Cardiac Magnetic Resonance Imaging (CMR) is the gold standard for diagnosing cardiovascular diseases. Clinical diagnoses predominantly rely on magnitude-only Digital Imaging and Communications in Medicine (DICOM) images, omitting crucial phase information that might provide additional diagnostic benefits. In contrast, k-space is complex-valued and encompasses both magnitude and phase information, while humans cannot directly perceive. In this work, we propose KMAE, a Transformer-based model specifically designed to process k-space data directly, eliminating conventional intermediary conversion steps to the image domain. KMAE can handle critical cardiac disease classification, relevant phenotype regression, and cardiac morphology segmentation tasks. We utilize this model to investigate the potential of k-space-based diagnosis in cardiac MRI. Notably, this model achieves competitive classification and regression performance compared to image-domain methods e.g. Masked Autoencoders (MAEs) and delivers satisfactory segmentation performance with a myocardium dice score of 0.884. Last but not least, our model exhibits robust performance with consistent results even when the k-space is 8* undersampled. We encourage the MR community to explore the untapped potential of k-space and pursue end-to-end, automated diagnosis with reduced human intervention.
In most medical image processing tasks, the orientation of an image would affect computing result. However, manually reorienting images wastes time and effort. In this paper, we study the problem of recognizing orientation in cardiac MRI and using deep neural network to solve this problem. For multiple sequences and modalities of MRI, we propose a transfer learning strategy, which adapts our proposed model from a single modality to multiple modalities. We also propose a prediction method that uses voting. The results shows that deep neural network is an effective way in recognition of cardiac …
Zhejiang University（浙江大学）；University of Notre Dame（圣母大学）
Automatic segmentation of cardiac magnetic resonance imaging (MRI) facilitates efficient and accurate volume measurement in clinical applications. However, due to anisotropic resolution and ambiguous border (e.g., right ventricular endocardium), existing methods suffer from the degradation of accuracy and robustness in 3D cardiac MRI video segmentation. In this paper, we propose a novel Deformable U-Net (DeU-Net) to fully exploit spatio-temporal information from 3D cardiac MRI video, including a Temporal Deformable Aggregation Module (TDAM) and a Deformable Global Position Attention (DGPA) net…
In this paper, we study the problem of imaging orientation in cardiac MRI, and propose a framework to categorize the orientation for recognition and standardization via deep neural networks. The method uses a new multi-tasking strategy, where both the tasks of cardiac segmentation and orientation recognition are simultaneously achieved. For multiple sequences and modalities of MRI, we propose a transfer learning strategy, which adapts our proposed model from a single modality to multiple modalities. We embed the orientation recognition network in a Cardiac MRI Orientation Adjust Tool, i.e., CM…
University College London（伦敦大学学院）；Centre for Medical Image Computing（医学图像计算中心）
Accurate segmentation of the right ventricle (RV) is a crucial step in the assessment of the ventricular structure and function. Yet, due to its complex anatomy and motion segmentation of the RV has not been as largely studied as the left ventricle. This paper presents a fully automatic method for the segmentation of the RV in cardiac magnetic resonance images (MRI). The method uses a coarse-to-fine segmentation strategy in combination with a multi-atlas propagation segmentation framework. Based on a cross correlation metric, our method selects the best atlases for propagation allowing the ref…
United Imaging Intelligence（联影智能）；UIH America, Inc.（联影美国公司）；United Imaging Healthcare（联影医疗）
