HR from facial videos exhibit biased performance against dark skin tones. We present a novel physics-driven algorithm that boosts performance on darker skin tones in our reported data. We assess the performance of our method through the…
Maryland Test Facility（马里兰测试设施中心）；United States Department of Homeland Security, Science and Technology Directorate（美国国土安全部科学与技术局）
With increasing adoption of face recognition systems, it is important to ensure adequate performance of these technologies across demographic groups. Recently, phenotypes such as skin-tone, have been proposed as superior alternatives to traditional race categories when exploring performance differentials. However, there is little consensus regarding how to appropriately measure skin-tone in evaluations of biometric performance or in AI more broadly. In this study, we explore the relationship between face-area-lightness-measures (FALMs) estimated from images and ground-truth skin readings colle…
Stanford School of Medicine（斯坦福大学医学院）；Stanford University（斯坦福大学）；Memorial Sloan Kettering Cancer Center（纪念斯隆凯特琳癌症中心）；Keio University School of Medicine（庆应义塾大学医学院）；Chan-Zuckerberg Biohub（陈-扎克伯格生物中心）
Access to dermatological care is a major issue, with an estimated 3 billion people lacking access to care globally. Artificial intelligence (AI) may aid in triaging skin diseases. However, most AI models have not been rigorously assessed on images of diverse skin tones or uncommon diseases. To ascertain potential biases in algorithm performance in this context, we curated the Diverse Dermatology Images (DDI) dataset-the first publicly available, expertly curated, and pathologically confirmed image dataset with diverse skin tones. Using this dataset of 656 images, we show that state-of-the-art …
Using Computer Vision for Skin Disease Diagnosis in Bangladesh Enhancing Interpretability and Transparency in Deep Learning Models for Skin Cancer Classification
Over the last decades, the incidence of skin cancer, melanoma and non-melanoma, has increased at a continuous rate. In particular for melanoma, the deadliest type of skin cancer, early detection is important to increase patient prognosis. Recently, deep neural networks (DNNs) have become viable to deal with skin cancer detection. In this work, we present a smartphone-based application to assist on skin cancer detection. This application is based on a Convolutional Neural Network(CNN) trained on clinical images and patients demographics, both collected from smartphones. Also, as skin cancer dat…
A Wavelet Guided Attention Module for Skin Cancer Classification with Gradient-based Feature Fusion
Jadavpur University（jadavpur大学）；International Institute of Information Technology（国际信息技术学院）；China University of Mining and Technology（中国矿业大学）；Saint Petersburg Electrotechnical University "LETI"（圣彼得堡电工技术大学“LETI”）
Priyadarshini Institute of Engineering & Technology（普里雅达希尼工程技术学院）
Skin cancer, a major form of cancer, is a critical public health problem with 123,000 newly diagnosed melanoma cases and between 2 and 3 million non-melanoma cases worldwide each year. The leading cause of skin cancer is high exposure of skin cells to UV radiation, which can damage the DNA inside skin cells leading to uncontrolled growth of skin cells. Skin cancer is primarily diagnosed visually employing clinical screening, a biopsy, dermoscopic analysis, and histopathological examination. It has been demonstrated that the dermoscopic analysis in the hands of inexperienced dermatologists may …
Face recognition (FR) systems are fast becoming ubiquitous. However, differential performance among certain demographics was identified in several widely used FR models. The skin tone of the subject is an important factor in addressing the differential performance. Previous work has used modeling methods to propose skin tone measures of subjects across different illuminations or utilized subjective labels of skin color and demographic information. However, such models heavily rely on consistent background and lighting for calibration, or utilize labeled datasets, which are time-consuming to ge…
Dartmouth College（达特茅斯学院）；Dartmouth-Hitchcock Medical Center（达特茅斯-希区柯克医疗中心）；Geisel School of Medicine（盖塞尔医学院）；Metrohealth System（都会医疗系统）；Case Western Reserve University（凯斯西储大学）
Recently, there has been great interest in developing Artificial Intelligence (AI) enabled computer-aided diagnostics solutions for the diagnosis of skin cancer. With the increasing incidence of skin cancers, low awareness among a growing population, and a lack of adequate clinical expertise and services, there is an immediate need for AI systems to assist clinicians in this domain. A large number of skin lesion datasets are available publicly, and researchers have developed AI-based image classification solutions, particularly deep learning algorithms, to distinguish malignant skin lesions fr…
