基于光纤微探针的内镜傅里叶变换红外光谱技术
Endoscopic Fourier-transform infrared spectroscopy through a fiber microprobe
AI总结：
针对FTIR在强红外吸收介质（如液体溶液）中定量能力受限的问题，开发了可插入液体的红外光纤微探针及内镜FTIR方法，通过水的基准测试验证其性能，为体相液体的内镜化学分析提供新途径。
摘要：
傅里叶变换红外光谱（FTIR）是一种强大的分析方法，不仅可用于固体、液体和气体物质的化学鉴定，还能对其浓度进行定量分析。然而，当分析物被强红外吸收介质（如液体溶液）包围时，FTIR的化学定量能力会受到显著阻碍。为克服这一限制，我们开发了一种可插入液体介质的红外光纤微探针，能在感兴趣的点获取完整FTIR光谱。为基准测试该内镜FTIR方法，我们将微探针插入覆盖ZnSe基底的大量水中，测量水的红外透射率随探针-基底距离的变化。所得振动模式、整体透射率与z轴分布、定量吸收系数及微区z截面红外透射光谱均与水的标准红外吸收特性一致。该结果为体相液体溶液内的内镜化学分析铺平了道路，有望应用于多种生物、化学和电化学系统。
英文摘要：
Fourier-transform infrared spectroscopy (FTIR) is a powerful analytical method for not only the chemical identification of solid, liquid, and gas species, but also the quantification of their concentration. However, the chemical quantification capability of FTIR is significantly hindered when the analyte is surrounded by a strong IR absorbing medium, such as liquid solutions. To overcome this limit, here we develop an IR fiber microprobe that can be inserted into liquid medium, and obtain full FTIR spectra at points of interest. To benchmark this endoscopic FTIR method, we insert the microprobe into bulk water covering a ZnSe substrate and measure the IR transmittance of water as a function of the probe-substrate distance. The obtained vibrational modes, overall transmittance vs z profiles, quantitative absorption coefficients, and micro z-section IR transmittance spectra are all consistent with the standard IR absorption properties of water. The results pave the way for endoscopic chemical profiling inside bulk liquid solutions, promising for applications in many biological, chemical, and electrochemical systems.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