Retrospectively gated cine (retro-cine) MRI is the clinical standard for cardiac functional analysis. Deep learning (DL) based methods have been proposed for the reconstruction of highly undersampled MRI data and show superior image quality and magnitude faster reconstruction time than CS-based methods. Nevertheless, it remains unclear whether DL reconstruction is suitable for cardiac function analysis. To address this question, in this study we evaluate and compare the cardiac functional values (EDV, ESV and EF for LV and RV, respectively) obtained from highly accelerated MRI acquisition usin…
Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University（复旦大学类脑智能科学与技术研究院）
In this paper, the problem of orientation correction in cardiac MRI images is investigated and a framework for orientation recognition via deep neural networks is proposed. For multi-modality MRI, we introduce a transfer learning strategy to transfer our proposed model from single modality to multi-modality. We embed the proposed network into the orientation correction command-line tool, which can implement orientation correction on 2D DICOM and 3D NIFTI images. Our source code, network models and tools are available at https://github.com/Jy-stdio/MSCMR_orient/
Personalized 4D Whole Heart Geometry Reconstruction from Cine MRI for Cardiac Digital Twins
Department of Biomedical Engineering, National University of Singapore, Singapore（新加坡国立大学生物医学工程系）；School of Data Science, Fudan University, Shanghai, China（复旦大学数据科学学院）；Department of Engineering Science, University of Oxford, Oxford, UK（牛津大学工程科学系）；Department of Medicine, National University of Singapore, Singapore（新加坡国立大学医学系）；Department of Cardiology, National University Heart Centre Singapore, Singapore（新加坡国立心脏中心心内科部）
University of Notre Dame（圣母大学）；IBM Thomas J. Watson Research Center（IBM托马斯·J·沃森研究中心）；Guangdong General Hospital（广东省人民医院）
Cardiac magnetic resonance imaging (MRI) is an essential tool for MRI-guided surgery and real-time intervention. The MRI videos are expected to be segmented on-the-fly in real practice. However, existing segmentation methods would suffer from drastic accuracy loss when modified for speedup. In this work, we propose Multiscale Statistical U-Net (MSU-Net) for real-time 3D MRI video segmentation in cardiac surgical guidance. Our idea is to model the input samples as multiscale canonical form distributions for speedup, while the spatio-temporal correlation is still fully utilized. A parallel stati…
University of Notre Dame（圣母大学）；Guangdong Provincial People’s Hospital（广东省人民医院）；IBM Thomas J. Watson Research Center（IBM托马斯·J·沃森研究中心）
Real-time cine magnetic resonance imaging (MRI) plays an increasingly important role in various cardiac interventions. In order to enable fast and accurate visual assistance, the temporal frames need to be segmented on-the-fly. However, state-of-the-art MRI segmentation methods are used either offline because of their high computation complexity, or in real-time but with significant accuracy loss and latency increase (causing visually noticeable lag). As such, they can hardly be adopted to assist visual guidance. In this work, inspired by a new interpretation of Independent Component Analysis …
University of Sherbrooke（舍布鲁克大学）；Université de Bourgogne Franche-Comté（勃艮第-弗朗什孔泰大学）；CArdiac Simulation & Imaging Software（心脏模拟与成像软件公司）；Université de Lyon（里昂大学）
Recent publications have shown that the segmentation accuracy of modern-day convolutional neural networks (CNN) applied on cardiac MRI can reach the inter-expert variability, a great achievement in this area of research. However, despite these successes, CNNs still produce anatomically inaccurate segmentations as they provide no guarantee on the anatomical plausibility of their outcome, even when using a shape prior. In this paper, we propose a cardiac MRI segmentation method which always produces anatomically plausible results. At the core of the method is an adversarial variational autoencod…