Netaji Subhas University of Technology（内塔吉·苏巴斯理工大学）
Skin cancer is the most common human malignancy(American Cancer Society) which is primarily diagnosed visually, starting with an initial clinical screening and followed potentially by dermoscopic(related to skin) analysis, a biopsy and histopathological examination. Skin cancer occurs when errors (mutations) occur in the DNA of skin cells. The mutations cause the cells to grow out of control and form a mass of cancer cells. The aim of this study was to try to classify images of skin lesions with the help of convolutional neural networks. The deep neural networks show humongous potential for im…
In the last few years, Deep Learning (DL) has been showing superior performance in different modalities of biomedical image analysis. Several DL architectures have been proposed for classification, segmentation, and detection tasks in medical imaging and computational pathology. In this paper, we propose a new DL architecture, the NABLA-N network, with better feature fusion techniques in decoding units for dermoscopic image segmentation tasks. The NABLA-N network has several advances for segmentation tasks. First, this model ensures better feature representation for semantic segmentation with …
Skin cancer is one of the deadly types of cancer and is common in the world. Recently, there has been a huge jump in the rate of people getting skin cancer. For this reason, the number of studies on skin cancer classification with deep learning are increasing day by day. For the growth of work in this area, the International Skin Imaging Collaboration (ISIC) organization was established and they created an open dataset archive. In this study, images were taken from ISIC 2017 Challenge. The skin cancer images taken were preprocessed and data augmented. Later, these images were trained with tran…
United International University（联合国际大学）；The University of Western Australia（西澳大学）；Bangladesh University of Business and Technology（孟加拉国商业与技术大学）；Ahsanullah University of Science and Technology（阿萨努拉科技大学）；Charles Darwin University（查尔斯达尔文大学）
Skin cancer is a major concern to public health, accounting for one-third of the reported cancers. If not detected early, the cancer has the potential for severe consequences. Recognizing the critical need for effective skin cancer classification, we address the limitations of existing models, which are often too large to deploy in areas with limited computational resources. In response, we present a knowledge distillation based approach for creating a lightweight yet high-performing classifier. The proposed solution involves fusing three models, namely ResNet152V2, ConvNeXtBase, and ViT Base,…
Melanoma is one of the most serious skin cancers that can occur in any part of the human skin. Early diagnosis of melanoma lesions will significantly increase their chances of being cured. Improving melanoma segmentation will help doctors or surgical robots remove the lesion more accurately from body parts. Recently, the learning-based segmentation methods achieved desired results in image segmentation compared to traditional algorithms. This study proposes a new approach to improve melanoma skin lesions detection and segmentation by defining a two-step pipeline based on deep learning models. …
Federal University of Espírito Santo, UFES（圣埃斯皮里图联邦大学（UFES））
Skin cancer is a major public health problem around the world. Its early detection is very important to increase patient prognostics. However, the lack of qualified professionals and medical instruments are significant issues in this field. In this context, over the past few years, deep learning models applied to automated skin cancer detection have become a trend. In this paper, we present an overview of the recent advances reported in this field as well as a discussion about the challenges and opportunities for improvement in the current models. In addition, we also present some important as…
University of Perugia（佩鲁贾大学）；University of Florence（佛罗伦萨大学）
Medical data classification is typically a challenging task due to imbalance between classes. In this paper, we propose an approach to classify dermatoscopic images from HAM10000 (Human Against Machine with 10000 training images) dataset, consisting of seven imbalanced types of skin lesions, with good precision and low resources requirements. Classification is done by using a pretrained convolutional neural network. We evaluate the accuracy and performance of the proposal and illustrate possible extensions.
