Recent work has focused on nonparametric estimation of conditional treatment effects, but inference has remained relatively unexplored. We propose a class of nonparametric tests for both quantitative and qualitative treatment effect heterogeneity. The tests can incorporate a variety of structured assumptions on the conditional average treatment effect, allow for both continuous and discrete covariates, and do not require sample splitting to obtain a tractable asymptotic null distribution. Furthermore, we show how the tests are tailored to detect alternatives where the population impact of adopting a personalized decision rule differs from using a rule that discards covariates. The proposal is thus relevant for guiding treatment policies. The utility of the proposal is borne out in simulation studies and a re-analysis of an AIDS clinical trial.
The participants in randomized trials and other studies used for causal inference are often not representative of the populations seen by clinical decision-makers. To account for differences between populations, researchers may consider standardizing results to a target population. We discuss several different types of homogeneity conditions that are relevant for standardization: Homogeneity of effect measures, homogeneity of counterfactual outcome state transition parameters, and homogeneity of counterfactual distributions. Each of these conditions can be used to show that a particular standa…
Regional frequency analysis is an important tool to properly estimate hydrological characteristics at ungauged or partially gauged sites in order to prevent hydrological disasters. The delineation of homogeneous groups of sites is an important first step in order to transfer information and obtain accurate quantile estimates at the target site. The Hosking-Wallis homogeneity test is usually used to test the homogeneity of the selected sites. Despite its usefulness and good power, it presents some drawbacks including the subjective choice of a parametric distribution for the data and a poorly j…
Many panel data have the latent subgroup effect on individuals, and it is important to correctly identify these groups since the efficiency of resulting estimators can be improved significantly by pooling the information of individuals within each group. However, the currently assumed parametric and semiparametric relationship between the response and predictors may be misspecified, which leads to a wrong grouping result, and the nonparametric approach hence can be considered to avoid such mistakes. Moreover, the response may depend on predictors in different ways at various quantile levels, a…
Basketball shot location data provide valuable summary information regarding players to coaches, sports analysts, fans, statisticians, as well as players themselves. Represented by spatial points, such data are naturally analyzed with spatial point process models. We present a novel nonparametric Bayesian method for learning the underlying intensity surface built upon a combination of Dirichlet process and Markov random field. Our method has the advantage of effectively encouraging local spatial homogeneity when estimating a globally heterogeneous intensity surface. Posterior inferences are pe…
Statistical models of unobserved heterogeneity are typically formalized as mixtures of simple parametric models and interest naturally focuses on testing for homogeneity versus general mixture alternatives. Many tests of this type can be interpreted as $C(α)$ tests, as in Neyman (1959), and shown to be locally, asymptotically optimal. These $C(α)$ tests will be contrasted with a new approach to likelihood ratio testing for general mixture models. The latter tests are based on estimation of general nonparametric mixing distribution with the Kiefer and Wolfowitz (1956) maximum likelihood estimat…
We propose a novel nonparametric Bayesian IRT model in this paper by introducing the clustering effect at question level and further assume heterogeneity at examinee level under each question cluster, characterized by the mixture of Binomial distributions. The main contribution of this work is threefold: (1) We demonstrate that the model is identifiable. (2) The clustering effect can be captured asymptotically and the parameters of interest that measure the proficiency of examinees in solving certain questions can be estimated at a root n rate (up to a log term). (3) We present a tractable sam…
Nonseparable panel models are important in a variety of economic settings, including discrete choice. This paper gives identification and estimation results for nonseparable models under time homogeneity conditions that are like "time is randomly assigned" or "time is an instrument." Partial identification results for average and quantile effects are given for discrete regressors, under static or dynamic conditions, in fully nonparametric and in semiparametric models, with time effects. It is shown that the usual, linear, fixed-effects estimator is not a consistent estimator of the identified …
Average Treatment Effect Estimation with Non-binary Instrumental Variables
University of Toronto（多伦多大学）；Shanghai Jiao Tong University（上海交通大学）；University of Ottawa（渥太华大学）；Princess Margaret Cancer Centre, University Health Network（公主玛格丽特癌症中心，联合健康网络）
This paper considers identification and estimation of ceteris paribus effects of continuous regressors in nonseparable panel models with time homogeneity. The effects of interest are derivatives of the average and quantile structural functions of the model. We find that these derivatives are identified with two time periods for "stayers", i.e. for individuals with the same regressor values in two time periods. We show that the identification results carry over to models that allow location and scale time effects. We propose nonparametric series methods and a weighted bootstrap scheme to estima…
Researchers are often interested in treatment effects on outcomes that are only defined conditional on a post-treatment event status. For example, in a study of the effect of different cancer treatments on quality of life at end of follow-up, the quality of life of individuals who die during the study is undefined. In these settings, a naive contrast of outcomes conditional on the post-treatment variable is not an average causal effect, even in a randomized experiment. Therefore the effect in the principal stratum of those who would have the same value of the post-treatment variable regardless…
Nonparametric tests via kernel embedding of distributions have witnessed a great deal of practical successes in recent years. However, statistical properties of these tests are largely unknown beyond consistency against a fixed alternative. To fill in this void, we study here the asymptotic properties of goodness-of-fit, homogeneity and independence tests using Gaussian kernels, arguably the most popular and successful among such tests. Our results provide theoretical justifications for this common practice by showing that tests using Gaussian kernel with an appropriately chosen scaling parame…
Blessing from Human-AI Interaction: Super Reinforcement Learning in Confounded Environments
Department of Mathematical Sciences, University of Texas at Dallas（德克萨斯大学达拉斯分校数学科学系）；Department of Statistics, London School of Economics and Political Science（伦敦政治经济学院统计系）；Department of Decision Sciences, George Washington University（乔治华盛顿大学决策科学系）
Motivated by increasing pressure for decision makers to shorten the time required to evaluate the efficacy of a treatment such that treatments deemed safe and effective can be made publicly available, there has been substantial recent interest in using an earlier or easier to measure surrogate marker, $S$, in place of the primary outcome, $Y$. To validate the utility of a surrogate marker in these settings, a commonly advocated measure is the proportion of treatment effect on the primary outcome that is explained by the treatment effect on the surrogate marker (PTE). Model based and model free…