Automatic segmentation of myocardial contours and relevant areas like infraction and no-reflow is an important step for the quantitative evaluation of myocardial infarction. In this work, we propose a cascaded convolutional neural network for automatic myocardial infarction segmentation from delayed-enhancement cardiac MRI. We first use a 2D U-Net to focus on the intra-slice information to perform a preliminary segmentation. After that, we use a 3D U-Net to utilize the volumetric spatial information for a subtle segmentation. Our method is evaluated on the MICCAI 2020 EMIDEC challenge dataset …
Cardiac Magnetic Resonance Imaging (MRI) plays an important role in the analysis of cardiac function. However, the acquisition is often accompanied by motion artefacts because of the difficulty of breath-hold, especially for acute symptoms patients. Therefore, it is essential to assess the quality of cardiac MRI for further analysis. Time-consuming manual-based classification is not conducive to the construction of an end-to-end computer aided diagnostic system. To overcome this problem, an automatic cardiac MRI quality estimation framework using ensemble and transfer learning is proposed in t…
Magnetic Resonance Imaging (MRI) has evolved as a clinical standard-of-care imaging modality for cardiac morphology, function assessment, and guidance of cardiac interventions. All these applications rely on accurate extraction of the myocardial tissue and blood pool from the imaging data. Here we propose a framework for left ventricle (LV) segmentation from cardiac cine-MRI. First, we segment the LV blood pool using iterative graph cuts, and subsequently use this information to segment the myocardium. We formulate the segmentation procedure as an energy minimization problem in a graph subject…
Guangdong Cardiovascular Institute（广东省心血管病研究所）；Guangdong Provincial People’s Hospital（广东省人民医院）；Guangdong Academy of Medical Sciences（广东省医学科学院）；University of Notre Dame（圣母大学）
Coronary artery disease (CAD) is the most common cause of death globally, and its diagnosis is usually based on manual myocardial segmentation of Magnetic Resonance Imaging (MRI) sequences. As the manual segmentation is tedious, time-consuming and with low applicability, automatic myocardial segmentation using machine learning techniques has been widely explored recently. However, almost all the existing methods treat the input MRI sequences independently, which fails to capture the temporal information between sequences, e.g., the shape and location information of the myocardium in sequences …
National Heart and Lung Institute, Imperial College London（帝国理工学院国家心肺研究所）；Imperial College London（帝国理工学院）；Royal Brompton Hospital（皇家布朗普顿医院）
Temporal patterns of cardiac motion provide important information for cardiac disease diagnosis. This pattern could be obtained by three-directional CINE multi-slice left ventricular myocardial velocity mapping (3Dir MVM), which is a cardiac MR technique providing magnitude and phase information of the myocardial motion simultaneously. However, long acquisition time limits the usage of this technique by causing breathing artifacts, while shortening the time causes low temporal resolution and may provide an inaccurate assessment of cardiac motion. In this study, we proposed a frame synthesis al…
Reconstruction of Cardiac Cine MRI Using Motion-Guided Deformable Alignment and Multi-Resolution Fusion
School of Health Science and Engineering, University of Shanghai for Science and Technology（上海理工大学健康科学与工程学院）；ToolSensing Technologies Co., Ltd（拓深科技有限公司）；School of Medical Instruments, Shanghai University of Medicine and Health Sciences（上海健康医学院医疗器械学院）；Shanghai Key Laboratory of Multidimensional Information Processing, School of Communication & Electronic Engineering, East China Normal University（华东师范大学通信与电子工程学院多维信息处理上海重点实验室）
Imperial College London（帝国理工学院）；Royal Brompton Hospital（皇家布朗普顿医院）
Segmentation of cardiac fibrosis and scar are essential for clinical diagnosis and can provide invaluable guidance for the treatment of cardiac diseases. Late Gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) has been successful for its efficacy in guiding the clinical diagnosis and treatment reliably. For LGE CMR, many methods have demonstrated success in accurately segmenting scarring regions. Co-registration with other non-contrast-agent (non-CA) modalities, balanced steady-state free precession (bSSFP) and cine magnetic resonance imaging (MRI) for example, can further en…