Skin cancer is one of the most common types of cancer around the world. For this reason, over the past years, different approaches have been proposed to assist detect it. Nonetheless, most of them are based only on dermoscopy images and do not take into account the patient clinical information. In this work, first, we present a new dataset that contains clinical images, acquired from smartphones, and patient clinical information of the skin lesions. Next, we introduce a straightforward approach to combine the clinical data and the images using different well-known deep learning models. These m…
Deutsches Forschungszentrum für Künstliche Intelligenz (DFKI)（德国人工智能研究中心）
We describe a software toolbox for the configuration of deep neural networks in the domain of skin cancer classification. The implemented software architecture allows developers to quickly set up new convolutional neural network (CNN) architectures and hyper-parameter configurations. At the same time, the user interface, manageable as a simple spreadsheet, allows non-technical users to explore different configuration settings that need to be explored when switching to different data sets. In future versions, meta leaning frameworks can be added, or AutoML systems that continuously improve over…
Indian Institute of Technology Jodhpur（印度理工学院焦特布尔分校）
Melanoma is a life-threatening form of skin cancer when left undiagnosed at the early stages. Although there are more cases of non-melanoma cancer than melanoma cancer, melanoma cancer is more deadly. Early detection of melanoma is crucial for the timely diagnosis of melanoma cancer and prohibit its spread to distant body parts. Segmentation of skin lesion is a crucial step in the classification of melanoma cancer from the cancerous lesions in dermoscopic images. Manual segmentation of dermoscopic skin images is very time consuming and error-prone resulting in an urgent need for an intelligent…
Tarbiat Modares University（塔比亚特莫达雷斯大学）；Islamic Azad University Science and Research Branch（伊斯兰阿扎德大学科学与研究分校）
At present, cancer is one of the most important health issues in the world. Because early detection and appropriate treatment in cancer are very effective in the recovery and survival of patients, image processing as a diagnostic tool can help doctors to diagnose in the first recognition of cancer. One of the most important steps in diagnosing a skin lesion is to automatically detect the border of the skin image because the accuracy of the next steps depends on it. If these subtleties are identified, they can have a great impact on the diagnosis of the disease. Therefore, there is a good oppor…
More than 3 billion people lack access to care for skin disease. AI diagnostic tools may aid in early skin cancer detection; however most models have not been assessed on images of diverse skin tones or uncommon diseases. To address this, we curated the Diverse Dermatology Images (DDI) dataset - the first publicly available, pathologically confirmed images featuring diverse skin tones. We show that state-of-the-art dermatology AI models perform substantially worse on DDI, with ROC-AUC dropping 29-40 percent compared to the models' original results. We find that dark skin tones and uncommon dis…
National University of Ireland (NUIG)（爱尔兰国立大学（高威））
Technology-assisted platforms provide reliable solutions in almost every field these days. One such important application in the medical field is the skin cancer classification in preliminary stages that need sensitive and precise data analysis. For the proposed study the Kaggle skin cancer dataset is utilized. The proposed study consists of two main phases. In the first phase, the images are preprocessed to remove the clutters thus producing a refined version of training images. To achieve that, a sharpening filter is applied followed by a hair removal algorithm. Different image quality measu…
Indian Institute of Information Technology, Design and Manufacturing, Kancheepuram（印度信息技术与设计制造学院，坎奇普拉姆）
Skin cancer is the most common cancer in the existing world constituting one-third of the cancer cases. Benign skin cancers are not fatal, can be cured with proper medication. But it is not the same as the malignant skin cancers. In the case of malignant melanoma, in its peak stage, the maximum life expectancy is less than or equal to 5 years. But, it can be cured if detected in early stages. Though there are numerous clinical procedures, the accuracy of diagnosis falls between 49% to 81% and is time-consuming. So, dermoscopy has been brought into the picture. It helped in increasing the accur…
Skin cancer affects a large population every year -- automated skin cancer detection algorithms can thus greatly help clinicians. Prior efforts involving deep learning models have high detection accuracy. However, most of the models have a large number of parameters, with some works even using an ensemble of models to achieve good accuracy. In this paper, we investigate a recently proposed pruning technique called Lottery Ticket Hypothesis. We find that iterative pruning of the network resulted in improved accuracy, compared to that of the unpruned network, implying that -- the lottery ticket …
Intelligent Skin Cancer Detection Using a Multispectral Metasurface and a Hybrid
PhD in Communication Engineering, Young Researchers and Elite Club, Islamic Azad University, Urmia Branch, Urmia, Iran（通信工程博士，青年学者与精英俱乐部，伊斯兰 azad 大学乌尔米亚分校，乌尔米亚，伊朗）