In recent years, convolutional neural networks have demonstrated promising performance in a variety of medical image segmentation tasks. However, when a trained segmentation model is deployed into the real clinical world, the model may not perform optimally. A major challenge is the potential poor-quality segmentations generated due to degraded image quality or domain shift issues. There is a timely need to develop an automated quality control method that can detect poor segmentations and feedback to clinicians. Here we propose a novel deep generative model-based framework for quality control …
Towards Cardiac MRI Foundation Models: Comprehensive Visual-Tabular Representations for Whole-Heart Assessment and Beyond
School of Computation, Information and Technology, Technical University of Munich（慕尼黑工业大学计算、信息与技术学院）；School of Medicine, Klinikum Rechts der Isar, Technical University of Munich（慕尼黑工业大学伊萨尔河畔右岸医院医学院）；Data Science Institute, Imperial College London（帝国理工学院数据科学研究所）；Department of Computing, Imperial College London（帝国理工学院计算系）；Department of Computer Science, University of Sheffield（谢菲尔德大学计算机科学系）；Department of Quantitative Biomedicine, University of Zurich（苏黎世大学定量生物医学系）
Université Côte d’Azur（蔚蓝海岸大学）；Inria（法国国家信息与自动化研究所）；William Harvey Research Institute（威廉·哈维研究所）；Queen Mary University of London（伦敦玛丽女王大学）；Barts Health NHS Trust（巴茨健康国民保健信托基金）
We perform unsupervised analysis of image-derived shape and motion features extracted from 3822 cardiac 4D MRIs of the UK Biobank. First, with a feature extraction method previously published based on deep learning models, we extract from each case 9 feature values characterizing both the cardiac shape and motion. Second, a feature selection is performed to remove highly correlated feature pairs. Third, clustering is carried out using a Gaussian mixture model on the selected features. After analysis, we identify two small clusters which probably correspond to two pathological categories. Furth…
School of Biomedical Engineering & Imaging Sciences, King’s College London, UK（伦敦国王学院生物医学工程与成像科学学院）；Technical University of Munich, Germany（慕尼黑工业大学）；Biomedical Image Analysis Group, Imperial College London, UK（帝国理工学院生物医学图像分析组）；Department of Adult and Paediatric Cardiology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK（盖伊和圣托马斯国民健康服务信托基金会成人及儿科心脏病科）；Coimbra Institute for Biomedical Imaging and Translational Research, University of Coimbra, Portugal（科英布拉大学科英布拉生物医学成像与转化研究学院）；Helmholtz Center Munich, Germany（慕尼黑亥姆霍兹中心）
Cine cardiac MRI is routinely acquired for the assessment of cardiac health, but the imaging process is slow and typically requires several breath-holds to acquire sufficient k-space profiles to ensure good image quality. Several undersampling-based reconstruction techniques have been proposed during the last decades to speed up cine cardiac MRI acquisition. However, the undersampling factor is commonly fixed to conservative values before acquisition to ensure diagnostic image quality, potentially leading to unnecessarily long scan times. In this paper, we propose an end-to-end quality-aware c…
Personalized Topology-Informed Localization of Standard 12-Lead ECG Electrode Placement from Incomplete Cardiac MRIs for Efficient Cardiac Digital Twins
School of Electronics & Computer Science, University of Southampton（南安普顿大学电子与计算机科学学院）；University of Oxford（牛津大学）；National University of Singapore（新加坡国立大学）；School of Biomedical Engineering and Imaging Sciences, Kings College London（伦敦国王学院生物医学工程与影像科学学院）
We introduce a model-based reconstruction framework with deep learned (DL) and smoothness regularization on manifolds (STORM) priors to recover free breathing and ungated (FBU) cardiac MRI from highly undersampled measurements. The DL priors enable us to exploit the local correlations, while the STORM prior enables us to make use of the extensive non-local similarities that are subject dependent. We introduce a novel model-based formulation that allows the seamless integration of deep learning methods with available prior information, which current deep learning algorithms are not capable of. …
Massachusetts General Hospital（麻省总医院）；Harvard Medical School（哈佛医学院）；University of Southern California（南加州大学）
Cardiac cine magnetic resonance imaging (MRI) has been used to characterize cardiovascular diseases (CVD), often providing a noninvasive phenotyping tool.~While recently flourished deep learning based approaches using cine MRI yield accurate characterization results, the performance is often degraded by small training samples. In addition, many deep learning models are deemed a ``black box," for which models remain largely elusive in how models yield a prediction and how reliable they are. To alleviate this, this work proposes a lightweight successive subspace learning (SSL) framework for CVD …
Automatic segmentation of the heart cavity is an essential task for the diagnosis of cardiac diseases. In this paper, we propose a semi-supervised segmentation setup for leveraging unlabeled data to segment Left-ventricle, Right-ventricle, and Myocardium. We utilize an enhanced version of residual U-Net architecture on a large-scale cardiac MRI dataset. Handling the class imbalanced data issue using dice loss, the enhanced supervised model is able to achieve better dice scores in comparison with a vanilla U-Net model. We applied several augmentation techniques including histogram matching to i…
KP-INR: A Dual-Branch Implicit Neural Representation Model for Cardiac Cine MRI Reconstruction
Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands（莱顿大学医学中心放射科）；Cardiologs, Philips, Paris, France（法国巴黎Philips心血管部门）；Faculty of Computer Science, Eindhoven University of Technology, Eindhoven, The Netherlands（埃因霍温理工大学计算机科学学院）；Philips Innovative Technologies, Hamburg, Germany（德国汉堡Philips创新技术）
Rutgers University（罗格斯大学）；United Imaging Intelligence（联影智能）；University of Illinois at Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）
Accurate estimation of shape thickness from medical images is crucial in clinical applications. For example, the thickness of myocardium is one of the key to cardiac disease diagnosis. While mathematical models are available to obtain accurate dense thickness estimation, they suffer from heavy computational overhead due to iterative solvers. To this end, we propose novel methods for dense thickness estimation, including a fast solver that estimates thickness from binary annular shapes and an end-to-end network that estimates thickness directly from raw cardiac images.We test the proposed model…
Nanjing University of Science and Technology（南京理工大学）
Automatic evaluation of myocardium and pathology plays an important role in the quantitative analysis of patients suffering from myocardial infarction. In this paper, we present a cascaded convolutional neural network framework for myocardial infarction segmentation and classification in delayed-enhancement cardiac MRI. Specifically, we first use a 2D U-Net to segment the whole heart, including the left ventricle and the myocardium. Then, we crop the whole heart as a region of interest (ROI). Finally, a new 2D U-Net is used to segment the infraction and no-reflow areas in the whole heart ROI. …
CineMesh4D: Personalized 4D Whole Heart Reconstruction from Sparse Cine MRI
Department of Biomedical Engineering, National University of Singapore, Singapore（新加坡国立大学生物医学工程系）；School of Automation, Southeast University, Nanjing, China（东南大学自动化学院）；Department of Medicine, National University of Singapore, Singapore（新加坡国立大学医学系）；Department of Cardiology, National University Heart Centre Singapore, Singapore（新加坡国立心脏中心心内科部）
本文提出 CineMesh4D，一种端到端的 4D 全心脏重建方法，通过跨域映射从多视角 2D cine MRI 直接重建患者特定的全心脏网格，提升重建质量和运动一致性。
Amsterdam UMC, University of Amsterdam（阿姆斯特丹大学阿姆斯特丹大学医学中心）；Amsterdam University Medical Center, University of Amsterdam（阿姆斯特丹大学阿姆斯特丹大学医学中心）；University Medical Center Utrecht（乌得勒支大学医学中心）