Among the different types of skin cancer, melanoma is considered to be the deadliest and is difficult to treat at advanced stages. Detection of melanoma at earlier stages can lead to reduced mortality rates. Desktop-based computer-aided systems have been developed to assist dermatologists with early diagnosis. However, there is significant interest in developing portable, at-home melanoma diagnostic systems which can assess the risk of cancerous skin lesions. Here, we present a smartphone application that combines image capture capabilities with preprocessing and segmentation to extract the As…
Institute for Molecular Bioscience, The University of Queensland（昆士兰大学分子生物科学研究所）；MyLab Pathology（迈莱博病理实验室）
Pathologists have a rich vocabulary with which they can describe all the nuances of cellular morphology. In their world, there is a natural pairing of images and words. Recent advances demonstrate that machine learning models can now be trained to learn high-quality image features and represent them as discrete units of information. This enables natural language, which is also discrete, to be jointly modelled alongside the imaging, resulting in a description of the contents of the imaging. Here we present experiments in applying discrete modelling techniques to the problem domain of non-melano…
Fitzpatrick Thresholding for Skin Image Segmentation
Independent Researcher, San Francisco, CA, USA（独立研究者）；Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA（韦格尔斯医学与外科学院，哥伦比亚大学）；University of Mississippi Medical Center, Jackson, MS, USA（密西西比大学医学中心）；Division of Dermatology, The University of Texas at Austin, Dell Medical School, Austin, Texas（皮肤科部门，德克萨斯大学奥斯汀分校，德克萨斯医学学院）
Beheshti University（贝赫什提大学）；University of Tehran（德黑兰大学）；Isfahan University of Technology（伊斯法罕理工大学）；Deakin University（迪肯大学）
Deep learning (DL) models have received particular attention in medical imaging due to their promising pattern recognition capabilities. However, Deep Neural Networks (DNNs) require a huge amount of data, and because of the lack of sufficient data in this field, transfer learning can be a great solution. DNNs used for disease diagnosis meticulously concentrate on improving the accuracy of predictions without providing a figure about their confidence of predictions. Knowing how much a DNN model is confident in a computer-aided diagnosis model is necessary for gaining clinicians' confidence and …
Australian e-Health Research Centre, CSIRO（澳大利亚联邦科学与工业研究组织电子健康研究中心）
Generative learning is a powerful tool for representation learning, and shows particular promise for problems in biomedical imaging. However, in this context, sampling from the distribution is secondary to finding representations of real images, which often come with labels and explicitly represent the content and quality of the target distribution. It remains difficult to faithfully reconstruct images from generative models, particularly those as complex as histological images. In this work, two existing methods (autoencoders and adversarial latent autoencoders) are combined in attempt to imp…
Hybrid Ensemble of Segmentation-Assisted Classification and GBDT for Skin Cancer Detection with Engineered Metadata and Synthetic Lesions from ISIC 2024 Non-Dermoscopic 3D-TBP Images
FH Joanneum University of Applied Sciences（约阿内姆应用科学大学）
Skin cancer is the most common cancer worldwide, with melanoma being the deadliest form. Dermoscopy is a skin imaging modality that has shown an improvement in the diagnosis of skin cancer compared to visual examination without support. We evaluate the current state of the art in the classification of dermoscopic images based on the ISIC-2019 Challenge for the classification of skin lesions and current literature. Various deep neural network architectures pre-trained on the ImageNet data set are adapted to a combined training data set comprised of publicly available dermoscopic and clinical im…
Optimizing Deep Learning for Skin Cancer Classification: A Computationally Efficient CNN with Minimal Accuracy Trade-Off
Dhaka University of Engineering & Technology（达卡工程与技术大学）；Samsung Austin Research Center（三星奥斯汀研究中心）；Federation University Australia（联邦大学澳大利亚分校）；Woosong University（沃斯通大学）；Graduate Center, CUNY（纽约大学研究生中心）
Information Technology University（信息技术大学）；The Home Depot（家得宝）；Central Park Medical College（中央公园医学院）
Deep neural networks have shown promising results in disease detection and classification using medical image data. However, they still suffer from the challenges of handling real-world scenarios especially reliably detecting out-of-distribution (OoD) samples. We propose an approach to robustly classify OoD samples in skin and malaria images without the need to access labeled OoD samples during training. Specifically, we use metric learning along with logistic regression to force the deep networks to learn much rich class representative features. To guide the learning process against the OoD e…
Shri Guru Gobind Singhji Institute of Engineering and Technology（什里·古鲁·戈宾德·辛格吉工程技术学院）
Automatic lesion analysis is critical in skin cancer diagnosis and ensures effective treatment. The computer aided diagnosis of such skin cancer in dermoscopic images can significantly reduce the clinicians workload and help improve diagnostic accuracy. Although researchers are working extensively to address this problem, early detection and accurate identification of skin lesions remain challenging. This research focuses on a two step framework for skin lesion segmentation followed by classification for lesion analysis. We explored the effectiveness of deep convolutional neural network based …