Segmentation of cardiac anatomical structures in cardiac magnetic resonance images (CMRI) is a prerequisite for automatic diagnosis and prognosis of cardiovascular diseases. To increase robustness and performance of segmentation methods this study combines automatic segmentation and assessment of segmentation uncertainty in CMRI to detect image regions containing local segmentation failures. Three state-of-the-art convolutional neural networks (CNN) were trained to automatically segment cardiac anatomical structures and obtain two measures of predictive uncertainty: entropy and a measure deriv…
Low-rank tensor models have been applied in accelerating dynamic magnetic resonance imaging (dMRI). Recently, a new tensor nuclear norm based on t-SVD has been proposed and applied to tensor completion. Inspired by the different properties of the tensor nuclear norm (TNN) and the Casorati matrix nuclear norm (MNN), we introduce a combined TNN and Casorati MNN regularizations framework to reconstruct dMRI, which we term as TMNN. The proposed method simultaneously exploits the spatial structure and the temporal correlation of the dynamic MR data. The optimization problem can be efficiently solve…
Automated cardiac segmentation from magnetic resonance imaging datasets is an essential step in the timely diagnosis and management of cardiac pathologies. We propose to tackle the problem of automated left and right ventricle segmentation through the application of a deep fully convolutional neural network architecture. Our model is efficiently trained end-to-end in a single learning stage from whole-image inputs and ground truths to make inference at every pixel. To our knowledge, this is the first application of a fully convolutional neural network architecture for pixel-wise labeling in ca…
Personalized 3D Myocardial Infarct Geometry Reconstruction from Cine MRI with Explicit Cardiac Motion Modeling
Department of Biomedical Engineering, National University of Singapore, Singapore（新加坡国立大学生物医学工程系）；Department of Computer Science, National University of Singapore, Singapore（新加坡国立大学计算机科学系）；Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand（奥克兰大学生物工程研究所）；School of Biomedical Engineering and Imaging Sciences, King’s College London, UK（伦敦国王学院生物医学工程与成像科学学校）；Department of Medicine, National University of Singapore, Singapore（新加坡国立大学医学系）；Department of Cardiology, National University Heart Centre Singapore, Singapore（新加坡国立心脏中心心血管科）
University of Bourgogne Franche-Comte（勃艮第-弗朗什-孔泰大学）；CASIS inc.（CASIS公司）；University of Sherbrooke（舍布鲁克大学）；University Hospital of Dijon（第戎大学医院）
Deep learning methods are the de-facto solutions to a multitude of medical image analysis tasks. Cardiac MRI segmentation is one such application which, like many others, requires a large number of annotated data so a trained network can generalize well. Unfortunately, the process of having a large number of manually curated images by medical experts is both slow and utterly expensive. In this paper, we set out to explore whether expert knowledge is a strict requirement for the creation of annotated datasets that machine learning can successfully train on. To do so, we gauged the performance o…
School of Electronic Information and Communications, Huazhong University of Science and Technology（华中科技大学电子信息与通信学院）；Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology（华中科技大学同济医学院附属协和医院放射科）；Hubei Province Key Laboratory of Molecular Imaging（湖北省分子影像重点实验室）；HUST-HW Joint Innovation Lab（华中科技大学-华为联合创新实验室）
Cardiac MRI segmentation plays a crucial role in clinical diagnosis for evaluating personalized cardiac performance parameters. Due to the indistinct boundaries and heterogeneous intensity distributions in the cardiac MRI, most existing methods still suffer from two aspects of challenges: inter-class indistinction and intra-class inconsistency. To tackle these two problems, we propose a novel method to exploit the directional feature maps, which can simultaneously strengthen the differences between classes and the similarities within classes. Specifically, we perform cardiac segmentation and l…
Université de Sherbrooke（舍布鲁克大学）；Xiamen University（厦门大学）；Centre Antoine Lacassagne（安托万·拉卡萨涅中心）；Université de Bourgogne Franche-Comté（勃艮第-弗朗什-孔泰大学）
In this paper, we propose a fully automatic MRI cardiac segmentation method based on a novel deep convolutional neural network (CNN) designed for the 2017 ACDC MICCAI challenge. The novelty of our network comes with its embedded shape prior and its loss function tailored to the cardiac anatomy. Our model includes a cardiac centerof-mass regression module which allows for an automatic shape prior registration. Also, since our method processes raw MR images without any manual preprocessing and/or image cropping, our CNN learns both high-level features (useful to distinguish the heart from other …
We propose a method to classify cardiac pathology based on a novel approach to extract image derived features to characterize the shape and motion of the heart. An original semi-supervised learning procedure, which makes efficient use of a large amount of non-segmented images and a small amount of images segmented manually by experts, is developed to generate pixel-wise apparent flow between two time points of a 2D+t cine MRI image sequence. Combining the apparent flow maps and cardiac segmentation masks, we obtain a local apparent flow corresponding to the 2D motion of myocardium and ventricu…
Manual segmentation of the Left Ventricle (LV) is a tedious and meticulous task that can vary depending on the patient, the Magnetic Resonance Images (MRI) cuts and the experts. Still today, we consider manual delineation done by experts as being the ground truth for cardiac diagnosticians. Thus, we are reviewing the paper - written by Avendi and al. - who presents a combined approach with Convolutional Neural Networks, Stacked Auto-Encoders and Deformable Models, to try and automate the segmentation while performing more accurately. Furthermore, we have implemented parts of the paper (around …
CRUNet-MR-Univ: A Foundation Model for Diverse Cardiac MRI Reconstruction
Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands（莱顿大学医学中心放射科）；Philips Innovative Technologies, Hamburg, Germany（飞利浦创新技术）
Segmentation of the left ventricle (LV) from cardiac magnetic resonance imaging (MRI) datasets is an essential step for calculation of clinical indices such as ventricular volume and ejection fraction. In this work, we employ deep learning algorithms combined with deformable models to develop and evaluate a fully automatic segmentation tool for the LV from short-axis cardiac MRI datasets. The method employs deep learning algorithms to learn the segmentation task from the ground true data. Convolutional networks are employed to automatically detect the LV chamber in MRI dataset. Stacked autoenc…
Friedrich-Alexander-University Erlangen-Nuremberg（埃尔朗根-纽伦堡弗里德里希-亚历山大大学）；University of Leeds（利兹大学）
Quantitative assessment of cardiac left ventricle (LV) morphology is essential to assess cardiac function and improve the diagnosis of different cardiovascular diseases. In current clinical practice, LV quantification depends on the measurement of myocardial shape indices, which is usually achieved by manual contouring of the endo- and epicardial. However, this process subjected to inter and intra-observer variability, and it is a time-consuming and tedious task. In this paper, we propose a spatio-temporal multi-task learning approach to obtain a complete set of measurements quantifying cardia…
CONICET - FCEN, Universidad Nacional de Cuyo（阿根廷国家科学与技术研究理事会 - 库约国立大学自然科学学院）；Centro Integral de Medicina Nuclear y Radioterapia Bariloche（巴里洛切核医学与放射治疗综合中心）
Cardiac function is of paramount importance for both prognosis and treatment of different pathologies such as mitral regurgitation, ischemia, dyssynchrony and myocarditis. Cardiac behavior is determined by structural and functional features. In both cases, the analysis of medical imaging studies requires to detect and segment the myocardium. Nowadays, magnetic resonance imaging (MRI) is one of the most relevant and accurate non-invasive diagnostic tools for cardiac structure and function. In this work we propose to use a deep learning technique to assist the automatization of myocardial segmen…
School of Medicine, University College Dublin（都柏林大学学院医学院）；School of Computer Science, University College Dublin（都柏林大学学院计算机科学学院）；Department of Statistics, University of Wisconsin–Madison（威斯康星大学麦迪逊分校统计系）
Cardiac Magnetic Resonance (CMR) is the most effective tool for the assessment and diagnosis of a heart condition, which malfunction is the world's leading cause of death. Software tools leveraging Artificial Intelligence already enhance radiologists and cardiologists in heart condition assessment but their lack of transparency is a problem. This project investigates if it is possible to discover concepts representative for different cardiac conditions from the deep network trained to segment crdiac structures: Left Ventricle (LV), Right Ventricle (RV) and Myocardium (MYO), using explainabilit…
Heart Institute (InCor/HC.FMUSP)（心脏研究所（InCor/HC.FMUSP））
CNN (Convolutional Neural Network) models have been successfully used for segmentation of the left ventricle (LV) in cardiac MRI (Magnetic Resonance Imaging), providing clinical measurements. In practice, two questions arise with deployment of CNNs: 1) when is it better to use a shallow model instead of a deeper one? 2) how the size of a dataset might change the network performance? We propose a framework to answer them, by experimenting with deep and shallow versions of three U-Net families, trained from scratch in six subsets varying from 100 to 10,000 images, different network sizes, learni…
Robust Deep Learning for Myocardial Scar Segmentation in Cardiac MRI with Noisy Labels
Department of Cardiovascular Sciences, University of Leicester, Leicester, UK（莱斯特大学心血管科学系）；NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK（莱斯特生物医学研究中心）；Department of Information Engineering and Mathematics, University of Siena, Italy（锡耶纳大学信息工程与数学系）；Department of Mathematics, University of Leicester, Leicester, UK（莱斯特大学数学系）；Department of Computer Science, University of Copenhagen, Copenhagen, DK（哥本哈根大学计算机科学系）
Enhancing Implicit Neural Representations with Image Feature Embedding for Unsupervised Cardiac Cine MRI Reconstruction
Division of Image Processing, Department of Radiology, Leiden University Medical Center（莱顿大学医学中心放射科图像处理部）；C.J. Gorter Center, Department of Radiology, Leiden University Medical Center（莱顿大学医学中心放射科C.J. 戈特中心）；Cardio Vascular Imaging Group, Department of Radiology, Leiden University Medical Center（莱顿大学医学中心放射科心血管成像组）；Philips Innovative Technologies（飞利浦创新技术公司）
CMRINet: Joint Groupwise Registration and Segmentation for Cardiac Function Quantification from Cine-MRI
Leiden University Medical Center（莱顿大学医学中心）；University of Sheffield（谢菲尔德大学）；INSIGNEO；Institute for In Silico Medicine（计算医学研究所）；Department of Infection, Immunity and Cardiovascular Disease（感染、免疫与心血管疾病部门）；Sheffield Teaching Hospitals（谢菲尔德教学医院）；Department of Clinical Radiology（临床放射学部门）
Assessing the structure and function of the right ventricle (RV) is important in the diagnosis of several cardiac pathologies. However, it remains more challenging to segment the RV than the left ventricle (LV). In this paper, we focus on segmenting the RV in both short (SA) and long-axis (LA) cardiac MR images simultaneously. For this task, we propose a new multi-input/output architecture, hybrid 2D/3D geometric spatial TransformEr Multi-Pass fEature pyRAmid (Tempera). Our feature pyramid extends current designs by allowing not only a multi-scale feature output but multi-scale SA and LA input…
Contrast-Free Myocardial Scar Segmentation in Cine MRI using Motion and Texture Fusion
University of Oxford（牛津大学）；University of Southampton（南安普顿大学）；National University of Singapore（新加坡国立大学）；Fudan University（复旦大学）；Zhongshan Hospital, Fudan University（复旦大学附属中山医院）
Automated segmentation of human cardiac magnetic resonance datasets has been steadily improving during recent years. However, these methods are not directly applicable in preclinical context due to limited datasets and lower image resolution. Successful application of deep architectures for rat cardiac segmentation, although of critical importance for preclinical evaluation of cardiac function, has to our knowledge not yet been reported. We developed segmentation models that expand on the standard U-Net architecture and evaluated separate models for systole and diastole phases, 2MSA, and one m…
